Akt signaling is critical for memory CD8+T-cell development and tumor immune surveillance
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Title
Akt signaling is critical for memory CD8+T-cell development and tumor immune surveillance
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 7, Pages E1178-E1187
Publisher
Proceedings of the National Academy of Sciences
Online
2017-01-31
DOI
10.1073/pnas.1611299114
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Note: Only part of the references are listed.- mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
- (2015) Kristen N. Pollizzi et al. JOURNAL OF CLINICAL INVESTIGATION
- Signaling in Lymphocyte Activation
- (2015) Doreen Cantrell Cold Spring Harbor Perspectives in Biology
- Functional classification of memory CD8+ T cells by CX3CR1 expression
- (2015) Jan P. Böttcher et al. Nature Communications
- Regulation of Bim in Health and Disease
- (2015) Ronit Vogt Sionov et al. Oncotarget
- Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
- (2014) J. G. Crompton et al. CANCER RESEARCH
- FoxO3 is a negative regulator of primary CD8+ T-cell expansion but not of memory formation
- (2014) Susan Togher et al. IMMUNOLOGY AND CELL BIOLOGY
- Intravascular staining for discrimination of vascular and tissue leukocytes
- (2014) Kristin G Anderson et al. Nature Protocols
- The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection
- (2013) Myoungjoo V. Kim et al. IMMUNITY
- Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity
- (2013) Janelle A. Olson et al. IMMUNITY
- Differentiation of CD8 memory T cells depends on Foxo1
- (2013) Rodrigo Hess Michelini et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Intrinsic Role of FoxO3a in the Development of CD8+ T Cell Memory
- (2013) F. Tzelepis et al. JOURNAL OF IMMUNOLOGY
- Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation
- (2012) Rajesh R. Rao et al. IMMUNITY
- PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells
- (2012) David K. Finlay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- FOXO3 Regulates CD8 T Cell Memory by T Cell-Intrinsic Mechanisms
- (2012) Jeremy A. Sullivan et al. PLoS Pathogens
- Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism
- (2011) Andrew N. Macintyre et al. IMMUNITY
- Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo
- (2010) Vandana Kalia et al. IMMUNITY
- Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells
- (2010) Matthew E. Pipkin et al. IMMUNITY
- Distinct Roles for IL-2 and IL-15 in the Differentiation and Survival of CD8+ Effector and Memory T Cells
- (2010) D. M. Mitchell et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche
- (2010) A. Banerjee et al. JOURNAL OF IMMUNOLOGY
- Phosphoinositide (3,4,5)-Triphosphate Binding to Phosphoinositide-Dependent Kinase 1 Regulates a Protein Kinase B/Akt Signaling Threshold That Dictates T-Cell Migration, Not Proliferation
- (2009) C. Waugh et al. MOLECULAR AND CELLULAR BIOLOGY
- Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor
- (2009) Yann M Kerdiles et al. NATURE IMMUNOLOGY
- Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation
- (2009) Weiguo Cui et al. VACCINE
- Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
- (2008) Surojit Sarkar et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance
- (2008) J. R. Bayascas et al. MOLECULAR AND CELLULAR BIOLOGY
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