4.6 Article

Assisted reproduction techniques in Latin America: the Latin American Registry, 2014

Journal

REPRODUCTIVE BIOMEDICINE ONLINE
Volume 35, Issue 3, Pages 287-295

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.rbmo.2017.05.021

Keywords

Assisted reproductive technology; Epidemiology; IVF-ICSI; Latin America; Perinatal outcome; Registry

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Multinational data on assisted reproduction techniques [IVF and intractytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, pre-implantation genetic diagnosis and fertility preservation) were collected from 159 institutions in 15 Latin American countries. A total of 41.34% of IVF-CSI cycles were conducted in women aged 35-39 years and 23.35% in women aged 40 years and older. After removing freeze-all cases, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20.78% twins and 0.92% triplets and over. In oocyte donation, twins reached 28.93% and triplets 1.07%. Preterm deliveries reached 16.4% in singletons, 55.02% in twins and 76% in triplets. Perinatal mortality in 18,162 births was 23 per 1000 in singletons, 35 per 1000 in twins, and 36 per 1000 in high-order multiples. Elective single embryo transfer represented 2.63% of fresh transfers, with a 32.15% delivery rate per transfer. Elective double embryo transfer represented 23.74% of transfers, with a 41.03% delivery rate per transfer; 11,373 babies [62.6%] were singletons; 6398 [5.2%] twins, and 391 [.2%], triplets and more. Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred is mandatory. (C) 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

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