Article
Oncology
Clare Meernik, Stephanie M. Engel, Christopher D. Baggett, Ally Wardell, Xi Zhou, Kathryn J. Ruddy, Ethan Wantman, Valerie L. Baker, Barbara Luke, Jennifer E. Mersereau, Jianwen Cai, Andrew F. Olshan, Andrew B. Smitherman, Hazel B. Nichols
Summary: Fertility preservation may be underused after cancer diagnosis due to concerns about delaying cancer treatment. However, this study found that fertility preservation can delay gonadotoxic cancer treatment without significantly impacting prognosis for most women.
Review
Oncology
Anao Zhang, Bradley Zebrack, Chiu Yi Tan, Emily Walling, Rashmi Chugh
Summary: This study conducted a systematic review and meta-analysis of psychosocial, behavioral, and supportive interventions for pediatric, adolescent, and young adult cancer survivors, showing an overall moderate and statistically significant treatment effect size. However, interventions were not effective for certain outcome domains, and less effective among adolescent and young adult compared to pediatric cancer survivors.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Article
Oncology
Elizabeth J. Siembida, Bryce B. Reeve, Brad J. Zebrack, Mallory A. Snyder, John M. Salsman
Summary: The study examined the variability in HRQOL among adolescent and young adult cancer survivors, finding that treatment status and developmental stage significantly impacted symptoms and functioning, with developmental stage being a more critical predictor than cancer type.
Article
Oncology
Viswatej Avutu, Kathleen A. Lynch, Marie E. Barnett, Jacqueline A. Vera, Julia Glade L. Bender, William D. Tap, Thomas M. Atkinson
Summary: Adolescents and young adults (AYAs) have unique needs and face worse outcomes in cancer care compared to children and older adults. Understanding their psychosocial and informational needs is crucial for improving cancer care delivery. This study interviewed AYAs with cancer to understand their perspectives, identify needs, and develop recommendations for cancer care delivery and accommodations.
Review
Oncology
Natalie K. Bradford, Fiona E. J. McDonald, Helen Bibby, Cindy Kok, Pandora Patterson
Summary: This systematic review examines the long-term outcomes of cancer treatment in adolescents and young adults. The results indicate that psychological and functional health outcomes improve over time, although there are inconsistencies in reported health behaviors. Neurocognitive deficits affect the ability to work, and the impacts on fertility and sexuality are sustained. However, the long-term impact of cancer on other important domains remains largely unknown.
Review
Oncology
Niki Oveisi, Vicki Cheng, Ursula Ellis, Stuart Peacock, Helen McTaggart-Cowan, Lori A. Brotto, Jonathan Loree, Gillian E. Hanley, Sharlene Gill, Meera Rayar, Amirrtha Srikanthan, Mary A. De Vera
Summary: This systematic review and meta-analysis examined the impacts of cancer on reproductive health outcomes in adolescents and young adults (AYAs) aged 15-39 years. The analysis included 21 studies and assessed 62 reproductive outcomes. The results showed that AYA cancer patients have a higher risk of preterm birth, gestational diabetes, and use of fertility treatment compared to controls, especially among those who received radiation.
Review
Oncology
Silvie H. M. Janssen, Winette T. A. van der Graaf, Daniel J. van der Meer, Eveliene Manten-Horst, Olga Husson
Summary: Adolescent and young adult (AYA) cancer patients, aged 15-39 years old, face unique challenges in their disease trajectory. Although the number of AYA cancer survivors has increased, they are at risk of long-term and late effects. Research efforts are needed to inform survivorship care for this growing population.
Article
Oncology
Ursula M. Sansom-Daly, Claire E. Wakefield, Christina Signorelli, Mark W. Donoghoe, Antoinette Anazodo, Susan M. Sawyer, Michael Osborn, Rosalie Viney, Nicholas Daniell, Kate Faasse, Richard J. Cohn
Summary: Adolescent and young adult cancer survivors face significant physical/mental health late effects following cancer treatment, which can be minimized through tailored healthcare use. A cross-sectional study found that cancer survivors reported greater use of medical and mental health services, particularly females, those diagnosed with brain/solid tumors, and those more recently finished treatment. Further research is needed to determine if the healthcare accessed by these survivors is appropriate and meets their needs.
Article
Obstetrics & Gynecology
Jayeon Kim, Brian W. Whitcomb, Brian Kwan, David Zava, Patrick M. Sluss, Andrew Dietz, Ksenya Shliakhtsitsava, Sally A. D. Romero, Loki Natarajan, H. Irene Su
Summary: There was no association found between psychosocial stress and ovarian function in adolescent and young adult cancer survivors.
HUMAN REPRODUCTION
(2021)
Review
Oncology
Karly M. Murphy, Elizabeth Siembida, Nancy Lau, Amy Berkman, Michael Roth, John M. Salsman
Summary: This study evaluated the progress of psychosocial intervention trials and health-related quality of life (HRQOL) measures for adolescents and young adults (AYA). The findings showed an increasing number of clinical trials conducted annually, but highlighted the need for improving HRQOL assessment and standardization.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2023)
Article
Medicine, General & Internal
Sooyeon Kim, Juhee Cho, Dong Wook Shin, Su-Min Jeong, Danbee Kang
Summary: This study aimed to compare the psychosocial and physical health of adolescent and young adult cancer survivors from different racial and ethnic groups. The study found that Hispanic survivors had poorer overall health, lower education levels, and lower household income compared to Non-Hispanic White survivors. African American survivors were more likely to be uncoupled and have hypertension. Asian survivors were more likely to be former/current drinkers. NHW and Asian survivors were more likely to experience psychological limitation compared to the matched general population.
Article
Oncology
Denise Riedel Lewis, Elizabeth J. Siembida, Nita L. Seibel, Ashley Wilder Smith, Angela B. Mariotto
Summary: This study analyzed long-term survival trends for cancer types with the highest mortality among AYA patients. Significant improvements in 5-year relative survival were found for some cancer types, while limited or no improvement was observed for others. The findings suggest the need for continued research focusing on specific cancer types with limited survival improvements.
Article
Oncology
Heleen Maurice-Stam, Loes M. E. van Erp, Anne Maas, Hedy A. van Oers, Leontien C. M. Kremer, Eline Van Dulmen-den Broeder, Wim J. E. Tissing, Jacqueline J. Loonen, Helena J. H. van der Pal, Laura R. Beek, Andrica C. H. de Vries, Marry M. Van den Heuvel-Eibrink, Cecile M. Ronckers, Dorine Bresters, Marloes Louwerens, Margriet Van der Heiden-van der Loo, Gea A. Huizinga, Martha A. Grootenhuis
Summary: This study aimed to compare the psychosocial development of young adult survivors of childhood cancer with a norm group of young adults from the general population. The results showed that the overall psychosocial development of the young adult survivors of childhood cancer was as favorable as the norm group, but survivors of central nervous system cancer were at risk of an unfavorable psychosocial development in all domains.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Morgan Young-Speirs, Caitlin Forbes, Michaela Patton, K. Brooke Russell, Mehak Stokoe, Kathleen Reynolds, Fiona Schulte
Summary: Survivors of childhood cancer have comparable perceived health to controls without cancer diagnosis, with pain, physical activity, and concerns related to health resources being significant predictors of perceived health. Understanding factors influencing perceived health in SCCs may help in developing interventions and further research.
Review
Medicine, General & Internal
Colene Bentley, Paulos Teckle, Lisa McQuarrie, Stuart Peacock, Shiraz El Adam
Summary: The objective of this study is to summarize peer-reviewed evidence on the effect of a cancer diagnosis on the different sources of income for individuals diagnosed with cancer during adulthood. The findings suggest that cancer's impact on survivors' income is complex and time-varying. Longitudinal studies using standardized income measures and capturing treatment type and follow-up time are needed to improve our understanding of this impact.
Article
Clinical Neurology
Raed A. Joundi, Scott B. Patten, Jeanne V. A. Williams, Eric E. Smith
Summary: Excess sleep, especially in individuals under 70 years old, may increase the risk of stroke. This study supports the current recommendation of 7-9 hours of sleep per night. Further research is needed to better understand the relationship between sleep and cerebrovascular disease.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2023)
Review
Psychology, Clinical
Daniel J. Devoe, Angela Han, Alida Anderson, Debra K. Katzman, Scott B. Patten, Andrea Soumbasis, Jordyn Flanagan, Georgios Paslakis, Ellie Vyver, Gisele Marcoux, Gina Dimitropoulos
Summary: The COVID-19 pandemic has had a negative impact on individuals with eating disorders, leading to worsening symptoms, increased anxiety and depression, and changes in body mass index (BMI). This systematic review provides important insights into the effects of COVID-19 on the physical and mental health of individuals with eating disorders.
INTERNATIONAL JOURNAL OF EATING DISORDERS
(2023)
Article
Health Care Sciences & Services
Brooke Allemang, Susan Samuel, Karina Pintson, Megan Patton, Katelyn Greer, Marcela Farias, Keighley Schofield, Kathleen C. C. Sitter, Scott B. B. Patten, Andrew S. S. Mackie, Gina Dimitropoulos
Summary: This study examines the perspectives of transition-age youth with co-occurring chronic health and mental health conditions as they prepare to exit pediatric health and mental health services. The findings reveal the interconnectedness of physical and mental health, the impact of mental health on transition readiness and self-management, and recommendations for service provision.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Clinical Neurology
Raed A. Joundi, Megan E. O'Connell, Scott Patten, Eric E. Smith
Summary: The relation between cognitive and functional decline after stroke is not well studied. This study used a comprehensive cohort to investigate the association between stroke, cognitive decline, and functional decline. The results showed that cognitive decline mediated the relationship between prior stroke and functional decline.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2023)
Article
Rehabilitation
Amanda Wurz, Delaney Duchek, Kelsey Ellis, Mannat Bansal, Marie-Eve Carrier, Lydia Tao, Laura Dyas, Linda Kwakkenbos, Brooke Levis, Ghassan El-Baalbaki, Danielle B. Rice, Yin Wu, Richard S. Henry, Laura Bustamante, Sami Harb, Shannon Hebblethwaite, Scott B. Patten, Susan J. Bartlett, John Varga, Luc Mouthon, Sarah Markham, Brett D. Thombs, S. Nicole Culos-Reed
Summary: This study explored the impact of the videoconference-based supportive care program (SPIN-CHAT program) on individuals with systemic sclerosis (SSc) during early COVID-19. Interviews with trial participants and research team members revealed that the program had positive effects on psychological health, provided SSc-specific support, created a safe space for group interaction, reduced boredom, and offered self-management skills.
DISABILITY AND REHABILITATION
(2023)
Review
Psychology, Clinical
Yin Wu, Brooke Levis, Federico M. Daray, John P. A. Ioannidis, Scott B. Patten, Pim Cuijpers, Roy C. Ziegelstein, Simon Gilbody, Felix H. Fischer, Suiqiong Fan, Ying Sun, Chen He, Ankur Krishnan, Dipika Neupane, Parash Mani Bhandari, Zelalem Negeri, Kira E. Riehm, Danielle B. Rice, Marleine Azar, Xin Wei Yan, Mahrukh Imran, Matthew J. Chiovitti, Jill T. Boruff, Dean McMillan, Lorie A. Kloda, Sarah Markham, Melissa Henry, Zahinoor Ismail, Carmen G. Loiselle, Nicholas D. Mitchell, Samir Al-Adawi, Kevin R. Beck, Anna Beraldi, Charles N. Bernstein, Birgitte Boye, Natalie Buel-Drabe, Adomas Bunevicius, Ceyhun Can, Gregory Carter, Chih-Ken Chen, Gary Cheung, Kerrie Clover, Ronan M. Conroy, Gema Costa-Requena, Daniel Cukor, Eli Dabscheck, Jennifer De Souza, Marina Downing, Anthony Feinstein, Panagiotis P. Ferentinos, Alastair J. Flint, Pamela Gallagher, Milena Gandy, Luigi Grassi, Martin Haerter, Asuncion Hernando, Melinda L. Jackson, Josef Jenewein, Nathalie Jette, Miguel Juliao, Marie Kjaergaard, Sebastian Kohler, Hans-Helmut Konig, Lalit K. R. Krishna, Yu Lee, Margrit Loebner, Wim L. Loosman, Anthony W. Love, Bernd Loewe, Ulrik F. Malt, Ruth Ann Marrie, Loreto Massardo, Yutaka Matsuoka, Anja Mehnert, Ioannis Michopoulos, Laurent Misery, Christian J. Nelson, Chong Guan Ng, Meaghan L. O'Donnell, Suzanne J. O'Rourke, Ahmet Ozturk, Alexander Pabst, Julie A. Pasco, Jurate Peceliuniene, Luis Pintor, Jennie L. Ponsford, Federico Pulido, Terence J. Quinn, Silje E. Reme, Katrin Reuter, Steffi G. Riedel-Heller, Alasdair G. Rooney, Roberto Sanchez-Gonzalez, Rebecca M. Saracino, Melanie P. J. Schellekens, Martin Scherer, Marcelo L. Schwarzbold, Vesile Senturk Cankorur, Louise Sharpe, Michael Sharpe, Sebastien Simard, Susanne Singer, Lesley Stafford, Jon Stone, Natalie A. Strobe, Serge Sultan, Antonio L. Teixeira, Istvan Tiringer, Alyna Turner, Jane Walker, Mark Walterfang, Liang-Jen Wang, Siegfried B. Weyerer, Jennifer White, Birgitt Wiese, Lana J. Williams, Lai-Yi Wong, Andrea Benedetti, Brett D. Thombsi
Summary: This study compared the screening accuracy of HADS-D and HADS-T for major depression and found no significant difference in diagnostic accuracy between the two. The shorter HADS-D would be preferred in most clinical and research settings as it not only reduces patient burden but also has equivalent diagnostic accuracy to HADS-T.
PSYCHOLOGICAL ASSESSMENT
(2023)
Article
Social Issues
Lisa K. Mundy, Louise Canterford, S. Ghazaleh Dashti, Hanafi Mohamad Husin, Ruth Beatson, Ben Edwards, George C. Patton
Summary: There is growing evidence that the COVID-19 pandemic has had significant negative effects on the mental health of adolescents. A study in Australia found that over 50% of participants reported depressive symptoms, and one-quarter reported anxiety symptoms during the pandemic. Adolescents with a history of mental health problems, school disengagement, and frequent peer victimization were at higher risk of experiencing mental health issues during the pandemic. Therefore, it is crucial for schools to prioritize the mental health and well-being of students, particularly during times of social disruption like the COVID-19 pandemic.
AUSTRALIAN JOURNAL OF SOCIAL ISSUES
(2023)
Editorial Material
Psychology, Developmental
Suneeta Monga, Riddhi Desai, Samantha J. Anthony, Paul D. Arnold, Alexa Bagnell, Boris Birmaher, Leslie Anne Campbell, Rachel Churchill, Kristin Cleverley, Darren B. Courtney, Gina Dimitropoulos, Sarah E. Hetrick, Karolin R. Krause, Lidwine B. Mokkink, Scott B. Patten, Megan C. Patton, Matthew J. Prebeg, Beth K. Potter, Erin Romanchych, Jai L. Shah, Maureen Smith, S. Evelyn Stewart, Peter Szatmari, Andrea C. Tricco, Peter Tugwell, John T. Walkup, Vivian A. Welch, Bonnie T. Zima, Nancy J. Butcher, Martin Offringa
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Clinical Neurology
Elisabet Rodriguez Llorian, Wei Zhang, Amir Khakban, Kristina Michaux, Scott Patten, Anthony Traboulsee, Jiwon Oh, Shannon Kolind, Alexandre Prat, Roger Tam, Larry D. Lynd
Summary: This study examines the impact of multiple sclerosis (MS) on productivity loss and employment status. Using baseline data from the Canadian Prospective Cohort Study to Understand Progression in Multiple Sclerosis (CanProCo), the study measures MS-related productivity loss and investigates associated factors. The findings show that both employed and unemployed individuals with MS experience significant productivity loss, and modifiable factors such as disease-modifying therapies, fatigue, and cognitive processing speed impact productivity loss and employment status. Targeting these factors is likely to improve work productivity and permanence of MS patients in the workforce.
MULTIPLE SCLEROSIS JOURNAL
(2023)
Article
Psychology, Clinical
Sasha Gorrell, Elizabeth K. Hughes, George C. Patton, Susan M. Sawyer, Daniel Le Grange, Jessica A. Kerr
Summary: This study aimed to determine the prevalence rates of weight-control exercise in adolescents and examine the influence of gender and weight status on such exercise. The findings suggest that boys with overweight or obesity have a higher likelihood of engaging in weight-control exercise compared to girls. Accurate identification of at-risk adolescents should consider gender and weight status when defining excessive weight-control exercise.
Article
Medical Informatics
Michelle Lu, Rachel E. Crooks, Diana F. Pricop, Emily Cox, Beatrice Anghelescu, Mark Hamilton, Davide Martino, Veronica Bruno, Colin B. Josephson, Scott Patten, Eric E. Smith, Pamela Roach
Summary: This study aimed to explore barriers and facilitators of virtual care from the perspective of neurological and psychiatric patients. One-on-one interviews were conducted remotely using telephone and online video teleconferencing, with a total of 57 participants. The study found that virtual care can increase accessibility and efficiency for patients and providers, indicating its potential for ongoing use in the delivery of clinical care. Patients perceived virtual care as an acceptable mode of healthcare delivery, but there remains a continued need for relationship-building between care providers and patients.
HEALTH AND TECHNOLOGY
(2023)
Article
Clinical Neurology
Dhruv Jain, Charles N. Bernstein, Lesley A. Graff, Scott B. Patten, James M. Bolton, John D. Fisk, Carol Hitchon, James J. Marriott, Ruth Ann Marrie
Summary: This study compared the prevalence of pain and the association between pain and pain interference, as well as social participation, in different subtypes of multiple sclerosis. The results showed that pain was common among all participants, with no differences between subtypes. However, individuals with progressive multiple sclerosis reported higher pain interference and lower social participation compared to those with relapsing-remitting multiple sclerosis.
MULTIPLE SCLEROSIS JOURNAL-EXPERIMENTAL TRANSLATIONAL AND CLINICAL
(2023)
Meeting Abstract
Neurosciences
Maya Sohn, Jaeden Cole, Ashley Harris, Signe Bray, Scott B. Patten, Alexander McGirr
BIOLOGICAL PSYCHIATRY
(2023)
Meeting Abstract
Neurosciences
Marilena DeMayo, Jaeden Cole, Maya Sohn, Signe Bray, Ashley Harris, Scott B. Patten, Alexander McGirr
BIOLOGICAL PSYCHIATRY
(2023)
Article
Health Care Sciences & Services
Andrew J. Stewart, Scott B. Patten, Kirsten M. Fiest, Tyler S. Williamson, James P. Wick, Paul E. Ronksley
Summary: Schizophrenia patients have diverse healthcare needs, but little research has been done to understand the heterogeneity among them. This study used a data-driven approach to identify subgroups of high-cost schizophrenia patients, which can inform interventions and resource allocation. The findings provide insights into different patient groups and their clinical profiles, facilitating policy-making and cost reduction.
HEALTH SERVICES INSIGHTS
(2023)
