Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 6, Pages 1389-1394
Publisher
Proceedings of the National Academy of Sciences
Online
2017-01-24
DOI
10.1073/pnas.1620963114
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pharmacological Inhibition of BACE1 Impairs Synaptic Plasticity and Cognitive Functions
- (2015) Severin Filser et al. BIOLOGICAL PSYCHIATRY
- η-Secretase processing of APP inhibits neuronal activity in the hippocampus
- (2015) Michael Willem et al. NATURE
- Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids
- (2015) Waleska K. Martins et al. Scientific Reports
- Secreted Amyloid β-Proteins in a Cell Culture Model Include N-Terminally Extended Peptides That Impair Synaptic Plasticity
- (2014) Alfred T. Welzel et al. BIOCHEMISTRY
- Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein
- (2014) Janice A. Maloney et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amine-Containing Molecules and the Induction of an Expanded Lysosomal Volume Phenotype: A Structure–Activity Relationship Study
- (2014) Randall Logan et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Targeting the β secretase BACE1 for Alzheimer's disease therapy
- (2014) Riqiang Yan et al. LANCET NEUROLOGY
- Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering
- (2014) Dan Fu et al. Nature Chemistry
- Evaluating the Roles of Autophagy and Lysosomal Trafficking Defects in Intracellular Distribution-Based Drug-Drug Interactions Involving Lysosomes
- (2013) Randall Logan et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Familial Alzheimer’s Disease Mutations Differentially Alter Amyloid β-Protein Oligomerization
- (2012) Megan Murray Gessel et al. ACS Chemical Neuroscience
- The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species
- (2012) Jessica Bien et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- A small-molecule enhancer of autophagy decreases levels of Aβ and APP-CTF via Atg5-dependent autophagy pathway
- (2011) Yuan Tian et al. FASEB JOURNAL
- Effect of the Protonation State of the Titratable Residues on the Inhibitor Affinity to BACE-1
- (2010) José L. Domínguez et al. BIOCHEMISTRY
- Targeting lysosomes to eradicate imatinib-resistant chronic myelogenous leukemia cells
- (2010) A Puissant et al. LEUKEMIA
- Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease
- (2010) Gen He et al. NATURE
- Vacuolar ATPase-Mediated Cellular Concentration and Retention of Quinacrine: A Model for the Distribution of Lipophilic Cationic Drugs to Autophagic Vacuoles
- (2009) F. Marceau et al. DRUG METABOLISM AND DISPOSITION
- Identification of β-Secretase (BACE1) Substrates Using Quantitative Proteomics
- (2009) Matthew L. Hemming et al. PLoS One
- Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses
- (2008) Lars Bertram et al. NATURE REVIEWS NEUROSCIENCE
- A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates
- (2007) Ding Wu et al. ANALYTICAL BIOCHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now