Advances in on-chip vascularization

Fabrication of biomimetic vascular scaffolds for 3D tissue constructs using vascular corrosion casts

(2016) Jennifer Huling et al.   Acta Biomaterialia

In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels

(2016) Nathalie Brandenberg et al.   ADVANCED MATERIALS

Three-dimensional biomimetic model to reconstitute sprouting lymphangiogenesis in vitro

(2016) Sudong Kim et al.   BIOMATERIALS

3D-printed fluidic networks as vasculature for engineered tissue

(2016) Ian S. Kinstlinger et al.   LAB ON A CHIP

Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels

(2016) Xiaolin Wang et al.   LAB ON A CHIP

Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis

(2016) Boyang Zhang et al.   NATURE MATERIALS

Morphogenesis of 3D vascular networks is regulated by tensile forces

(2016) Dekel Rosenfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

(2016) Anna Herland et al.   PLoS One

Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting

(2016) Yue Du et al.   Scientific Reports

3D microtumors in vitro supported by perfused vascular networks

(2016) Agua Sobrino et al.   Scientific Reports

Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

(2015) Skarphedinn Halldorsson et al.   BIOSENSORS & BIOELECTRONICS

Investigation of Tumor Cell Behaviors on a Vascular Microenvironment-Mimicking Microfluidic Chip

(2015) Rong Huang et al.   Scientific Reports

In Vitro Recapitulation of Functional Microvessels for the Study of Endothelial Shear Response, Nitric Oxide and [Ca2+]i

(2015) Xiang Li et al.   PLoS One

3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs

(2014) David B. Kolesky et al.   ADVANCED MATERIALS

Microvascular Endothelial Cells Migrate Upstream and Align Against the Shear Stress Field Created by Impinging Flow

(2014) Maggie A. Ostrowski et al.   BIOPHYSICAL JOURNAL

The complexity of cell composition of the intima of large arteries: focus on pericyte-like cells

(2014) A. N. Orekhov et al.   CARDIOVASCULAR RESEARCH

Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems

(2014) Jessie S. Jeon et al.   Integrative Biology

MicroRNA-21 regulates the sensitivity to cisplatin in a human osteosarcoma cell line

(2014) W. Ziyan et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Engineering interconnected 3D vascular networks in hydrogels using molded sodium alginate lattice as the sacrificial template

(2014) Xue-Ying Wang et al.   LAB ON A CHIP

Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs

(2014) Luiz E. Bertassoni et al.   LAB ON A CHIP

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Imaging pericytes and capillary diameter in brain slices and isolated retinae

(2014) Anusha Mishra et al.   Nature Protocols

Human Vascular Tissue Models Formed from Human Induced Pluripotent Stem Cell Derived Endothelial Cells

(2014) David G. Belair et al.   Stem Cell Reviews and Reports

A novel tissue model for angiogenesis: evaluation of inhibitors or promoters in tissue level

(2014) Bingling Dai et al.   Scientific Reports

Hypertensive stretch regulates endothelial exocytosis of Weibel-Palade bodies through VEGF receptor 2 signaling pathways

(2013) Yan Xiong et al.   CELL RESEARCH

Mechanisms of tumor cell extravasation in an in vitro microvascular network platform

(2013) Michelle B. Chen et al.   Integrative Biology

Complementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting

(2013) Sei Hien Lim et al.   Integrative Biology

A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays

(2013) Yu-Hsiang Hsu et al.   LAB ON A CHIP

A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture

(2013) Ilka Wagner et al.   LAB ON A CHIP

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Formation of microvascular networks in vitro

(2013) John P Morgan et al.   Nature Protocols

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

(2013) S. Munster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro

(2013) D.-H. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vitro Perfused Human Capillary Networks

(2013) Monica L. Moya et al.   TISSUE ENGINEERING PART C-METHODS

Control of Perfusable Microvascular Network Morphology Using a Multiculture Microfluidic System

(2013) Jordan A. Whisler et al.   TISSUE ENGINEERING PART C-METHODS

In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels

(2013) Hidekazu Sekine et al.   Nature Communications

Hydrogels for biomedical applications

(2012) Allan S. Hoffman   ADVANCED DRUG DELIVERY REVIEWS

Multilayered Blood Capillary Analogs in Biodegradable Hydrogels for In Vitro Drug Permeability Assays

(2012) Hiroaki Yoshida et al.   ADVANCED FUNCTIONAL MATERIALS

Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels

(2012) Lauren L. Bischel et al.   BIOMATERIALS

Mechanism of a flow-gated angiogenesis switch: early signaling events at cell–matrix and cell–cell junctions

(2012) Vernella Vickerman et al.   Integrative Biology

Mechanical Behavior of Collagen-Fibrin Co-Gels Reflects Transition From Series to Parallel Interactions With Increasing Collagen Content

(2012) Spencer P. Lake   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

In vitro formation and characterization of a perfusable three-dimensional tubular capillary network in microfluidic devices

(2012) Ju Hun Yeon et al.   LAB ON A CHIP

Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)

(2012) Ross Booth et al.   LAB ON A CHIP

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Ensemble Analysis of Angiogenic Growth in Three-Dimensional Microfluidic Cell Cultures

(2012) Waleed A. Farahat et al.   PLoS One

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis, properties and biomedical applications of poly(glycerol sebacate) (PGS): A review

(2012) Ranjana Rai et al.   PROGRESS IN POLYMER SCIENCE

Vascularization is the key challenge in tissue engineering

(2011) Esther C. Novosel et al.   ADVANCED DRUG DELIVERY REVIEWS

SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures

(2011) Nasser Sadr et al.   BIOMATERIALS

A novel in vitro angiogenesis model based on a microfluidic device

(2011) XiaoZhen Dai et al.   CHINESE SCIENCE BULLETIN

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

(2011) Andrew C. Newman et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular control of endothelial cell behaviour during blood vessel morphogenesis

(2011) Shane P. Herbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fluid forces control endothelial sprouting

(2011) J. W. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels

(2010) Gavrielle M. Price et al.   BIOMATERIALS

Vascular permeability modulation at the cell, microvessel, or whole organ level: towards closing gaps in our knowledge

(2010) F.-R. E. Curry et al.   CARDIOVASCULAR RESEARCH

Endothelial [Ca2+]i and caveolin-1 antagonistically regulate eNOS activity and microvessel permeability in rat venules

(2010) Xueping Zhou et al.   CARDIOVASCULAR RESEARCH

Shear stress and the endothelial transport barrier

(2010) John M. Tarbell   CARDIOVASCULAR RESEARCH

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Transmural pressure and axial loading interactively regulate arterial remodeling ex vivo

(2009) Amanda R. Lawrence et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review

(2009) G. Kovacs et al.   EUROPEAN RESPIRATORY JOURNAL

Judah Folkman, a pioneer in the study of angiogenesis

(2008) Domenico Ribatti   ANGIOGENESIS

Endothelial Cell Layer Subjected to Impinging Flow Mimicking the Apex of an Arterial Bifurcation

(2008) Michael P. Szymanski et al.   ANNALS OF BIOMEDICAL ENGINEERING

Endothelial cell polarization and chemotaxis in a microfluidic device

(2008) Amir Shamloo et al.   LAB ON A CHIP

Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging

(2008) Vernella Vickerman et al.   LAB ON A CHIP

Cell migration into scaffolds under co-culture conditions in a microfluidic platform

(2008) Seok Chung et al.   LAB ON A CHIP

Effect of cyclic AMP on barrier function of human lymphatic microvascular tubes

(2008) Gavrielle M. Price et al.   MICROVASCULAR RESEARCH

Non-invasive measurement of solute permeability in cerebral microvessels of the rat

(2008) Wei Yuan et al.   MICROVASCULAR RESEARCH