Calcium oxalate crystals induces tight junction disruption in distal renal tubular epithelial cells by activating ROS/Akt/p38 MAPK signaling pathway

Podophyllotoxin acetate enhances γ-ionizing radiation-induced apoptotic cell death by stimulating the ROS/p38/caspase pathway

(2015) Jae Yeon Choi et al.   BIOMEDICINE & PHARMACOTHERAPY

Apoptotic events induced by high glucose in human hepatoma HepG2 cells involve endoplasmic reticulum stress and MAPK’s activation

(2014) Qiaoling Jiang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxidative Stress Mediates the Disruption of Airway Epithelial Tight Junctions through a TRPM2-PLCγ1-PKCα Signaling Pathway

(2013) Rui Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Giardia duodenalisAssemblage-Specific Induction of Apoptosis and Tight Junction Disruption in Human Intestinal Epithelial Cells: Effects of Mixed Infections

(2013) Wan Hon Koh et al.   JOURNAL OF PARASITOLOGY

p38 MAPK mediates calcium oxalate crystal-induced tight junction disruption in distal renal tubular epithelial cells

(2013) Paleerath Peerapen et al.   Scientific Reports

Gallotannin Suppresses Calcium Oxalate Crystal Binding and Oxalate-Induced Oxidative Stress in Renal Epithelial Cells

(2012) Hyo-Jung Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Changes in Mitochondrial Proteome of Renal Tubular Cells Induced by Calcium Oxalate Monohydrate Crystal Adhesion and Internalization Are Related to Mitochondrial Dysfunction

(2012) Sakdithep Chaiyarit et al.   JOURNAL OF PROTEOME RESEARCH

Reactive Oxygen Species as the Molecular Modulators of Calcium Oxalate Kidney Stone Formation: Evidence from Clinical and Experimental Investigations

(2012) Saeed R. Khan   JOURNAL OF UROLOGY

ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation

(2011) Xin Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Species-Activated Akt/ASK1/p38 Signaling Pathway in Nickel Compound-Induced Apoptosis in BEAS 2B Cells

(2010) Jingju Pan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

First Prize (Tie): Oxidative Renal Cell Injury Induced by Calcium Oxalate Crystal and Renoprotection with Antioxidants: A Possible Role of Oxidative Stress in Nephrolithiasis

(2010) Mauricio Davalos et al.   JOURNAL OF ENDOUROLOGY

Effects of calcium oxalate monohydrate crystals on expression and function of tight junction of renal tubular epithelial cells

(2010) Paleerath Peerapen et al.   LABORATORY INVESTIGATION

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Calcium Kidney Stones

(2010) Elaine M. Worcester et al.   NEW ENGLAND JOURNAL OF MEDICINE

Switching Akt: from survival signaling to deadly response

(2009) Marek Los et al.   BIOESSAYS

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Oxidative stress-induced disruption of epithelial and endothelial tight junctions

(2008) Radhakrishna Rao   Frontiers in Bioscience-Landmark

Survival Signaling by C-RAF: Mitochondrial Reactive Oxygen Species and Ca2+ Are Critical Targets

(2008) A. V. Kuznetsov et al.   MOLECULAR AND CELLULAR BIOLOGY

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

(2007) Kohsuke Takeda et al.   Annual Review of Pharmacology and Toxicology