Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily

(2016) Oliver Daumke et al.   BIOPOLYMERS

Structures of human mitofusin 1 provide insight into mitochondrial tethering

(2016) Yuanbo Qi et al.   JOURNAL OF CELL BIOLOGY

Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease

(2016) Danielle Pilla-Moffett et al.   JOURNAL OF MOLECULAR BIOLOGY

Fusion of the endoplasmic reticulum by membrane-bound GTPases

(2016) Junjie Hu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases

(2016) Nathalie Britzen-Laurent et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A mathematical model explains saturating axon guidance responses to molecular gradients

(2016) Huyen Nguyen et al.   eLife

Interferon-inducible GTPases in cell autonomous and innate immunity

(2015) Etienne Meunier et al.   CELLULAR MICROBIOLOGY

Guanylate Binding Proteins Enable Rapid Activation of Canonical and Noncanonical Inflammasomes in Chlamydia-Infected Macrophages

(2015) Ryan Finethy et al.   INFECTION AND IMMUNITY

Cis and trans interactions between atlastin molecules during membrane fusion

(2015) Tina Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ras moves to stay in place

(2015) Malte Schmick et al.   TRENDS IN CELL BIOLOGY

Triphosphate Induced Dimerization of Human Guanylate Binding Protein 1 Involves Association of the C-Terminal Helices: A Joint Double Electron–Electron Resonance and FRET Study

(2014) Tobias Vöpel et al.   BIOCHEMISTRY

Structural Requirements for the Antiviral Activity of the Human MxA Protein against Thogoto and Influenza A Virus

(2014) Corinna Patzina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission

(2014) Patrick J. Macdonald et al.   MOLECULAR BIOLOGY OF THE CELL

GTP-Dependent Membrane Fusion

(2013) James A. McNew et al.   Annual Review of Cell and Developmental Biology

Amphisomal Route of MHC Class I Cross-Presentation in Bacteria-Infected Dendritic Cells

(2013) D. Fiegl et al.   JOURNAL OF IMMUNOLOGY

Gamma Interferon-Induced Guanylate Binding Protein 1 Is a Novel Actin Cytoskeleton Remodeling Factor

(2013) N. Ostler et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy restrictsChlamydia trachomatisgrowth in human macrophages via IFNG-inducible guanylate binding proteins

(2012) Munir A. Al-Zeer et al.   Autophagy

Mechanistic perspective of mitochondrial fusion: Tubulation vs. fragmentation

(2012) Mafalda Escobar-Henriques et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction

(2012) Sandrine Morlot et al.   CELL

The GTPase Activity of Murine Guanylate-binding Protein 2 (mGBP2) Controls the Intracellular Localization and Recruitment to the Parasitophorous Vacuole ofToxoplasma gondii

(2012) Elisabeth Kravets et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immobilization of Biotinylated hGBP1 in a Defined Orientation on Surfaces Is Crucial for Uniform Interaction with Analyte Proteins and Catalytic Activity

(2012) Adrian Syguda et al.   LANGMUIR

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals

(2012) A. R. Shenoy et al.   SCIENCE

Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function

(2011) Song Gao et al.   IMMUNITY

Dimerization and Its Role in GMP Formation by Human Guanylate Binding Proteins

(2010) Nazish Abdullah et al.   BIOPHYSICAL JOURNAL

Purification of the CaaX-modified, dynamin-related large GTPase hGBP1 by coexpression with farnesyltransferase

(2010) Julia M. Fres et al.   JOURNAL OF LIPID RESEARCH

Mechanism of GTPase-Activity-Induced Self-Assembly of Human Guanylate Binding Protein 1

(2010) Tobias Vöpel et al.   JOURNAL OF MOLECULAR BIOLOGY

Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical Manner

(2010) Nathalie Britzen-Laurent et al.   PLoS One

Nucleotide dependent cysteine reactivity of hGBP1 uncovers a domain movement during GTP hydrolysis

(2009) Tobias Vöpel et al.   FEBS LETTERS

The Phagosomal Proteome in Interferon-γ-Activated Macrophages

(2009) Matthias Trost et al.   IMMUNITY

Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ

(2009) Illya Tietzel et al.   PLoS One