Article
Multidisciplinary Sciences
Mikiyas Amare Getu, Panpan Wang, Eva Johanna Kantelhardt, Edom Seife, Changying Chen, Adamu Addissie
Summary: This study aimed to examine the validity and reliability of the EORTC QLQ-BR45 questionnaire among breast cancer patients in Ethiopia. The results showed that the questionnaire has good reliability and validity, and can be used to assess the quality of life of breast cancer patients.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Meena N. Murugappan, Bellinda L. King-Kallimanis, Christina Mangir, Lynn Howie, Vishal Bhatnagar, Julia A. Beaver, Ethan M. Basch, Sydney R. Henson, Paul G. Kluetz
Summary: This study analyzed the floor/ceiling effects in the physical functioning domain of patients with advanced/metastatic breast cancer in commercial clinical trials and a community-based trial. The results showed minor floor effects and notable ceiling effects at both the item and scale levels, regardless of the cohort. This may pose challenges in detecting changes in physical functioning among high-functioning patients.
Article
Oncology
Axel Budde, Katja Baust, Leonie Weinhold, Mark Bernstein, Stefan Bielack, Catharina Dhooge, Lars Hjorth, Katherine A. Janeway, Meriel Jenney, Mark D. Krailo, Neyssa Marina, Rajaram Nagarajan, Sigbjorn Smeland, Matthew R. Sydes, Patricia De Vos, Jeremy Whelan, Andreas Wiener, Gabriele Calaminus, Matthias Schmid
Summary: This study assessed the feasibility of harmonizing data from pediatric and adult quality-of-life assessments and found that score linking provides clinicians and researchers with a common metric for assessing patients' quality of life.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Medicine, General & Internal
Rachel S. van Leeuwaarde, Angelica M. Gonzalez-Clavijo, Marc Pracht, Galina Emelianova, Winson Y. Cheung, Christina Thirlwell, Kjell Oberg, Francesca Spada
Summary: This study aims to assess patients' perceptions of the EORTC QLQ-C30 and EORTC QLQ-G.I.NET21 questionnaires in neuroendocrine neoplasms (NENs). The study found that there are limitations in the design of the questions and the patients' satisfaction reporting of the questionnaire.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Nern Hoong Kao, N. Gopalakrishna Iyer, Alice Chua, Rahul Harshad Nagadia
Summary: This study evaluated the quality of life of head and neck cancer survivors after surgical treatment, specifically focusing on eating-related concerns. Factors such as advanced tumor stage, extent of surgery, and adjuvant treatment were found to be associated with lower overall health scores. Improvement in quality of life was observed in previous studies after one year.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Laura A. Gray, Monica Hernandez Alava, Allan J. Wailoo
Summary: This study investigates the relationship between EQ-5D-3L and QLQ-C30 in breast cancer patients, providing a mapping model for cost-effectiveness analysis. Using a mixture model, QLQ-C30 scores were successfully converted to EQ-5D-3L scores, offering reliable estimates for economic evaluation of breast cancer health technologies.
Article
Cardiac & Cardiovascular Systems
Markus S. Anker, Sophia K. Potthoff, Alessia Lena, Jan Porthun, Sara Hadzibegovic, Ruben Evertz, Corinna Denecke, Ann-Kathrin Froehlich, Frederike Sonntag, Vera Regitz-Zagrosek, Stuart D. Rosen, Alexander R. Lyon, Thomas F. Luescher, John A. Spertus, Stefan D. Anker, Mahir Karakas, Lars Bullinger, Ulrich Keller, Ulf Landmesser, Javed Butler, Stephan von Haehling
Summary: This study compared the EORTC QLQ-C30 and ESC HeartQoL questionnaires for assessing health-related quality of life in cancer patients, and found that both instruments were associated with increased mortality in cancer patients. Combining both questionnaires provided even greater stratification of patient risk.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Oncology
Quirien Oort, Hanneke Zwinkels, Johan A. F. Koekkoek, Maaike J. Vos, Jaap C. Reijneveld, Martin J. B. Taphoorn, Linda Dirven
Summary: This study evaluated the effectiveness of using the EORTC QLQ-C30 Emotional Functioning scale as a screening measure for mood disorders in glioma patients. The results showed a strong correlation with the Hospital Anxiety and Depression Scale and demonstrated good discriminating capabilities, making it a suitable tool for identifying patients at risk of mood disorders.
Article
Oncology
O. Sjokvist, S. Hakansson, E. Pantiora, A. Karakatsanis
Summary: The study revealed that the HRQoL reference values for the outpatient breast clinic population were lower, with more severe symptoms and lower functionality compared to the general population. This suggests that the reference values may not accurately reflect the quality of life of the study population.
Article
Oncology
Carlos H. Barrios, Shigehira Saji, Nadia Harbeck, Hong Zhang, Kyung H. Jung, Sheetal Patel, Shilpen Patel, Anh Nguyen Duc, Mario Liste-Hermoso, Stephen Y. Chui, Elizabeth A. Mittendorf
Summary: This study assessed patients' experience of treatment burden when adding atezolizumab to neoadjuvant chemotherapy for early-stage TNBC. The results showed that adding atezolizumab did not impose additional treatment burden on patients while improving pathologic complete response.
Article
Oncology
Mikiyas Amare Getu, Changying Chen, Panpan Wang, Eva Johanna Kantelhardt, Adamu Addissie
Summary: This study aimed to assess the quality of life and its influencing factors among breast cancer patients using a specific questionnaire. The results showed that future perspective had the lowest score, and financial difficulties, appetite loss, and fatigue were the most common symptoms. There were correlations between tumor stage and certain symptoms, and patients without comorbidities had better function in some areas.
Article
Oncology
Maria Rothmund, Micha J. J. Pilz, Nathalie Egeter, Emma Lidington, Claire Piccinin, Juan I. I. Arraras, Mogens Gronvold, Bernhard Holzner, Marieke van Leeuwen, Morten Aa. Petersen, Heike Schmidt, Teresa Young, Johannes M. M. Giesinger, EORTC Quality Life Grp
Summary: This study compared the content of commonly used patient-reported outcome measures (PROMs) and found that they cover 132 unique items primarily focusing on emotional functioning, with the majority of items falling under the third-level category of "emotional functions, other specified".
Article
Health Care Sciences & Services
Takuya Kawahara, Naruto Taira, Takeru Shiroiwa, Yasuhiro Hagiwara, Takashi Fukuda, Yukari Uemura, Hirofumi Mukai
Summary: This study aimed to establish minimal important differences (MIDs) for the EORTC QLQ-C30 in patients with metastatic breast cancer. Using data from a randomized clinical trial, we estimated MIDs for 8 scales of the QLQ-C30. Patient-reported anchors were found to be more sensitive to early changes in health status.
QUALITY OF LIFE RESEARCH
(2022)
Article
Oncology
Michele Reni, Julia Braverman, Andrew Hendifar, Chung-Pin Li, Teresa Macarulla, Do-Youn Oh, Hanno Riess, Margaret Tempero, Brian Lu, James Marcus, Namita Joshi, Marc Botteman, Amylou C. Dueck
Summary: The study calculated the minimal important difference (MID) and responder definition (RD) of EORTC QLQ-PAN26 questionnaire in patients with pancreatic cancer who received adjuvant chemotherapy in the APACT trial. Results showed that anchor-based MIDs were twice as sensitive as distribution-based MIDs in detecting group-level changes in QLQ-PAN26 scales/items.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
James W. F. Catto, Pramit Khetrapal, Federico Ricciardi, Gareth Ambler, Norman R. Williams, Tarek Al-Hammouri, Muhammad Shamim Khan, Ramesh Thurairaja, Rajesh Nair, Andrew Feber, Simon Dixon, Senthil Nathan, Tim Briggs, Ashwin Sridhar, Imran Ahmad, Jaimin Bhatt, Philip Charlesworth, Christopher Blick, Marcus G. Cumberbatch, Syed A. Hussain, Sanjeev Kotwal, Anthony Koupparis, John McGrath, Aidan P. Noon, Edward Rowe, Nikhil Vasdev, Vishwanath Hanchanale, Daryl Hagan, Chris Brew-Graves, John D. Kelly
Summary: This study compared the recovery and morbidity of patients undergoing robot-assisted radical cystectomy with intracorporeal reconstruction versus open radical cystectomy for bladder cancer. The results showed that robot-assisted surgery resulted in a statistically significant increase in the number of days alive and out of the hospital within 90 days of surgery. In addition, robot-assisted surgery had lower rates of thromboembolic and wound complications compared to open surgery. Patients who underwent robot-assisted surgery also reported better quality of life and less disability compared to those who underwent open surgery.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)