Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body

Mechanisms and Consequences of Macromolecular Phase Separation

(2016) Louis-Philippe Bergeron-Sandoval et al.   CELL

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Nucleation by rRNA Dictates the Precision of Nucleolus Assembly

(2016) Hanieh Falahati et al.   CURRENT BIOLOGY

Cycling in the nucleus: regulation of RNA 3′ processing and nuclear organization of replication-dependent histone genes

(2016) Valentina Romeo et al.   CURRENT OPINION IN CELL BIOLOGY

Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos

(2016) Prachi N. Ghule et al.   DEVELOPMENTAL BIOLOGY

Droplet organelles?

(2016) Edward M Courchaine et al.   EMBO JOURNAL

Organ identity specification factor WGE localizes to the histone locus body and regulates histone expression to ensure genomic stability inDrosophila

(2016) Nao Ozawa et al.   GENES TO CELLS

Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis

(2016) Deirdre C. Tatomer et al.   JOURNAL OF CELL BIOLOGY

Nuclear bodies: Built to boost

(2016) Iain A. Sawyer et al.   JOURNAL OF CELL BIOLOGY

Mapping the Interaction Network of Key Proteins Involved in Histone mRNA Generation: A Hydrogen/Deuterium Exchange Study

(2016) Aleksandra Skrajna et al.   JOURNAL OF MOLECULAR BIOLOGY

A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues

(2016) Shawn M. Lyons et al.   NUCLEIC ACIDS RESEARCH

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency

(2015) Prachi N Ghule et al.   CELL CYCLE

Nuclear bodies: the emerging biophysics of nucleoplasmic phases

(2015) Lian Zhu et al.   CURRENT OPINION IN CELL BIOLOGY

Interrogating the Function of Metazoan Histones using Engineered Gene Clusters

(2015) Daniel J. McKay et al.   DEVELOPMENTAL CELL

The Y3** ncRNA promotes the 3′ end processing of histone mRNAs

(2015) Marcel Köhn et al.   GENES & DEVELOPMENT

Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription

(2015) Li Ling Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body

(2015) Esteban A. Terzo et al.   MOLECULAR BIOLOGY OF THE CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

(2015) Matthias Altmeyer et al.   Nature Communications

FLASH and NPAT positive but not Coilin positive Cajal bodies correlate with cell ploidy

(2014) Lucilla Bongiorno-Borbone et al.   CELL CYCLE

Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division

(2014) Alice Grob et al.   CELL CYCLE

Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division

(2014) A. Grob et al.   GENES & DEVELOPMENT

A Conserved Interaction That Is Essential for the Biogenesis of Histone Locus Bodies

(2014) Xiao-cui Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assemblages: Functional units formed by cellular phase separation

(2014) Jeffrey A. Toretsky et al.   JOURNAL OF CELL BIOLOGY

Fidelity of Histone Gene Regulation Is Obligatory for Genome Replication and Stability

(2014) P. N. Ghule et al.   MOLECULAR AND CELLULAR BIOLOGY

RNA binding by Hfq and ring-forming (L)Sm proteins

(2014) Oliver Weichenrieder   RNA Biology

Dynamic control of Cajal body number during zebrafish embryogenesis

(2014) Magdalena Strzelecka et al.   Nucleus

Drosophila Symplekin localizes dynamically to the histone locus body and tricellular junctions

(2014) Deirdre C Tatomer et al.   Nucleus

Protein disorder, prion propensities, and self-organizing macromolecular collectives

(2013) Liliana Malinovska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains

(2013) Ilmin Kwon et al.   CELL

A Sequence in the Drosophila H3-H4 Promoter Triggers Histone Locus Body Assembly and Biosynthesis of Replication-Coupled Histone mRNAs

(2013) Harmony R. Salzler et al.   DEVELOPMENTAL CELL

Gene-Specific Transcriptional Mechanisms at the Histone Gene Cluster Revealed by Single-Cell Imaging

(2013) Benjamin Guglielmi et al.   MOLECULAR CELL

3'-End processing of histone pre-mRNAs in Drosophila: U7 snRNP is associated with FLASH and polyadenylation factors

(2013) I. Sabath et al.   RNA

CSR-1 RNAi pathway positively regulates histone expression inC. elegans

(2012) Daphne C Avgousti et al.   EMBO JOURNAL

A Complex Containing the CPSF73 Endonuclease and Other Polyadenylation Factors Associates with U7 snRNP and Is Recruited to Histone Pre-mRNA for 3'-End Processing

(2012) X.-C. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetic Silencing of Core Histone Genes by HERS in Drosophila

(2012) Saya Ito et al.   MOLECULAR CELL

Ars2 Promotes Proper Replication-Dependent Histone mRNA 3′ End Formation

(2012) Joshua J. Gruber et al.   MOLECULAR CELL

Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes

(2012) Bo Cheng et al.   MOLECULAR CELL

H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes

(2012) Kiran Mahajan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA Polymerase II Pausing Downstream of Core Histone Genes Is Different from Genes Producing Polyadenylated Transcripts

(2012) Krishanpal Anamika et al.   PLoS One

Cajal bodies: where form meets function

(2012) Martin Machyna et al.   Wiley Interdisciplinary Reviews-RNA

Drosophilahistone locus bodies form by hierarchical recruitment of components

(2011) Anne E. White et al.   JOURNAL OF CELL BIOLOGY

Seed and grow: a two-step model for nuclear body biogenesis: Figure 1.

(2011) Miroslav Dundr   JOURNAL OF CELL BIOLOGY

Nucleation of nuclear bodies by RNA

(2011) Sergey P. Shevtsov et al.   NATURE CELL BIOLOGY

FLASH is essential during early embryogenesis and cooperates with p73 to regulate histone gene transcription

(2011) A De Cola et al.   ONCOGENE

Myc Localizes to Histone Locus Bodies during Replication in Drosophila

(2011) Kaveh Daneshvar et al.   PLoS One

Interaction between FLASH and Lsm11 is essential for histone pre-mRNA processing in vivo in Drosophila

(2011) B. D. Burch et al.   RNA

Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability

(2010) Jinfang Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DrosophilaOctamer Elements and Pdm-1 Dictate the Coordinated Transcription of Core Histone Genes

(2010) Mei-Chin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Muscle wasted: a novel component of the Drosophila histone locus body required for muscle integrity

(2010) S. Bulchand et al.   JOURNAL OF CELL SCIENCE

In vivo kinetics of U4/U6·U5 tri-snRNP formation in Cajal bodies

(2010) Ivan Novotný et al.   MOLECULAR BIOLOGY OF THE CELL

Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function

(2010) Marc-David Ruepp et al.   MOLECULAR BIOLOGY OF THE CELL

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

(2010) Yuntao S. Mao et al.   NATURE CELL BIOLOGY

Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis

(2010) Magdalena Strzelecka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biogenesis of Nuclear Bodies

(2010) M. Dundr et al.   Cold Spring Harbor Perspectives in Biology

Nuclear Bodies: Random Aggregates of Sticky Proteins or Crucibles of Macromolecular Assembly?

(2009) A. Gregory Matera et al.   DEVELOPMENTAL CELL

CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing

(2009) Judith Pirngruber et al.   EMBO REPORTS

Interaction of FLASH with Arsenite Resistance Protein 2 Is Involved in Cell Cycle Progression at S Phase

(2009) M. Kiriyama et al.   MOLECULAR AND CELLULAR BIOLOGY

Small Cajal Body–specific RNAs of Drosophila Function in the Absence of Cajal Bodies

(2009) Svetlana Deryusheva et al.   MOLECULAR BIOLOGY OF THE CELL

Coilin Is Essential for Cajal Body Organization in Drosophila melanogaster

(2009) Ji-Long Liu et al.   MOLECULAR BIOLOGY OF THE CELL

FLASH, a Proapoptotic Protein Involved in Activation of Caspase-8, Is Essential for 3′ End Processing of Histone Pre-mRNAs

(2009) Xiao-cui Yang et al.   MOLECULAR CELL

FLASH degradation in response to UV-C results in histone locus bodies disruption and cell-cycle arrest

(2009) L Bongiorno-Borbone et al.   ONCOGENE

The Drosophila U7 snRNP proteins Lsm10 and Lsm11 are required for histone pre-mRNA processing and play an essential role in development

(2009) A. C. Godfrey et al.   RNA

Poly (ADP-Ribose) Polymerase 1 Is Required for Protein Localization to Cajal Body

(2009) Elena Kotova et al.   PLoS Genetics

Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3′-end maturation

(2008) Nikolay G Kolev et al.   EMBO REPORTS

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

(2008) William F. Marzluff et al.   NATURE REVIEWS GENETICS

FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci

(2008) A H Alm-Kristiansen et al.   ONCOGENE

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

(2008) P. N. Ghule et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De Novo Formation of a Subnuclear Body

(2008) T. E. Kaiser et al.   SCIENCE