Breaking up and making up: The secret life of the vacuolar H+ -ATPase

Crystal structure of yeast V1‐ATPase in the autoinhibited state

(2016) Rebecca A Oot et al.   EMBO JOURNAL

Structure of the Lipid Nanodisc-reconstituted Vacuolar ATPase Proton Channel

(2016) Nicholas J. Stam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase

(2016) Mohammad T. Mazhab-Jafari et al.   NATURE

Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore

(2016) Sergio Couoh-Cardel et al.   Scientific Reports

The membrane domain of vacuolar H+ATPase: a crucial player in neurotransmitter exocytotic release

(2015) Nicolas Morel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Interactions and Cellular Itinerary of the Yeast RAVE (Regulator of the H+-ATPase of Vacuolar and Endosomal Membranes) Complex

(2015) Anne M. Smardon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino Acid Availability Modulates Vacuolar H+-ATPase Assembly

(2015) Laura A. Stransky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Affinity Purification and Structural Features of the Yeast Vacuolar ATPase VoMembrane Sector

(2015) Sergio Couoh-Cardel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase

(2015) Jianhua Zhao et al.   NATURE

Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase

(2015) Matteo Allegretti et al.   NATURE

Structure of the Vacuolar H + -ATPase Rotary Motor Reveals New Mechanistic Insights

(2015) Shaun Rawson et al.   STRUCTURE

Reversible disassembly of the yeast V-ATPase revisited underin vivoconditions

(2014) Katharina Tabke et al.   BIOCHEMICAL JOURNAL

Saccharomyces cerevisiae Vacuolar H+-ATPase Regulation by Disassembly and Reassembly: One Structure and Multiple Signals

(2014) Karlett J. Parra et al.   EUKARYOTIC CELL

Novel techniques in the development of osteoporosis drug therapy: the osteoclast ruffled-border vacuolar H+-ATPase as an emerging target

(2014) Norbert Kartner et al.   Expert Opinion on Drug Discovery

Crystal Structure of Subunits D and F in Complex Gives Insight into Energy Transmission of the Eukaryotic V-ATPase fromSaccharomyces cerevisiae

(2014) Asha Manikkoth Balakrishna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yeast Phosphofructokinase-1 Subunit Pfk2p Is Necessary for pH Homeostasis and Glucose-dependent Vacuolar ATPase Reassembly

(2014) Chun-Yuan Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new life for an old pump: V-ATPase and neurotransmitter release

(2014) Stefano Vavassori et al.   JOURNAL OF CELL BIOLOGY

Basic Properties of Rotary Dynamics of the Molecular MotorEnterococcus hiraeV1-ATPase

(2013) Yoshihiro Minagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RAVE complex is an isoform-specific V-ATPase assembly factor in yeast

(2013) Anne M. Smardon et al.   MOLECULAR BIOLOGY OF THE CELL

Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures

(2013) Satoshi Arai et al.   NATURE

Biochemical and Biophysical Properties of Interactions between Subunits of the Peripheral Stalk Region of Human V-ATPase

(2013) Suhaila Rahman et al.   PLoS One

Rotational catalysis in proton pumping ATPases: From E. coli F-ATPase to mammalian V-ATPase

(2012) Masamitsu Futai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Disruption of the V-ATPase Functionality as a Way to Uncouple Bone Formation and Resorption - A Novel Target for Treatment of Osteoporosis

(2012) C. S. Thudium et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Targeting Reversible Disassembly as a Mechanism of Controlling V-ATPase Activity

(2012) Patricia M. Kane   CURRENT PROTEIN & PEPTIDE SCIENCE

Epidermal Growth Factor-induced Vacuolar (H+)-ATPase Assembly

(2012) Yanqing Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subunit Interactions at the V1-VoInterface in Yeast Vacuolar ATPase

(2012) Rebecca A. Oot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the vacuolar-type ATPase from Saccharomyces cerevisiae at 11-Å resolution

(2012) Samir Benlekbir et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structure of the Yeast Vacuolar ATPase Heterotrimeric EGChead Peripheral Stalk Complex

(2012) Rebecca A. Oot et al.   STRUCTURE

Vacuolar H + -ATPase Works in Parallel with the HOG Pathway To Adapt Saccharomyces cerevisiae Cells to Osmotic Stress

(2011) Sheena Claire Li et al.   EUKARYOTIC CELL

Definition of Membrane Topology and Identification of Residues Important for Transport in Subunit a of the Vacuolar ATPase

(2011) Masashi Toei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Cytoplasmic N-Terminal Domain of Subunit I, a Homolog of Subunit a, of V-ATPase

(2011) Sankaranarayanan Srinivasan et al.   JOURNAL OF MOLECULAR BIOLOGY

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

(2011) D. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural divergence of the rotary ATPases

(2011) Stephen P. Muench et al.   QUARTERLY REVIEWS OF BIOPHYSICS

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Resolving stepping rotation in Thermus thermophilus H+-ATPase/synthase with an essentially drag-free probe

(2011) Shou Furuike et al.   Nature Communications

Regulation and Isoform Function of the V-ATPases

(2010) Masashi Toei et al.   BIOCHEMISTRY

Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase

(2010) Reinhard Dechant et al.   EMBO JOURNAL

Domain Characterization and Interaction of the Yeast Vacuolar ATPase Subunit C with the Peripheral Stator Stalk Subunits E and G

(2010) Rebecca A. Oot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Vacuolar Proton-translocating ATPase Activity and Assembly by Extracellular pH

(2010) Theodore T. Diakov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy

(2010) Enrico P Spugnini et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

The Vacuolar Proton Pump, V-ATPase, Is Required for Notch Signaling and Endosomal Trafficking in Drosophila

(2009) Yan Yan et al.   DEVELOPMENTAL CELL

Subunit Interactions and Requirements for Inhibition of the Yeast V1-ATPase

(2009) Heba Diab et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-electron Microscopy of the Vacuolar ATPase Motor Reveals its Mechanical and Regulatory Complexity

(2009) Stephen P. Muench et al.   JOURNAL OF MOLECULAR BIOLOGY

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function

(2008) Vladimir Marshansky et al.   CURRENT OPINION IN CELL BIOLOGY

Function and Subunit Interactions of the N-terminal Domain of Subunit a (Vph1p) of the Yeast V-ATPase

(2008) Jie Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Yeast Vacuolar ATPase

(2008) Zhenyu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP Hydrolysis and Synthesis of a Rotary Motor V-ATPase fromThermus thermophilus

(2008) Masahiro Nakano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ras/cAMP/Protein Kinase A Pathway Regulates Glucose-dependent Assembly of the Vacuolar (H+)-ATPase in Yeast

(2008) Sarah Bond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Different Conformation for EGC Stator Subcomplex in Solution and in the Assembled Yeast V-ATPase: Possible Implications for Regulatory Disassembly

(2008) Meikel Diepholz et al.   STRUCTURE