The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport

Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome

(2016) Andrey G. Baranovskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Charge Transport within the Cell

(2015) Michael A. Grodick et al.   BIOCHEMISTRY

Emerging critical roles of Fe–S clusters in DNA replication and repair

(2015) Jill O. Fuss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Essential role of the iron-sulfur cluster binding domain of the primase regulatory subunit Pri2 in DNA replication initiation

(2015) Lili Liu et al.   Protein & Cell

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

(2015) Roxana E Georgescu et al.   eLife

Crystal Structure of the Human Primase

(2014) Andrey G. Baranovskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-Range Electron Tunneling

(2014) Jay R. Winkler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Mediated Signaling by Proteins with 4Fe–4S Clusters Is Necessary for Genomic Integrity

(2014) Michael A. Grodick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mammalian iron–sulphur proteins: novel insights into biogenesis and function

(2014) Tracey A. Rouault   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch

(2014) Neal F. Lue et al.   Nature Communications

Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase

(2013) Sivaraja Vaithiyalingam et al.   JOURNAL OF MOLECULAR BIOLOGY

Multiplexed Electrochemistry of DNA-Bound Metalloproteins

(2013) Catrina G. Pheeney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures of human primase reveal design of nucleotide elongation site and mode of Pol   tethering

(2013) M. L. Kilkenny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya

(2013) M. O'Donnell et al.   Cold Spring Harbor Perspectives in Biology

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

(2013) Rajika L Perera et al.   eLife

A Conserved Motif in the C-terminal Tail of DNA Polymerase α Tethers Primase to the Eukaryotic Replisome

(2012) Mairi L. Kilkenny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA charge transport as a first step in coordinating the detection of lesions by repair proteins

(2012) P. A. Sontz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the C-terminal domain of human DNA primase large subunit

(2011) Vinod B. Agarkar et al.   CELL CYCLE

ATP-Stimulated, DNA-Mediated Redox Signaling by XPD, a DNA Repair and Transcription Helicase

(2011) Timothy P. Mui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes

(2011) Daili J A Netz et al.   Nature Chemical Biology

DNA charge transport over 34 nm

(2011) Jason D. Slinker et al.   Nature Chemistry

Flexible tethering of primase and DNA Pol α in the eukaryotic primosome

(2011) Rafael Núñez-Ramírez et al.   NUCLEIC ACIDS RESEARCH

Electron flow through metalloproteins

(2010) Harry B. Gray et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Multiplexed DNA-Modified Electrodes

(2010) Jason D. Slinker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase

(2010) Ludovic Sauguet et al.   PLoS One

Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase

(2010) S. Vaithiyalingam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism and evolution of DNA primases

(2009) Robert D. Kuchta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases

(2009) Sebastian Klinge et al.   EMBO JOURNAL

Redox signaling between DNA repair proteins for efficient lesion detection

(2009) A. K. Boal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Valence photoionization and photofragmentation of aromatic amino acids

(2008) Oksana Plekan et al.   MOLECULAR PHYSICS

Tryptophan-Accelerated Electron Flow Through Proteins

(2008) C. Shih et al.   SCIENCE