Article
Chemistry, Physical
Yifei Yang, Rui Sun, Yossef A. Elabd
Summary: In this study, a new template-assisted electrospinning/electrospraying (E/E) technique was developed to fabricate organized-structured nanofiber/nanoparticle electrodes with well-defined 3D hexagonal patterned arrays of various sizes. The 80 mm diameter hexagonal patterned electrodes showed higher fuel cell power densities and electrochemical surface areas compared to random electrodes, with improved mechanical stiffness and platinum utilization. The E/E technique provides a versatile platform for investigating the effect of pattern type and size on fuel cell platinum utilization under ultra-low platinum loadings.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Nanoscience & Nanotechnology
Jun Liu, Siyu Wu, Jiayi Ma, Chun Liu, Ting Dai, Xiaoyu Wu, Hongbin Zhao, Dong Zhou
Summary: This study manufactured nanofibrous scaffolds incorporating different ratios of attapulgite (ATP) and Hydroxyapatite (HA) to enhance the osteoinductive effect in bone tissue engineering. The synergistic effect of ATP and HA on bone formation was explored both in vivo and in vitro. The study found that the ATP/HA ratio of 2:1 had the most significant synergistic effect.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Polymer Science
Giada Loi, Franca Scocozza, Flaminia Aliberti, Lorenza Rinvenuto, Gianluca Cidonio, Nicola Marchesi, Laura Benedetti, Gabriele Ceccarelli, Michele Conti
Summary: Cells are influenced by various biomechanical aspects of their microenvironment, such as substrate geometry. The effect of substrate geometry on muscle cell behavior, particularly in terms of cell proliferation, is known. However, its influence on the myogenic differentiation process is not clear and requires further investigation.
Article
Engineering, Biomedical
Xingliang Dai, Xuefeng Tian, Shengcai Gu, Yafei Yang, Huaixu Li, Peng Gao, Qing Lan, Hongwei Cheng
Summary: This study successfully fabricated neurosecretory structures with 3D bioprinting and nanofiber electrospinning in vitro. The hybrid biofabricated scaffold structure exhibited high mechanical strength and low cytotoxicity. The 3D-bioprinted tissue showed cell proliferation and secretion of neurotransmitters. In vivo transplantation experiments demonstrated the compatibility and remodeling ability of the tissue structures. These findings provide a new method for manufacturing neurosecretory structures in vitro and offer potential clinical applications.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Engineering, Biomedical
Adam A. Mieloch, Julia A. Semba, Jakub D. Rybka
Summary: This study investigated the potential of carbon nanotubes (CNT)-reinforced polycaprolactone (PCL) for three-dimensional (3D) bioprinting and tissue engineering. The addition of CNT improved the rheological and mechanical properties of the PCL material and enhanced cell adhesion and proliferation. This research provides a promising solution to overcome current limitations in 3D bioprinting by tailoring biomaterials for specific applications.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2022)
Article
Nanoscience & Nanotechnology
Xuanwen Xu, Yi Zhou, Kai Zheng, Xinyu Li, Lu Li, Yan Xu
Summary: Periodontitis is a chronic inflammatory disease that affects people worldwide and has an uncertain prognosis with surgical treatment. In this study, a three-dimensional scaffold made of electrospun polycaprolactone/gelatin fibrous membranes was developed to overcome the challenges of periodontal treatment. The scaffold showed good properties and promoted adhesion and proliferation of human periodontal ligament stem cells. In vivo experiments confirmed that the scaffold could guide cellular orientation and potentially facilitate periodontal regeneration.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biotechnology & Applied Microbiology
Liang Sun, Jianfeng Zhou, Yaoning Chen, Deng-Guang Yu, Ping Liu
Summary: Bacterial prostatitis is a challenging condition to treat, and this study aimed to develop a new hybrid material for more effective therapy. By combining electrosprayed core-shell microparticles and electrospun nanofibers, traditional Chinese medicine and Western medicine were encapsulated separately and released in a controlled manner. The hybrids showed superior antibacterial effects and have potential for convenient and synergistic treatment of bacterial prostatitis.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Polymer Science
Donghun Kim, Yoonjin Kim, Dokun Kim, Dongwan Son, Song Jun Doh, Myungwoong Kim, Hoik Lee, Ki Ro Yoon
Summary: The application of nanofiber and porous metal-organic framework for public health protection has gained increasing attention. A composite platform with lightweight and multifunctionality has been developed, providing physical sieving and gas capturing capabilities. By optimizing the fabrication process, a hybrid membrane comprised of nanofibers and MOF particles has been produced. The order of processing steps was varied to study its effect on air pollutant filtration, and the most desirable configuration for personal protection equipment was found to balance air permeability, filtration efficiency, and performance.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Engineering, Biomedical
Faraz Fazal, Francisco Javier Diaz Sanchez, Muhammad Waqas, Vasileios Koutsos, Anthony Callanan, Norbert Radacsi
Summary: A hybrid bioprinting-electrospinning system was developed to meet the high demand for small diameter vascular grafts with mechanical and biological properties similar to living tissues. The setup successfully addressed the limitations of current tissue-engineered vascular grafts, producing a layered structure capable of printing tubular constructs with cell-laden hydrogel and electrospun fibres.
MEDICAL ENGINEERING & PHYSICS
(2021)
Article
Materials Science, Composites
Elham Sadeghi, Seyed Mojtaba Zebarjad, Farzaneh Khademi, Elham Bagherzadeh
Summary: In this study, PCL/Ge/HA core-shell nanocomposites were produced using coaxial electrospinning method. The resulting nanofibrous scaffolds showed good mechanical properties and biological activity, making them promising candidates for bone scaffolds.
POLYMER COMPOSITES
(2022)
Article
Engineering, Chemical
Tai Zhang, Changfa Xiao, Jian Zhao, Xiaozhen Liu, Dawei Ji, Hongyan Xu
Summary: The study presents a novel tubular nanofibers and micro/nanospheres covered composite membrane with superoleophilicity and superhydrophobicity, which demonstrates efficient separation performance for water-in-oil emulsions and robust recyclability. The method is simple, cost-effective, and has potential applications in practical oily wastewater purification.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Review
Pharmacology & Pharmacy
Zhen Wang, Yichuan Wang, Jiaqi Yan, Keshi Zhang, Feng Lin, Lei Xiang, Lianfu Deng, Zhenpeng Guan, Wenguo Cui, Hongbo Zhang
Summary: Bone regenerative engineering encompasses scaffold design and applications based on electrospinning and 3D bioprinting technologies, aiming to achieve bone tissue regeneration. Electrospun nanofibrous scaffolds and 3D bioprinted scaffolds play crucial roles in bone regeneration, with promising prospects for future development.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Article
Polymer Science
Zohre Mousavi Nejad, Ali Zamanian, Maryam Saeidifar, Hamid Reza Vanaei, Mehdi Salar Amoli
Summary: The PCL/BG and PCL/HyA scaffolds fabricated by 3D printing technology showed great potential for promoting dentin and pulp tissue regeneration, with the former exhibiting higher bioactivity and surface roughness, and the latter enhancing cell adhesion and hydrophilicity. Gene expression results demonstrated increased expression of odontogenic markers with both scaffolds, indicating their suitability for hDPSC adhesion and odontogenic differentiation.
Article
Biochemistry & Molecular Biology
Seyed Mahdi Sadraei, Jafar Kiani, Behnaz Ashtari
Summary: A novel nanocomposite scaffold material was studied, which enhanced the regenerative processes of nerve cells by incorporating gold nanorods. The experimental results showed that the nanocomposite material had good electrical conductivity and wettabilty, and promoted cell maturation and neurogenic differentiation, indicating its great potential for regeneration.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Textiles
Emre Yavuz, Ramazan Erdem, Ertan Kucuksayan, Esin Akarsu, Murat Akarsu
Summary: Hydroxyapatite particles were modified with polyethylene glycol functional silane successfully, maintaining crystal structure unchanged. Electrospun nanofibrous biomembranes incorporating modified HAP exhibited higher cellular protein expression compared to unmodified biomembranes.
FIBERS AND POLYMERS
(2021)
Article
Mathematics, Interdisciplinary Applications
Shuhao Wang, Lida Zhu, Yichao Dun, Zhichao Yang, Jerry Ying Hsi Fuh, Wentao Yan
Summary: A high-fidelity model was developed to simulate the detailed multi-layer deposition process, which found that build-ups are mainly induced by unstable linear powder feed rate and worsen due to laser/powder defocusing and accumulated heat. Eliminating methods were proposed and validated by experiments.
COMPUTATIONAL MECHANICS
(2021)
Article
Chemistry, Physical
Qiqiang Cao, Zhuoqi Shi, Yuchao Bai, Jiong Zhang, Cuiling Zhao, Jerry Ying Hsi Fuh, Hao Wang
Summary: This paper presents a novel method to improve the machinability of cone support structures by filling epoxy resin in the gaps between support structures. The method not only corrects the problems of support tilting and collapsing but also significantly reduces cutting force, tool wear, and damage to the workpiece surface.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Otorhinolaryngology
Joshua K. Tay, Gail B. Cross, Song Tar Toh, Chun Kiat Lee, Jerold Loh, Zhen Yu Lim, Nicholas Ngiam, Jeremy Chee, Soo Wah Gan, Anmol Saraf, Wai Tung Eason Chow, Han Lee Goh, Chor Hiang Siow, Derrick W. Q. Lian, Woei Shyang Loh, Kwok Seng Loh, Chwee Ming Lim, Ying Ying Chua, Thuan Tong Tan, Hiang Khoon Tan, Benedict Yan, Karrie Ko, Kian Sing Chan, Lynette Oon, Vincent T. K. Chow, De Yun Wang, Jerry Y. H. Fuh, Ching-Chiuan Yen, John E. L. Wong, David M. Allen
Summary: The study aimed to determine the accuracy and acceptability of three-dimensionally printed nasopharyngeal swabs (3DP swabs) in identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Results showed that the 3DP swab performed accurately and consistently across health care institutions in patients with COVID-19.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Engineering, Manufacturing
Wenjun Ge, Jerry Y. H. Fuh, Suck Joo Na
Summary: A 3D numerical model was developed to simulate the keyhole mode in selective laser melting process, providing detailed simulations of molten pool flow and temperature field. The study results can guide the optimization of manufacturing process parameters.
JOURNAL OF MANUFACTURING PROCESSES
(2021)
Article
Chemistry, Physical
Xianyin Duan, Xinyue Chen, Kunpeng Zhu, Tao Long, Shiyang Huang, Fuh Y. H. Jerry
Summary: In the selective laser melting process, temperature and stress distribution evolution have a significant impact on the microstructure, build quality, and mechanical properties of components. Finite element methods are used to simulate and predict the building process to monitor temperature and stress distribution changes in real time. Experimental results suggest that optimizing laser power, scanning speed, and spot diameter parameters can improve the build quality of SLM parts.
Article
Engineering, Manufacturing
Guo Yilin, Jerry Fuh Ying Hsi, Lu Wen Feng
Summary: Additive manufacturing allows for complex geometries in parts, expanding the design space to microarchitecture scale. Optimizing structures within this expanded design space can improve performance. A surrogate model based on 3D convolutional neural networks provides flexibility in predicting material properties of microscale structures.
VIRTUAL AND PHYSICAL PROTOTYPING
(2021)
Article
Nanoscience & Nanotechnology
Xue Wang, Liping Zhao, Jerry Ying Hsi Fuh, Heow Pueh Lee
Summary: This paper analyzes the effects of statistical pore characteristics on the mechanical behavior of LPBF processed parts and proposes a micromechanical model to predict the mechanical properties of the materials. The relationship among pore features is studied to gain insights on how the pore details affect the tensile behavior of the parts.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Engineering, Multidisciplinary
Chenyang Zhao, Yueping Xi, Yizhi Shao, Wen Xue, Daxiang Deng, Yang Wu
Summary: This paper investigates a novel template-matching-based precision measurement method that integrates polar microstructure and computer vision (IPMCV). Three crucial factors that affect the measurement performance of the IPMCV method are determined. The experimental results are significant for parameter determination and optimization to achieve better measurement performance.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2022)
Article
Automation & Control Systems
Kunpeng Zhu, Jerry Ying Hsi Fuh, Xin Lin
Summary: Metal-based additive manufacturing (MAM) processes show great potential in various industrial applications, but defects in the process can greatly impact the quality and reliability of the final products. MAM process monitoring, especially with the use of machine learning (ML) frameworks, is crucial for improving build quality and eliminating defects. This article discusses different monitoring methods and proposes a ML framework for process condition monitoring, highlighting the importance of advancing ML-based research in this field.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2022)
Article
Robotics
Diancheng Li, Dongliang Fan, Renjie Zhu, Qiaozhi Lei, Yuxuan Liao, Xin Yang, Yang Pan, Zheng Wang, Yang Wu, Sicong Liu, Hongqiang Wang
Summary: In this study, origami-inspired soft pneumatic actuators (OSPAs) made from silicone are introduced. The OSPAs can provide multiple rotations and have a significantly higher rotation ratio compared to other similar products. The study team also demonstrates the potential applications of OSPAs in grippers, robot arms, and snake robots.
Review
Engineering, Biomedical
Yang Wu, Ming Li, Hao Su, Huaying Chen, Yonggang Zhu
Summary: This review discusses the major considerations, challenges, and potential strategies for bone bioprinting, and summarizes the latest progress in this field. It uncovers the immense potential of bioprinting in re-establishing the 3D dynamic microenvironment of the native bone, and can assist researchers in reconstructing clinically relevant bone tissues with appropriate mechanical properties and precisely regulated biological behaviors.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Review
Engineering, Biomedical
Yang Wu, Hao Su, Ming Li, Huayang Xing
Summary: This paper focuses on the development of DLP-based multi-material 3D printing technology and its applications in the field of bioprinting, providing an outlook on future efforts to overcome the challenges and obstacles of this promising technique.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Editorial Material
Engineering, Manufacturing
Hao Wang, Jerry Ying Hsi Fuh
JOURNAL OF MANUFACTURING AND MATERIALS PROCESSING
(2023)
Review
Engineering, Biomedical
Harish K. Handral, Vaishali P. Natu, Tong Cao, Jerry Y. H. Fuh, Gopu Sriram, Wen F. Lu
BIO-DESIGN AND MANUFACTURING
(2022)
Article
Automation & Control Systems
Kunpeng Zhu, Jerry Ying Hsi Fuh, Xin Lin
Summary: Defects in metal-based additive manufacturing processes hinder its reliable application in critical industries like aerospace and medical, highlighting the importance of process monitoring. A machine learning framework provides a technical basis for monitoring, with shallow and deep learning methods proposed in this article for monitoring the MAM process.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2022)
