Intact piRNA pathway prevents L1 mobilization in male meiosis

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer

(2016) Emma C. Scott et al.   GENOME RESEARCH

A comprehensive approach to expression of L1 loci

(2016) Prescott Deininger et al.   NUCLEIC ACIDS RESEARCH

Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline

(2016) Fang Yang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes

(2015) Peng Zhang et al.   CELL RESEARCH

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing

(2015) Anastassios Vourekas et al.   GENES & DEVELOPMENT

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination

(2015) Natasha Zamudio et al.   GENES & DEVELOPMENT

piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis

(2015) Wee Siong Sho Goh et al.   GENES & DEVELOPMENT

Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites

(2015) Fiorella C. Grandi et al.   GENOME RESEARCH

The decline of human endogenous retroviruses: extinction and survival

(2015) Gkikas Magiorkinis et al.   Retrovirology

Piwi-Pathway Alteration Induces LINE-1 Transposon Derepression and Infertility Development in Cryptorchidism

(2015) Faruk Hadziselimovic et al.   Sexual Development

Optimized flow cytometry isolation of murine spermatocytes

(2014) Valeriya Gaysinskaya et al.   CYTOMETRY PART A

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis

(2014) T. Zhang et al.   DEVELOPMENT

Two waves of de novo methylation during mouse germ cell development

(2014) A. Molaro et al.   GENES & DEVELOPMENT

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells

(2014) D. Pezic et al.   GENES & DEVELOPMENT

Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline

(2014) Toshiaki Watanabe et al.   GENOME RESEARCH

The Role of Chromatin Modifications in Progression through Mouse Meiotic Prophase

(2014) James H. Crichton et al.   Journal of Genetics and Genomics

G9a co-suppresses LINE1 elements in spermatogonia

(2014) Monica Di Giacomo et al.   Epigenetics & Chromatin

Multiple Epigenetic Mechanisms and the piRNA Pathway Enforce LINE1 Silencing during Adult Spermatogenesis

(2013) Monica Di Giacomo et al.   MOLECULAR CELL

Long Interspersed Element–1 (LINE-1): Passenger or Driver in Human Neoplasms?

(2013) Nemanja Rodić et al.   PLoS Genetics

Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus

(2012) Y. Yamamoto et al.   GENOME RESEARCH

LINE-1-Derived Poly(A) Microsatellites Undergo Rapid Shortening and Create Somatic and Germline Mosaicism in Mice

(2012) Fiorella C. Grandi et al.   MOLECULAR BIOLOGY AND EVOLUTION

Epigenetic Disruption of the PIWI Pathway in Human Spermatogenic Disorders

(2012) Holger Heyn et al.   PLoS One

Human Genetic Variation, Shared and Private

(2012) F. Casals et al.   SCIENCE

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition

(2011) Lixin Dai et al.   BMC BIOCHEMISTRY

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(2011) Michael Reuter et al.   NATURE

Production of artificial piRNAs in flies and mice

(2011) F. Muerdter et al.   RNA

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

(2011) T. Watanabe et al.   SCIENCE

The NF1 Gene Contains Hotspots for L1 Endonuclease-Dependent De Novo Insertion

(2011) Katharina Wimmer et al.   PLoS Genetics

Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs

(2011) Wenfeng An et al.   Mobile DNA

Mobile Interspersed Repeats Are Major Structural Variants in the Human Genome

(2010) Cheng Ran Lisa Huang et al.   CELL

Repeat-induced gene silencing of L1 transgenes is correlated with differential promoter methylation

(2010) James M. Rosser et al.   GENE

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes

(2010) A. D. Ewing et al.   GENOME RESEARCH

Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population

(2010) A. Gu et al.   HUMAN REPRODUCTION

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway

(2010) K. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs

(2010) R. J. A. Frost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism

(2009) H. Kano et al.   GENES & DEVELOPMENT

Mobile elements create structural variation: Analysis of a complete human genome

(2009) J. Xing et al.   GENOME RESEARCH

Mouse Maelstrom, a Component of Nuage, Is Essential for Spermatogenesis and Transposon Repression in Meiosis

(2008) Sarah F.C. Soper et al.   DEVELOPMENTAL CELL

L1 mobile element expression causes multiple types of toxicity

(2008) Nicholas A. Wallace et al.   GENE

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Conditional activation of a single-copy L1 transgene in mice by Cre

(2008) Wenfeng An et al.   GENESIS

A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice

(2008) Alexei A. Aravin et al.   MOLECULAR CELL