Journal
PROTEOMICS
Volume 17, Issue 15-16, Pages -Publisher
WILEY
DOI: 10.1002/pmic.201600477
Keywords
Extracellular vesicles; MS; Toxoplasma gondii; Toxoplasma-infected cell
Funding
- Programa Estrategico de Apoio a Pesquisa em Saude (PAPES)
- CNPq Universal [21465213.5.0000.5248]
- CAPES
Ask authors/readers for more resources
Toxoplasma gondii infects a wide range of hosts worldwide, including humans and domesticated animals causing toxoplasmosis disease. Recently, exosomes, small extracellular vesicles (EV) that contain nucleic acids, proteins, and lipids derived from their original cells were linked with disease protection. The effect of EVs derived from T. gondii on the immune response and its relevance in a physiological context is unknown. Here we disclose the first proteomic profiling of T. gondii EVs compared to EVs isolated from a human foreskin fibroblast infected cell line cultured in a vesicle- free medium. Our results reveal a broad range of canonical exosomes proteins. Data are available via ProteomeXchange with the identifier PXD004895.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available