Proton movement and coupling in the POT family of peptide transporters

Shared Molecular Mechanisms of Membrane Transporters

(2016) David Drew et al.   Annual Review of Biochemistry

Multiscale Simulations Reveal Key Aspects of the Proton Transport Mechanism in the ClC-ec1 Antiporter

(2016) Sangyun Lee et al.   BIOPHYSICAL JOURNAL

Multiscale simulations reveal key features of the proton-pumping mechanism in cytochromecoxidase

(2016) Ruibin Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular insights into proton coupled peptide transport in the PTR family of oligopeptide transporters

(2015) Simon Newstead   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Structure of LacY with an α-substituted galactoside: Connecting the binding site to the protonation site

(2015) Hemant Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gating Topology of the Proton-Coupled Oligopeptide Symporters

(2015) Philip W. Fowler et al.   STRUCTURE

Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters

(2014) J. A. Lyons et al.   EMBO REPORTS

Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1

(2014) Joanne L. Parker et al.   NATURE

Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2

(2014) Fatma Guettou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiscale simulation reveals a multifaceted mechanism of proton permeation through the influenza A M2 proton channel

(2014) Ruibin Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter

(2014) Joanne L Parker et al.   eLife

Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY

(2013) Lukas S. Stelzl et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolutionary mix-and-match with MFS transporters

(2013) M. G. Madej et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Water access points and hydration pathways in CLC H+/Cl−transporters

(2013) Wei Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT

(2013) S. Doki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A unified nomenclature of NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER family members in plants

(2013) Sophie Léran et al.   TRENDS IN PLANT SCIENCE

Analysing the substrate multispecificity of a proton-coupled oligopeptide transporter using a dipeptide library

(2013) Keisuke Ito et al.   Nature Communications

Alternating access mechanism in the POT family of oligopeptide transporters

(2012) Nicolae Solcan et al.   EMBO JOURNAL

The major facilitator superfamily (MFS) revisited

(2012) Vamsee S. Reddy et al.   FEBS Journal

Apo-intermediate in the transport cycle of lactose permease (LacY)

(2012) M. G. Madej et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton-Coupled Dynamics in Lactose Permease

(2012) Magnus Andersson et al.   STRUCTURE

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2

(2010) Simon Newstead et al.   EMBO JOURNAL

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu

(2010) Stefan Grimme et al.   JOURNAL OF CHEMICAL PHYSICS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY

Protonation and sugar binding to LacY

(2008) Irina N. Smirnova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA