Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage

Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells

(2016) Rui Monteiro et al.   DEVELOPMENTAL CELL

Bone Morphogenetic Proteins

(2016) Takenobu Katagiri et al.   Cold Spring Harbor Perspectives in Biology

Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells

(2016) Céline Souilhol et al.   Nature Communications

EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta

(2016) Inn-Inn Chen et al.   Scientific Reports

Transcription factor-mediated reprogramming toward hematopoietic stem cells

(2015) W. Ebina et al.   EMBO JOURNAL

Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2

(2015) F. Liu et al.   EMBO REPORTS

BMP signalling: agony and antagony in the family

(2015) Derek P. Brazil et al.   TRENDS IN CELL BIOLOGY

Developmental hematopoiesis: Ontogeny, genetic programming and conservation

(2014) Aldo Ciau-Uitz et al.   EXPERIMENTAL HEMATOLOGY

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

(2014) Christopher M Sturgeon et al.   NATURE BIOTECHNOLOGY

Xenbase, the Xenopus model organism database; new virtualized system, data types and genomes

(2014) J. Brad Karpinka et al.   NUCLEIC ACIDS RESEARCH

FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway

(2014) Claire Pouget et al.   Nature Communications

Optimizing Autologous Stem Cell Mobilization Strategies to Improve Patient Outcomes: Consensus Guidelines and Recommendations

(2013) Sergio Giralt et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

BMP-mediated specification of the erythroid lineage suppresses endothelial development in blood island precursors

(2013) C. T. Myers et al.   BLOOD

A short history of hemogenic endothelium

(2013) Gemma Swiers et al.   BLOOD CELLS MOLECULES AND DISEASES

VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus

(2013) A. Ciau-Uitz et al.   DEVELOPMENT

Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification

(2013) Amy Leung et al.   DEVELOPMENTAL CELL

Endothelio-Mesenchymal Interaction Controls runx1 Expression and Modulates the notch Pathway to Initiate Aortic Hematopoiesis

(2013) Charlotte Richard et al.   DEVELOPMENTAL CELL

miR-142-3p Controls the Specification of Definitive Hemangioblasts during Ontogeny

(2013) Rachael Nimmo et al.   DEVELOPMENTAL CELL

Gata2cis-element is required for hematopoietic stem cell generation in the mammalian embryo

(2013) Xin Gao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gata2is required for HSC generation and survival

(2013) Emma de Pater et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcriptional programme controlled by Runx1 during early embryonic blood development

(2012) Yosuke Tanaka et al.   DEVELOPMENTAL BIOLOGY

Application of Small Organic Molecules Reveals Cooperative TGFβ and BMP Regulation of Mesothelial Cell Behaviors

(2011) Emily E. Cross et al.   ACS Chemical Biology

Noggin

(2011) Carola Krause et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of Smad signaling in hematopoiesis and translational hematology

(2011) U Blank et al.   LEUKEMIA

Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2

(2010) S. Mitola et al.   BLOOD

Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture

(2010) S. Singbrant et al.   BLOOD

Vegf regulates embryonic erythroid development through Gata1 modulation

(2010) B. Drogat et al.   BLOOD

Tel1/ETV6 Specifies Blood Stem Cells through the Agency of VEGF Signaling

(2010) Aldo Ciau-Uitz et al.   DEVELOPMENTAL CELL

Genetic control of hematopoietic development in Xenopus and zebrafish

(2010) Aldo Ciau-Uitz et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Hematopoietic Stem Cell TransplantationA Global Perspective

(2010) Alois Gratwohl   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Wnt/ -catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo

(2010) H. T. Tran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In VivoStructure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

(2009) Jijun Hao et al.   ACS Chemical Biology

BMP4 regulates the hematopoietic stem cell niche

(2009) D. C. Goldman et al.   BLOOD

Hedgehog and Bmp Polarize Hematopoietic Stem Cell Emergence in the Zebrafish Dorsal Aorta

(2009) Robert N. Wilkinson et al.   DEVELOPMENTAL CELL

Transforming Growth Factor β Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors

(2009) Katharine H. Wrighton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood

(2008) M. Cristina Nostro et al.   Cell Stem Cell

Fli1 Acts at the Top of the Transcriptional Network Driving Blood and Endothelial Development

(2008) Feng Liu et al.   CURRENT BIOLOGY

TGF-β signaling is required for multiple processes during Xenopus tail regeneration

(2008) Diana M. Ho et al.   DEVELOPMENTAL BIOLOGY

Bmp signaling is necessary and sufficient for ventrolateral endoderm specification inXenopus

(2008) Andrea Wills et al.   DEVELOPMENTAL DYNAMICS

Transforming Growth Factor  -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth

(2008) A. C. Daly et al.   MOLECULAR AND CELLULAR BIOLOGY