Journal
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Volume 109, Issue 6, Pages 473-476Publisher
ARAN EDICIONES, S A
DOI: 10.17235/reed.2017.4819/2016
Keywords
Recurrent Clostridium difficile infection; Ulcerative pancolitis; Fecal microbiota transplantation; Inflammatory bowel disease; Infectious colitis
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The use of fecal microbiota transplantation in recurrent Clostridium difficile infection and coexistent inflammatory bowel disease remains unclear. A 61-year-old man with ulcerative pancolitis was diagnosed with a third recurrence of Clostridium difficile infection, previously treated with metronidazole, vancomycin and fidaxomicin. Fecal microbiota transplantation of an unrelated healthy donor was performed by the lower route. After a twelve month follow-up, the patient remains asymptomatic without Clostridium difficile infection relapses or inflammatory bowel disease flare-ups. Fecal microbiota transplantation is relatively simple to perform, well-tolerated, safe and effective in recurrent Clostridium difficile infection with ulcerative pancolitis, as an alternative in case of antibiotic therapy failure.
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