Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation

Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma

(2016) Rana Rais et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bioanalysis of 6-diazo-5-oxo-l-norleucine in plasma and brain by ultra-performance liquid chromatography mass spectrometry

(2015) Jesse Alt et al.   ANALYTICAL BIOCHEMISTRY

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

(2015) Giorgia Mori et al.   CHEMISTRY & BIOLOGY

Human γ-Glutamyl Transpeptidase 1

(2015) Simon S. Terzyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reviving Lonidamine and 6-Diazo-5-oxo-L-norleucine to Be Used in Combination for Metabolic Cancer Therapy

(2015) Diana Cervantes-Madrid et al.   Biomed Research International

Structural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA)

(2014) K. Thangavelu et al.   Scientific Reports

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma

(2014) Marina Tuzova et al.   Frontiers in Pharmacology

Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors

(2013) Stephanie Wickham et al.   BIOCHEMICAL JOURNAL

Novel Insights into Eukaryotic γ-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme

(2013) Matthew B. West et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autocatalytic Cleavage of Human γ-Glutamyl Transpeptidase Is Highly Dependent onN-Glycosylation at Asparagine 95

(2011) Matthew B. West et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divergent effects of compounds on the hydrolysis and transpeptidation reactions of γ-glutamyl transpeptidase

(2011) Stephanie Wickham et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Preventive Effect of GGsTop, a Novel and Selective  -Glutamyl Transpeptidase Inhibitor, on Ischemia/Reperfusion-Induced Renal Injury in Rats

(2011) S. Yamamoto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Regulation of active site coupling in glutamine-dependent NAD+ synthetase

(2009) Nicole LaRonde-LeBlanc et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional and Structural Characterization of Four Glutaminases from Escherichia coli and Bacillus subtilis†

(2008) Greg Brown et al.   BIOCHEMISTRY

Crystal Structures of Escherichia coli γ-Glutamyltranspeptidase in Complex with Azaserine and Acivicin: Novel Mechanistic Implication for Inhibition by Glutamine Antagonists

(2008) Kei Wada et al.   JOURNAL OF MOLECULAR BIOLOGY