Article
Clinical Neurology
Lauren M. Osborne, Kristin Voegtline, Lindsay R. Standeven, Bridget Sundel, Meeta Pangtey, Liisa Hantsoo, Jennifer L. Payne
Summary: Anxiety in pregnancy is a strong predictor of postpartum depression, with high worry being more indicative than psychiatric diagnosis or elevated antenatal depressive symptoms. The Penn State Worry Questionnaire (PSWQ) may be a valuable tool in identifying high worry during pregnancy.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Chenxinzi Lin, Bin Chen, Youjing Yang, Qianmin Li, Qiuguo Wang, Minmin Wang, Shiying Guo, Shasha Tao
Summary: This study conducted a meta-analysis to estimate the association between postpartum depression (PPD) and the COVID-19 pandemic. The results showed a significantly higher prevalence and odds of PPD in those who suffered from the pandemic. The study also found that China had a lower prevalence of postpartum depression compared to other countries during the COVID-19 pandemic.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Obstetrics & Gynecology
Alzina Koric, Bhavneet Singh, James A. VanDerslice, Joseph B. Stanford, Charles R. Rogers, Doreen T. Egan, Daniel O. Agyemang, Karen Schliep
Summary: Polycystic ovary syndrome is associated with postpartum depressed mood and symptoms among high-risk mothers, with prenatal depression and anxiety mediating this association. Nearly 20% of women in the population-based sample who reported at least 2 PCOS symptoms did not receive a clinical diagnosis, highlighting the importance of psychological screening among women with PCOS.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Clinical Neurology
Noa Gueron-Sela, Golan Shahar, Ella Volkovich, Liat Tikotzky
Summary: This study examined the role of sleep during pregnancy in predicting postpartum emotional distress trajectories. Results showed that mothers with shorter sleep durations during pregnancy were more likely to experience higher comorbidity or moderate symptoms, while mothers with poor sleep quality were more likely to fall into the moderate symptoms category.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Erica L. Eliason, Sarah H. Gordon
Summary: This study aims to explore the impact of California's Provisional Postpartum Care Extension (PPCE) on postpartum women. The findings suggest that PPCE could have extended postpartum coverage eligibility for approximately 30,360 women, but the narrow definition of eligibility criteria excluded many postpartum women in Medi-Cal.
WOMENS HEALTH ISSUES
(2022)
Article
Obstetrics & Gynecology
Mary Gemmel O'Donnell, Lauren Stumpp, Marcia J. Gallaher, Robert W. Powers
Summary: Approximately 20% of women experience stress-related mood disorders, such as depression and anxiety, during and after pregnancy, making them one of the most common complications of pregnancy. These disorders are associated with negative pregnancy outcomes, including gestational hypertension and preeclampsia, and can impact maternal vascular health postpartum. However, the direct effects and underlying mechanisms of stress on maternal vascular health remain understudied. This study aimed to investigate the impact of pre-pregnancy stress on maternal vascular outcomes using a mouse model of chronic unpredictable stress. The findings showed that pre-pregnancy stress increased blood pressure during pregnancy and impaired vascular function at the end of pregnancy, with these effects persisting into the postpartum period. These results suggest that exposure to stress and related disorders, even before pregnancy, can contribute to vascular complications during and after pregnancy.
REPRODUCTIVE SCIENCES
(2023)
Article
Clinical Neurology
Jennifer N. Felder, Elissa S. Epel, John Neuhaus, Andrew D. Krystal, Aric A. Prather
Summary: The study examines the effects of digital cognitive behavior therapy for insomnia (dCBT-I) during pregnancy on subjective sleep outcomes, depressive symptoms, and anxiety symptoms. The findings suggest that dCBT-I can improve postpartum insomnia remission rates and reduce the incidence of insomnia. Additionally, dCBT-I shows significant improvements in depressive and anxiety symptom severity, particularly among patients with minimal depressive symptoms at baseline.
Article
Psychology, Clinical
Beatriz Pereira, Barbara Figueiredo, Tiago Miguel Pinto, M. Carmen Miguez
Summary: This study demonstrated that previous tobacco consumption and anxiety symptoms are associated with higher smoking quantity during pregnancy, while depression symptoms are linked to smoking relapse during the postpartum period.
ADDICTIVE BEHAVIORS
(2022)
Article
Psychology, Multidisciplinary
Ines M. Tavares, Joana Fernandes, Catarina V. Moura, Pedro J. Nobre, Mariana L. Carrito
Summary: The study investigated the individual and relational well-being of women and men expecting their first child during the COVID-19 pandemic, with men under lockdown reporting higher levels of perceived stress and women reporting higher levels of depression and greater social support. Themes identified from qualitative analysis included Individual Changes and Relational Changes, indicating both personal concerns and relational issues affected by the pandemic.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Clinical Neurology
Berihun Assefa Dachew, Getinet Ayano, Kim Betts, Rosa Alati
Summary: The study found that pre-pregnancy obesity is associated with an increased risk of maternal depressive symptoms during both pregnancy and the postpartum period, while underweight, overweight, and obesity are also linked to postnatal depressive symptoms. However, the association between pre-pregnancy BMI and perinatal anxiety symptoms remains uncertain. Women with high or low pre-pregnancy weight may benefit from mental health screening and interventions during prenatal care.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Obstetrics & Gynecology
Shelby Howard, Caitlin Witt, Karla Martin, Ateshi Bhatt, Emily Venable, Sarah Buzhardt, Andrew G. Chapple, Elizabeth F. Sutton
Summary: This study aimed to investigate the incidence of depression, anxiety, and perinatal PTSD, as well as their co-occurrences, in a low-resource OB/GYN clinic. The results showed that these mental health conditions are independent risk factors for each other.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Obstetrics & Gynecology
Shahnaz Barat, Azita Ghanbarpour, Seyyedeh Mahboubeh Mirtabar, Farzan Kheirkhah, Zahra Basirat, Hoda Shirafkan, Angela Hamidia, Faezeh Khorshidian, Davood Hosseini Talari, Zeynab Pahlavan, Sedigheh Esmaelzadeh, Zinatosadat Buzari, Mahtab Zeynalzadeh, Shahla Yazdani Charati, Fatemeh Shafizade, Mahsima Adnani, Fatemeh Amirkhanloo, Maedeh Mollaalipour, Atieh Chale Kani, Mania Amiri, Razieh Khazaei, Seyedeh Shabnam Mehdinia, Fatemeh Basirat, Simin Asadollahi, Asieh Khodami, Alireza Azizi, Fatemeh Nasiri-Amiri, Nooshin Fatery, Shirin Shahrokhi, Banafshe Zarinkamar, Sajedeh Aligoltabar, Mahbobeh Faramarzi
Summary: This study aims to determine the prevalence and risk factors of psychological distress during pregnancy and postpartum in an Iranian population. The results showed that the prevalence of psychological distress was 19% during pregnancy and 15% during postpartum. High-risk pregnancy, gestational age less than 20 weeks, and residing in urban areas were identified as the main risk factors for psychological distress.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Psychiatry
Michele L. Okun, Andrew Lac
Summary: Insomnia and poor sleep quality during the perinatal period are common and are associated with increased risk of postpartum depression and anxiety. Evaluating and addressing sleep disturbances during the perinatal period may help reduce the risk of postpartum mood disorders and improve overall health outcomes.
PSYCHOSOMATIC MEDICINE
(2023)
Article
Nursing
Emily P. Rabinowitz, Lindsay A. Kutash, Alexis L. Richeson, MacKenzie A. Sayer, Marielle R. Samii, Douglas L. Delahanty
Summary: Symptoms of depression, anxiety, and stress in pregnant women generally decrease throughout pregnancy, reaching their lowest point in the postpartum period. The extent to which chronic stress during the COVID-19 pandemic alters these symptom trajectories in pregnant/postpartum women is unknown.
Article
Clinical Neurology
Briana N. C. Chronister, Eduardo Gonzalez, Dolores Lopez-Paredes, Jose Suarez-Torres, Sheila Gahagan, Danilo Martinez, Janeth Barros, David R. Jacobs, Harvey Checkoway, Jose R. Suarez-Lopez
Summary: This study found that elevated levels of testosterone, cortisol, and estradiol in adolescents were associated with altered mood. Cortisol and testosterone were significant effect modifiers in the relationships between most hormones and depression and anxiety.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Pediatrics
Mary C. Kimmel, Rheanna E. Platt, Danielle N. Steinberg, Fallon Cluxton-Keller, Lauren M. Osborne, Tracy Carter, Jennifer L. Payne, Barry S. Solomon
CLINICAL PEDIATRICS
(2017)
Article
Psychiatry
Kate Walsh, Archana Basu, Elizabeth Werner, Seonjoo Lee, Tianshu Feng, Lauren M. Osborne, Ashley Rainford, Michelle Gilchrist, Catherine Monk
PSYCHOSOMATIC MEDICINE
(2016)
Review
Psychiatry
Katherine McEvoy, Lauren M. Osborne, Julie Nanavati, Jennifer L. Payne
CURRENT PSYCHIATRY REPORTS
(2017)
Article
Obstetrics & Gynecology
Lauren M. Osborne
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA
(2018)
Review
Psychiatry
Katherine McEvoy, Jennifer L. Payne, Lauren M. Osborne
CURRENT PSYCHIATRY REPORTS
(2018)
Review
Immunology
Lauren M. Osborne, Amitoj Brar, Sabra L. Klein
BRAIN BEHAVIOR AND IMMUNITY
(2019)
Article
Endocrinology & Metabolism
Lauren M. Osborne, Gayane Yenokyan, Kezhen Fei, Thomas Kraus, Thomas Moran, Catherine Monk, Rhoda Sperling
PSYCHONEUROENDOCRINOLOGY
(2019)
Article
Psychiatry
Nomi S. Weiss-Laxer, Sara B. Johnson, Sharon R. Ghazarian, Lauren M. Osborne, Anne W. Riley
ARCHIVES OF WOMENS MENTAL HEALTH
(2020)
Article
Psychology, Multidisciplinary
Lauren M. Osborne, Joshua F. Betz, Gayane Yenokyan, Lindsay R. Standeven, Jennifer L. Payne
FRONTIERS IN PSYCHOLOGY
(2019)
Review
Psychiatry
Katherine McEvoy, Lauren M. Osborne
INTERNATIONAL REVIEW OF PSYCHIATRY
(2019)
Article
Education & Educational Research
Lee A. Robinson, Lauren M. Osborne, Alan J. Hsu, Henry Park, Melissa R. Arbuckle
ACADEMIC PSYCHIATRY
(2019)
Article
Health Policy & Services
Ruth C. Angrand, Rhoda Sperling, Kinga Roccobono, Lauren M. Osborne, Jennifer Jao
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
(2018)
Article
Education & Educational Research
Sarah Nagle-Yang, Laura Miller, Lauren M. Osborne
ACADEMIC PSYCHIATRY
(2018)
Article
Education & Educational Research
Lauren M. Osborne, Joanna V. MacLean, Erin Murphy Barzilay, Samantha Meltzer-Brody, Laura Miller, Sarah Nagle Yang
ACADEMIC PSYCHIATRY
(2018)
Article
Endocrinology & Metabolism
Shanshan Xiao, Natalie C. Ebner, Amirhossein Manzouri, Tie-Qiang Li, Diana S. Cortes, Kristoffer N. T. Mansson, Hakan Fischer
Summary: The mechanisms through which intranasal oxytocin affects the brain are not fully understood, but recent research suggests that brain regions with a higher density of oxytocin receptors may play a key role. This study used resting-state fMRI to investigate the effects of intranasal oxytocin administration on connectivity between these receptor-enriched regions and other regions in the brain, and found that the effects varied depending on the age of the participants.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Lisa Haase, Antonia Vehlen, Julia Strojny, Gregor Domes
Summary: This study found no significant changes in the cortisol awakening response (CAR) over the menstrual cycle, and no significant association with variations in estradiol and progesterone. These results suggest that CAR is largely robust against hormonal variations across the menstrual cycle.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Derek Schaeuble, Tyler Wallace, Sebastian A. Pace, Shane T. Hentges, Brent Myers
Summary: Depression and cardiovascular disease are influenced by daily life stress, but the biological mechanisms behind this connection are not well understood. This study shows that the ventromedial prefrontal cortex (vmPFC) plays a role in regulating stress responses and behavior, with sex-specific effects. In males, the vmPFC-PH circuitry promotes positive motivation and reduces stress responses, while in females it elevates stress responses. This suggests that cortical regulation of stress reactivity and behavior is mediated by projections to the hypothalamus in a sex-specific manner.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Jose M. Guzman, Montana H. Boone, Gabriela L. Suarez, Colter Mitchell, Christopher S. Monk, Luke W. Hyde, Nestor L. Lopez-Duran
Summary: The COVID-19 pandemic has led to increased life stress and internalizing disorders, with a disproportionate impact on women. This study focused on the neuroendocrinology of stress-related disorders and found that women have lower cortisol responses and higher DHEA responses to stress. However, lower cortisol and higher DHEA are associated with internalizing disorders in women, while the opposite is true in men. The study also examined the relationship between COVID-related stress and internalizing symptoms and found gender differences in the association between DHEA and cortisol and internalizing outcomes. These findings suggest distinct neuroendocrine pathways for stress-related disorders in young men and women.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Meriah L. Dejoseph, Keira B. Leneman, Alyssa R. Palmer, Emily R. Padrutt, Otiti A. Mayo, Daniel Berry
Summary: Childhood and adolescence are critical periods for the development of the stress response system. This study found a modest positive relation between the adrenocortical and sympathetic systems, as well as between the adrenocortical and parasympathetic systems. The strength of these associations varied based on methodological and sociodemographic characteristics.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Qiong Xiang, Jia-Sheng Tao, Shuai Dong, Xiao-Lin Liu, Liang Yang, Li-Ni Liu, Jing Deng, Xian-Hui Li
Summary: Chronic hyperglycemia accelerates the pathological process of cognitive dysfunction, but the heterogeneity of hippocampal cells under long-term high glucose conditions is not well known. In this study, single-cell RNA sequencing was performed on diabetic mice, and distinct cell sub-clusters and important genes involved in neuroplasticity regulation were identified.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Roger Mcintosh, Hannah Hoogerwoerd, Salman S. Ahmad, Cassandra Michel, Kaitlyn Dillon, Mahendra Kumar, Gail Ironson
Summary: The study found that a 4-session guided written emotional disclosure intervention led to significant reductions in total output and concentration of epinephrine in urine for up to 6 months in individuals living with HIV. This effect was especially pronounced in women. However, there were no significant changes in norepinephrine output in urine.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Meredith Gruhn, Adam Bryant Miller, Tory A. Eisenlohr-Moul, Sophia Martin, Matthew G. Clayton, Matteo Giletta, Paul D. Hastings, Matthew K. Nock, Karen D. Rudolph, George M. Slavich, Mitchell J. Prinstein, Margaret A. Sheridan
Summary: This study investigates how early life adversity characterized by threat impacts the association between neural activity and cortisol production during emotion processing. The results suggest that threat exposure may moderate the relationship between neural activation and cortisol response.
PSYCHONEUROENDOCRINOLOGY
(2024)
