Saikosaponin D relieves unpredictable chronic mild stress induced depressive-like behavior in rats: involvement of HPA axis and hippocampal neurogenesis

BE360, a new selective estrogen receptor modulator, produces antidepressant and antidementia effects through the enhancement of hippocampal cell proliferation in olfactory bulbectomized mice

(2016) Osamu Nakagawasai et al.   BEHAVIOURAL BRAIN RESEARCH

Apigenin ameliorates chronic mild stress-induced depressive behavior by inhibiting interleukin-1β production and NLRP3 inflammasome activation in the rat brain

(2016) Ruipeng Li et al.   BEHAVIOURAL BRAIN RESEARCH

Electroconvulsive stimulation results in long-term survival of newly generated hippocampal neurons in rats

(2016) Mikkel Vestergaard Olesen et al.   HIPPOCAMPUS

Chinese herbal medicines promote hippocampal neuroproliferation, reduce stress hormone levels, inhibit apoptosis, and improve behavior in chronically stressed mice

(2016) Gao-Ge Sun et al.   JOURNAL OF ETHNOPHARMACOLOGY

Glucocorticoids Suppress the Protective Effect of Cyclooxygenase-2-Related Signaling on Hippocampal Neurogenesis Under Acute Immune Stress

(2016) Yanbo Ma et al.   MOLECULAR NEUROBIOLOGY

Glucocorticoid receptor translocation and expression of relevant genes in the hippocampus of adolescent and adult male rats

(2016) Matthew R. Green et al.   PSYCHONEUROENDOCRINOLOGY

A Chinese herbal decoction, reformulated from Kai-Xin-San, relieves the depression-like symptoms in stressed rats and induces neurogenesis in cultured neurons

(2016) Lu Yan et al.   Scientific Reports

Baicalin promotes hippocampal neurogenesis via SGK1- and FKBP5-mediated glucocorticoid receptor phosphorylation in a neuroendocrine mouse model of anxiety/depression

(2016) Kuo Zhang et al.   Scientific Reports

Thymol produces an antidepressant-like effect in a chronic unpredictable mild stress model of depression in mice

(2015) Xue-Yang Deng et al.   BEHAVIOURAL BRAIN RESEARCH

Fluoxetine Regulates Neurogenesis In Vitro Through Modulation of GSK-3 / -Catenin Signaling

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Saikosaponin-D Attenuates Heat Stress-Induced Oxidative Damage in LLC-PK1 Cells by Increasing the Expression of Anti-Oxidant Enzymes and HSP72

(2014) Bao-Zhen Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Emodin opposes chronic unpredictable mild stress induced depressive-like behavior in mice by upregulating the levels of hippocampal glucocorticoid receptor and brain-derived neurotrophic factor

(2014) Meng Li et al.   FITOTERAPIA

The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition

(2014) Mónica Morais et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Fluoxetine treatment ameliorates depression induced by perinatal arsenic exposure via a neurogenic mechanism

(2014) Christina R. Tyler et al.   NEUROTOXICOLOGY

Saikosaponin D acts against corticosterone-induced apoptosis via regulation of mitochondrial GR translocation and a GR-dependent pathway

(2014) Zong-Yang Li et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

(2013) Ian Mahar et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis

(2013) C. Anacker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010

(2013) Alize J. Ferrari et al.   PLOS MEDICINE

A Functional Role for CREB as a Positive Regulator of Memory Formation and LTP

(2013) Satoshi Kida   Experimental Neurobiology

Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction

(2012) Marni N. Silverman et al.   Annals of the New York Academy of Sciences

Emerging drugs for major depressive disorder

(2012) Kevin Ryan Connolly et al.   EXPERT OPINION ON EMERGING DRUGS

Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder

(2012) Adriana Medina et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Glucocorticoid Receptor and FKBP5 Expression Is Altered Following Exposure to Chronic Stress: Modulation by Antidepressant Treatment

(2012) Gianluigi Guidotti et al.   NEUROPSYCHOPHARMACOLOGY

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

(2012) Shuichi Chiba et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling

(2011) J C Garza et al.   MOLECULAR PSYCHIATRY

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

(2011) C Anacker et al.   MOLECULAR PSYCHIATRY

Antidepressants recruit new neurons to improve stress response regulation

(2011) A Surget et al.   MOLECULAR PSYCHIATRY

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress

(2010) Girstautė Dagytė et al.   BEHAVIOURAL BRAIN RESEARCH

Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory

(2009) V K Parihar et al.   MOLECULAR PSYCHIATRY

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Age-dependent effects of chronic stress on brain plasticity and depressive behavior

(2008) Erika Toth et al.   JOURNAL OF NEUROCHEMISTRY

Glucocorticoid Receptor Phosphorylation Differentially Affects Target Gene Expression

(2008) Weiwei Chen et al.   MOLECULAR ENDOCRINOLOGY

The total flavonoids extracted from Xiaobuxin-Tang up-regulate the decreased hippocampal neurogenesis and neurotrophic molecules expression in chronically stressed rats

(2008) Lei An et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY