Optogenetics: Applications in psychiatric research

Synapse pathology and translational applications for schizophrenia

(2017) Akiko Hayashi-Takagi   NEUROSCIENCE RESEARCH

Natural Photoreceptors as a Source of Fluorescent Proteins, Biosensors, and Optogenetic Tools

(2015) Daria M. Shcherbakova et al.   Annual Review of Biochemistry

Activating positive memory engrams suppresses depression-like behaviour

(2015) Steve Ramirez et al.   NATURE

Labelling and optical erasure of synaptic memory traces in the motor cortex

(2015) Akiko Hayashi-Takagi et al.   NATURE

Basomedial amygdala mediates top-down control of anxiety and fear

(2015) Avishek Adhikari et al.   NATURE

Mechanism of Deep Brain Stimulation

(2015) Satomi Chiken et al.   NEUROSCIENTIST

Refining deep brain stimulation to emulate optogenetic treatment of synaptic pathology

(2015) M. Creed et al.   SCIENCE

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

Near-infrared (NIR) up-conversion optogenetics

(2015) Shoko Hososhima et al.   Scientific Reports

Inhibitory luminopsins: genetically-encoded bioluminescent opsins for versatile, scalable and hardware-independent optogenetic inhibition

(2015) Jack K. Tung et al.   Scientific Reports

Contrasting forms of cocaine-evoked plasticity control components of relapse

(2014) Vincent Pascoli et al.   NATURE

PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence

(2014) A. Hayashi-Takagi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetics, visual prosthesis and electrostimulation for retinal dystrophies

(2013) Sunir J. Garg et al.   CURRENT OPINION IN OPHTHALMOLOGY

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

(2013) John Y Lin et al.   NATURE NEUROSCIENCE

Light-Emitting Channelrhodopsins for Combined Optogenetic and Chemical-Genetic Control of Neurons

(2013) Ken Berglund et al.   PLoS One

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

(2013) S. E. Ahmari et al.   SCIENCE

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

(2013) Esther Krook-Magnuson et al.   Nature Communications

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

(2012) Kay M. Tye et al.   NATURE

Spatiotemporal control of gene expression by a light-switchable transgene system

(2012) Xue Wang et al.   NATURE METHODS

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Function, structure and mechanism of bacterial photosensory LOV proteins

(2011) Julien Herrou et al.   NATURE REVIEWS MICROBIOLOGY

Dendritic Spines and Distributed Circuits

(2011) Rafael Yuste   NEURON

Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

(2011) David A. Lewis et al.   TRENDS IN NEUROSCIENCES

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Method of the Year 2010

(2010)   NATURE METHODS

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

(2010) Akiko Hayashi-Takagi et al.   NATURE NEUROSCIENCE

Abnormal neural oscillations and synchrony in schizophrenia

(2010) Peter J. Uhlhaas et al.   NATURE REVIEWS NEUROSCIENCE

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

(2010) I. B. Witten et al.   SCIENCE

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE