ERRα induces H3K9 demethylation by LSD1 to promote cell invasion

miR-135a Inhibits the Invasion of Cancer Cells via Suppression of ERRα

(2016) Violaine Tribollet et al.   PLoS One

Lysine-specific demethylase 1 mediates epidermal growth factor signaling to promote cell migration in ovarian cancer cells

(2015) Genbao Shao et al.   Scientific Reports

LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition

(2015) Satoi Nagasawa et al.   PLoS One

High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients

(2014) Remco S Derr et al.   BMC CANCER

Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

(2014) Juliette Sailland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LSD1 promotes oxidative metabolism of white adipose tissue

(2014) Delphine Duteil et al.   Nature Communications

Lysine-Specific Demethylase 1 Has Dual Functions as a Major Regulator of Androgen Receptor Transcriptional Activity

(2014) Changmeng Cai et al.   Cell Reports

Reconstruction of Quaternary Structure from X-ray Scattering by Equilibrium Mixtures of Biological Macromolecules

(2013) Maxim V. Petoukhov et al.   BIOCHEMISTRY

Molecular and Genetic Crosstalks between mTOR and ERRα Are Key Determinants of Rapamycin-Induced Nonalcoholic Fatty Liver

(2013) Cédric Chaveroux et al.   Cell Metabolism

Decoding a Signature-Based Model of Transcription Cofactor Recruitment Dictated by Cardinal Cis-Regulatory Elements in Proximal Promoter Regions

(2013) Christopher Benner et al.   PLoS Genetics

Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion

(2012) G. Ferrari-Amorotti et al.   CANCER RESEARCH

The Corepressor NCoR1 Antagonizes PGC-1  and Estrogen-Related Receptor   in the Regulation of Skeletal Muscle Function and Oxidative Metabolism

(2012) J. Perez-Schindler et al.   MOLECULAR AND CELLULAR BIOLOGY

Enhancer decommissioning by LSD1 during embryonic stem cell differentiation

(2012) Warren A. Whyte et al.   NATURE

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Dual Function of ERR  in Breast Cancer and Bone Metastasis Formation: Implication of VEGF and Osteoprotegerin

(2011) A. Fradet et al.   CANCER RESEARCH

ERRs and cancers: Effects on metabolism and on proliferation and migration capacities

(2011) Stéphanie Bianco et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells

(2011) Antonio Adamo et al.   NATURE CELL BIOLOGY

Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation

(2011) Shigeaki Kato et al.   TRENDS IN BIOCHEMICAL SCIENCES

Identification of biomarkers associated with metastastic breast cancer to bone by immunohistochemistry on tissue microarrays.

(2010) I Nasir et al.   CANCER RESEARCH

WNT11 Expression Is Induced by Estrogen-Related Receptor   and  -Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration

(2010) M. A. Dwyer et al.   CANCER RESEARCH

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-α target gene activation by regulating lysine demethylase 1 specificity

(2010) Sujit S Nair et al.   EMBO REPORTS

The homeobox protein Prox1 is a negative modulator of ERR /PGC-1  bioenergetic functions

(2010) A. Charest-Marcotte et al.   GENES & DEVELOPMENT

Epigenetic regulation of cancer growth by histone demethylases

(2010) Soyoung Lim et al.   INTERNATIONAL JOURNAL OF CANCER

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

(2010) Shinya Hayami et al.   INTERNATIONAL JOURNAL OF CANCER

Histone Demethylase LSD1 Regulates Adipogenesis

(2010) Melina M. Musri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of histone H3T6 by PKCβI controls demethylation at histone H3K4

(2010) Eric Metzger et al.   NATURE

Deconstructing repression: evolving models of co-repressor action

(2010) Valentina Perissi et al.   NATURE REVIEWS GENETICS

Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition

(2010) T Lin et al.   ONCOGENE

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer

(2009) Yan Wang et al.   CELL

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

(2008) Vincent Giguère   ENDOCRINE REVIEWS

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

(2008) P. A.C. Cloos et al.   GENES & DEVELOPMENT

DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression

(2008) B. Perillo et al.   SCIENCE

ERRα: a metabolic function for the oldest orphan

(2008) Josep A. Villena et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM