Dissecting the genetic and metabolic mechanisms of adaptation to the knockout of a major metabolic enzyme inEscherichia coli

Comprehensive analysis of glucose and xylose metabolism in Escherichia coli under aerobic and anaerobic conditions by 13 C metabolic flux analysis

(2017) Jacqueline E. Gonzalez et al.   METABOLIC ENGINEERING

Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution

(2017) Hemanshu Mundhada et al.   METABOLIC ENGINEERING

Fast growth phenotype of E. coli K-12 from adaptive laboratory evolution does not require intracellular flux rewiring

(2017) Christopher P. Long et al.   METABOLIC ENGINEERING

Enzyme I facilitates reverse flux from pyruvate to phosphoenolpyruvate in Escherichia coli

(2017) Christopher P. Long et al.   Nature Communications

Measuring the Composition and Stable-Isotope Labeling of Algal Biomass Carbohydrates via Gas Chromatography/Mass Spectrometry

(2016) Brian O. McConnell et al.   ANALYTICAL CHEMISTRY

Characterization of physiological responses to 22 gene knockouts in Escherichia coli central carbon metabolism

(2016) Christopher P. Long et al.   METABOLIC ENGINEERING

Optimal tracers for parallel labeling experiments and 13 C metabolic flux analysis: A new precision and synergy scoring system

(2016) Scott B. Crown et al.   METABOLIC ENGINEERING

13 C metabolic flux analysis of microbial and mammalian systems is enhanced with GC-MS measurements of glycogen and RNA labeling

(2016) Christopher P. Long et al.   METABOLIC ENGINEERING

13 C metabolic flux analysis of the extremely thermophilic, fast growing, xylose-utilizing Geobacillus strain LC300

(2016) Lauren T. Cordova et al.   METABOLIC ENGINEERING

Evolution of E. coli on [U-13C]Glucose Reveals a Negligible Isotopic Influence on Metabolism and Physiology

(2016) Troy E. Sandberg et al.   PLoS One

Global Rebalancing of Cellular Resources by Pleiotropic Point Mutations Illustrates a Multi-scale Mechanism of Adaptive Evolution

(2016) Jose Utrilla et al.   Cell Systems

Improving prediction fidelity of cellular metabolism with kinetic descriptions

(2015) Anupam Chowdhury et al.   CURRENT OPINION IN BIOTECHNOLOGY

Integrated 13 C-metabolic flux analysis of 14 parallel labeling experiments in Escherichia coli

(2015) Scott B. Crown et al.   METABOLIC ENGINEERING

Transhydrogenase Promotes the Robustness and Evolvability of E. coli Deficient in NADPH Production

(2015) Hsin-Hung Chou et al.   PLoS Genetics

Quantifying Biomass Composition by Gas Chromatography/Mass Spectrometry

(2014) Christopher P. Long et al.   ANALYTICAL CHEMISTRY

Use of Adaptive Laboratory Evolution To Discover Key Mutations Enabling Rapid Growth of Escherichia coli K-12 MG1655 on Glucose Minimal Medium

(2014) Ryan A. LaCroix et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic flux analysis of Escherichia coli knockouts: lessons from the Keio collection and future outlook

(2014) Christopher P Long et al.   CURRENT OPINION IN BIOTECHNOLOGY

A kinetic model of Escherichia coli core metabolism satisfying multiple sets of mutant flux data

(2014) Ali Khodayari et al.   METABOLIC ENGINEERING

The Bacterial Phosphoenolpyruvate:Carbohydrate Phosphotransferase System: Regulation by Protein Phosphorylation and Phosphorylation-Dependent Protein-Protein Interactions

(2014) Josef Deutscher et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Evolution of Escherichia coli to 42 °C and Subsequent Genetic Engineering Reveals Adaptive Mechanisms and Novel Mutations

(2014) Troy E. Sandberg et al.   MOLECULAR BIOLOGY AND EVOLUTION

Metabolic engineering and transhydrogenase effects on NADPH availability inescherichia coli

(2013) Joanna Jan et al.   BIOTECHNOLOGY PROGRESS

COMPLETE-MFA: Complementary parallel labeling experiments technique for metabolic flux analysis

(2013) Robert W. Leighty et al.   METABOLIC ENGINEERING

Adaptive laboratory evolution – principles and applications for biotechnology

(2013) Martin Dragosits et al.   Microbial Cell Factories

Functioning of a metabolic flux sensor in Escherichia coli

(2013) K. Kochanowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-Term Dynamics of Adaptation in Asexual Populations

(2013) M. J. Wiser et al.   SCIENCE

Current knowledge of the Escherichia coli phosphoenolpyruvate–carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and product formation

(2012) Adelfo Escalante et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Visualizing evolution in real time to determine the molecular mechanisms of n-butanol tolerance in Escherichia coli

(2012) Luis H. Reyes et al.   METABOLIC ENGINEERING

Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using 13 C metabolic flux analysis

(2012) Yuki Usui et al.   Microbial Cell Factories

In silico method for modelling metabolism and gene product expression at genome scale

(2012) Joshua A. Lerman et al.   Nature Communications

RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations

(2012) Joonhoon Kim et al.   GENOME BIOLOGY

Dispensability of Escherichia coli's latent pathways

(2011) S. P. Cornelius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive Evolution of Escherichia coli K-12 MG1655 during Growth on a Nonnative Carbon Source, L-1,2-Propanediol

(2010) D.-H. Lee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

13C-metabolic flux analysis for batch culture ofEscherichia coliand itspykandpgigene knockout mutants based on mass isotopomer distribution of intracellular metabolites

(2010) Yoshihiro Toya et al.   BIOTECHNOLOGY PROGRESS

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress

(2010) Takaaki Horinouchi et al.   BMC GENOMICS

Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli

(2010) Shota Atsumi et al.   Molecular Systems Biology

Genetic Basis of Growth Adaptation of Escherichia coli after Deletion of pgi, a Major Metabolic Gene

(2010) Pep Charusanti et al.   PLoS Genetics

Genome evolution and adaptation in a long-term experiment with Escherichia coli

(2009) Jeffrey E. Barrick et al.   NATURE

Whole-genome resequencing of Escherichia coli K-12 MG1655 undergoing short-term laboratory evolution in lactate minimal media reveals flexible selection of adaptive mutations

(2009) Tom M Conrad et al.   GENOME BIOLOGY

Genome-scale reconstruction of the Lrp regulatory network in Escherichia coli

(2008) B.-K. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA