ERAP1association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations

A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers

(2016) Masaki Takeuchi et al.   ANNALS OF THE RHEUMATIC DISEASES

Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis

(2016) Chikashi Terao et al.   Annual Review of Genomics and Human Genetics

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

(2016) David Ellinghaus et al.   NATURE GENETICS

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

(2015) Adrian Cortes et al.   Nature Communications

Functionally distinctERAP1allotype combinations distinguish individuals with Ankylosing Spondylitis

(2014) Emma Reeves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

(2014) Jared O'Connell et al.   PLoS Genetics

Naturally Occurring ERAP1 Haplotypes Encode Functionally Distinct Alleles with Fine Substrate Specificity

(2013) E. Reeves et al.   JOURNAL OF IMMUNOLOGY

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

(2013) Adrian Cortes et al.   NATURE GENETICS

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

(2011) G. Kochan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis

(2009) F. W. L. Tsui et al.   ANNALS OF THE RHEUMATIC DISEASES

Investigating the genetic association between ERAP1 and ankylosing spondylitis

(2009) David Harvey et al.   HUMAN MOLECULAR GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics