Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Javier A. Crosby, Carolina Musri, Maria do Carmo Borges de Souza, A. Gustavo Martinez, Adelino Amaral Silva, Jose Maria Mojarra, Diego Masoli, Natalia Posada
Summary: This study examined the utilization, effectiveness, and safety of assisted reproductive technology (ART) in Latin America in 2019. The results showed an increase in ART utilization and a shift towards frozen-thawed embryo transfers. Selective single-embryo transfer (SET) was found to be important in reducing multiple births.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Vera Ruth Mitter, Pascale Fasel, Claudia Berlin, Sofia Amylidi-Mohr, Beatrice Mosimann, Marcel Zwahlen, Michael von Wolff, Alexandra Sabrina Kohl Schwartz
Summary: This study compared the perinatal outcomes of stimulated and unstimulated IVF babies with all children born in Switzerland, and found that stimulated IVF babies had higher risks of low birthweight and being small for gestational age, while unstimulated IVF babies had no significant increased risks compared to all Swiss children.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Audrey M. Marsidi, Lauren M. Kipling, Jennifer F. Kawwass, Akanksha Mehta
Summary: The study found that paternal age has an impact on the likelihood of pregnancy and live birth among couples undergoing assisted reproductive technology, especially in women aged 35 and older. Compared to paternal age under 45, paternal age over 46 is associated with lower success rates in IVF cycles.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Paversan Archary, Liezel Potgieter, Eman Elgindy, Rudolph Kantum Adageba, Justin Mboloko, Faye Iketubosin, Gamal Serour, Silke Dyer
Summary: This study investigates the utilization, practices, and outcomes of assisted reproductive technology (ART) in Africa in 2018 and 2019. The results show an increasing trend in the utilization of ART, with a high rate of multiple pregnancies, highlighting the need for improved follow-up of ART pregnancies.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Javier A. Crosby, Carolina Musri, Fanny Petermann-Rocha, Maria do Carmo Borges de Souza, A. Gustavo Martinez, Ricardo Azambuja, Armando Roque, Gustavo Estofan
Summary: This study investigated the utilization, effectiveness, and safety of assisted reproductive technology (ART) in Latin America in 2020. The results showed that Brazil, Mexico, and Argentina were the major contributors, with Uruguay having the highest utilization rate. The number of women aged 40 and above increased, while those aged 34 and below decreased. Single-embryo transfer became more common, but the rate of multiple births also increased. Frozen embryo transfer had a significantly higher delivery rate compared to fresh transfers. Preimplantation genetic testing improved delivery rate and decreased miscarriage rates.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Obstetrics & Gynecology
Willem Ombelet, Jonathan Van Blerkom, Geeta Nargund, Mia Janssen, Petra Jacobs, Ingrid Van der Auwera, Nathalie Dhont, Eugene Bosmans, Viktor-Jan Vertessen, Rudi Campo
Summary: This study compared the perinatal outcomes of babies conceived through different assisted reproductive technologies and found no significant difference in the perinatal outcomes of babies conceived through a simplified IVF culture system and intracytoplasmic sperm injection.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Review
Medicine, General & Internal
Lauren Lacey, Sibte Hassan, Sebastian Franik, Mourad W. Seif, M. Ahsan Akhtar
Summary: The effects of assisted hatching (AH) on live birth rates are uncertain and may increase the risk of multiple pregnancies. Although AH may offer a slightly increased chance of achieving a clinical pregnancy, the quality of data is low, and it is uncertain whether it influences miscarriage rates.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Multidisciplinary Sciences
Rosemond Akpene Hiadzi, Isaac Mensah Boafo, Peace Mamle Tetteh
Summary: This study explores the impact of religion on ART usage, suggesting that religion is not an inhibiting factor but rather an enabling factor for participants. It provides a framework for participants to navigate decision-making, treatment processes, and outcomes, and offers strength to endure the physical and emotional discomfort associated with ART.
Article
Obstetrics & Gynecology
Georgina M. Chambers, Silke Dyer, Fernando Zegers-Hochschild, Jacques de Mouzon, Osamu Ishihara, Manish Banker, Ragaa Mansour, Markus S. Kupka, G. David Adamson
Summary: In 2014, 1.93 million ART cycles were performed in 76 countries, with trends showing increased success rates, frozen embryo transfer cycles, single embryo transfer, and preimplantation genetic testing. Utilization rates and effectiveness of ART continue to improve globally.
HUMAN REPRODUCTION
(2021)
Article
Medicine, General & Internal
Willem Ombelet, Jonathan Van Blerkom, Liesbeth Bruckers, Nathalie Dhont, Geeta Nargund, Rudi Campo
Summary: To make IVF more affordable, researchers have developed a simplified culture system (SCS) that has proven to be effective. Compared to conventional IVF, singletons born after using SCS have significantly lower rates of preterm birth and low birthweight. These findings offer a promising perspective for implementing low-cost IVF in low and middle income countries (LMIC).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Siri E. Haberg, Christian M. Page, Yunsung Lee, Haakon E. Nustad, Maria C. Magnus, Kristine L. Haftorn, Ellen O. Carlsen, William R. P. Denault, Jon Bohlin, Astanand Jugessur, Per Magnus, Hakon K. Gjessing, Robert Lyle
Summary: Assisted reproductive technology (ART) may affect fetal development through epigenetic mechanisms, leading to widespread differences in DNA methylation and variations in genes related to growth, neurodevelopment, and other health outcomes.
NATURE COMMUNICATIONS
(2022)
Article
Obstetrics & Gynecology
Tanja Premru-Srsen, Eda Bokal Vrtacnik, Tina Bizjak, Ivan Verdenik, Sara Korosec, Helena Ban Frangez
Summary: The study suggests that preterm delivery is a modest adverse outcome in infertile women who conceive after reproductive surgery, compared to fertile women. The risk of preterm delivery after natural conception or IVF/ICSI treatment following reproductive surgery is not significantly higher among infertile women when compared to fertile women.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Manish Banker, Silke Dyer, Georgina M. Chambers, Osamu Ishihara, Markus Kupka, Jacques de Mouzon, Fernando Zegers-Hochschild, G. David Adamson
Summary: The report provides data on the utilization, effectiveness, and safety of assisted reproductive technology (ART) globally in 2013, showing an increase in ART cycles and changes in trends such as a rise in the proportion of older women undergoing non-donor ART. Further efforts are needed to improve the quality and consistency of reporting ART data by registries.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Caitlin R. Sacha, Daksha Gopal, Chia-Ling Liu, Howard R. Cabral, Judy E. Stern, Daniela A. Carusi, Catherine Racowsky, Charles L. Bormann
Summary: This study compares the obstetric and perinatal outcomes of single-step and sequential culture media systems for embryo conception. The results indicate that single-step culture is associated with increased odds of LGA, while there were no significant differences in other outcomes.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Claudia Massarotti, Sara Stigliani, Arianna Ramone, Francesca Bovis, Fausta Sozzi, Valentino Remorgida, Angelo Cagnacci, Paola Anserini, Paola Scaruffi
Summary: Suboptimal prolonged ovarian stimulation can induce the occurrence of smooth endoplasmic reticulum aggregates (SERa) in oocytes, thereby reducing their reproductive potential. The transfer of embryos from cycles with SERa+ oocytes showed lower clinical success, emphasizing the importance of proper timing and stimulation protocols to maximize oocyte quality and quantity.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier A. Crosby, Carolina Musri, Maria do Carmo Borges de Souza
REPRODUCTIVE BIOMEDICINE ONLINE
(2015)
Article
Obstetrics & Gynecology
Juan-Enrique Schwarze, Javier A. Crosby, Fernando Zegers-Hochschild
REPRODUCTIVE BIOMEDICINE ONLINE
(2015)
Article
Obstetrics & Gynecology
Juan-Enrique Schwarze, Javier A. Crosby, Fernando Zegers-Hochschild
FERTILITY AND STERILITY
(2016)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier Crosby, Carolina Musri, Maria Teresa Urbina
REPRODUCTIVE BIOMEDICINE ONLINE
(2018)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier A. Crosby, Carolina Musri, Maria Teresa Urbina
REPRODUCTIVE BIOMEDICINE ONLINE
(2019)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Javier A. Crosby, Carolina Musri, Maria do Carmo Borges de Souza, A. Gustavo Martinez, Adelino Amaral Silva, Jose Maria Mojarra, Diego Masoli, Natalia Posada
REPRODUCTIVE BIOMEDICINE ONLINE
(2020)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Javier A. Crosby, Carolina Musri, Maria do Carmo Borges de Souza, A. Gustavo Martinez, Adelino Amaral Silva, Jose Maria Mojarra, Diego Masoli, Natalia Posada
Summary: This study examined the utilization, effectiveness, and safety of assisted reproductive technology (ART) in Latin America in 2019. The results showed an increase in ART utilization and a shift towards frozen-thawed embryo transfers. Selective single-embryo transfer (SET) was found to be important in reducing multiple births.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Javier A. Crosby, Carolina Musri, Maria do Carmo Borges de Souza, A. Gustavo Martinez, Adelino Amaral Silva, Jose Maria Mojarra, Diego Masoli, Natalia Posada
Summary: The retrospective collection of multinational data on assisted reproductive technology (ART) in Latin America over the past three decades shows trends in patient characteristics, effectiveness, and safety. The Latin American Registry of Assisted Reproduction (RLA) has played a key role in facilitating technological transfer and regional growth in the field.
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2021)
Article
Obstetrics & Gynecology
Antonio MacKenna, Javier Crosby, Cristian Huidobro, Eduardo Correa, Gonzalo Duque
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2017)
Article
Obstetrics & Gynecology
Juan Enrique Schwarze, Javier Crosby
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2017)
Article
Obstetrics & Gynecology
Juan-Enrique Schwarze, Rodrigo Jeria, Javier Crosby, Sonia Villa, Carolina Ortega, Ricardo Pommer
HUMAN REPRODUCTION OPEN
(2017)
Article
Obstetrics & Gynecology
Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier A. Crosby, Carolina Musri, Maria Teresa Urbina
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2016)
Article
Obstetrics & Gynecology
Alice Newman-Sanders, Jackson C. Kirkman-Brown, Meurig T. Gallagher
Summary: This study revealed a significant lack of awareness among young adults in the UK regarding the potential impacts of gym lifestyles and supplementation on male infertility. Men were found to have a concerning lack of concern for their own fertility, with differences in awareness levels between men and women. It was also observed that men were more likely to consider making changes to their behavior if it had a long-term impact on their fertility compared to short-term effects.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Shachar Reuvenny, Michal Youngster, Almog Luz, Rohi Hourvitz, Ettie Maman, Micha Baum, Ariel Hourvitz
Summary: Using a machine-learning model to determine the optimal trigger days can improve the outcomes of antagonist protocol cycles in freeze-all or fresh transfer cycles, for all age groups. Implementing these models can more accurately predict the number of retrieved oocytes, optimizing physicians' decisions, balancing workloads, and creating more standardized yet patient-specific protocols.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Chao Chen, Qi Wen, Feng Deng, Rong Li, Ying Wang, Xiumei Zhen, Jing Hang
Summary: This study investigates the proteomic and phosphoproteomic differences in the endometrium of women with recurrent pregnancy loss (RPL) compared to healthy control women during different phases of the menstrual cycle. The results identify differentially expressed proteins and phosphorylated proteins, and highlight the insulin/cyclic nucleotide signalling pathway and AMPK/mTOR signalling pathway as major contributors to the abnormality of RPL endometrium. The findings provide insights into potential proteins associated with the pathogenesis of RPL and contribute to the identification of potential targets for RPL treatment.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)
Article
Obstetrics & Gynecology
Jaime Guerrero, Juan Carlos Castillo, Jorge Ten, Jose Antonio Ortiz, Belen Lledo, Domingo Orozco, Francisco Quereda, Andrea Bernabeu, Rafael Bernabeu
Summary: The study found no significant differences in clinical outcomes between using oocytes obtained from random-start protocols and those from conventional ovarian stimulation in oocyte donation treatments. Luteal-phase stimulation required longer stimulation and higher FSH consumption.
REPRODUCTIVE BIOMEDICINE ONLINE
(2024)