Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Endothelial Actin-Binding Proteins and Actin Dynamics in Leukocyte Transendothelial Migration

(2015) Michael Schnoor   JOURNAL OF IMMUNOLOGY

Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation

(2015) Melanie Greter et al.   Frontiers in Immunology

Mesenchymal Stromal Cells in Stroke: Improvement of Motor Recovery or Functional Compensation?

(2014) Johannes Boltze et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood—Brain Barrier Breakdown Involves Four Distinct Stages of Vascular Damage in Various Models of Experimental Focal Cerebral Ischemia

(2014) Martin Krueger et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mfsd2a is critical for the formation and function of the blood–brain barrier

(2014) Ayal Ben-Zvi et al.   NATURE

Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke

(2014) Jiayin Wang et al.   NEUROBIOLOGY OF DISEASE

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

Molecular dialogs between the ischemic brain and the peripheral immune system: Dualistic roles in injury and repair

(2014) Chengrui An et al.   PROGRESS IN NEUROBIOLOGY

HSP27 Protects the Blood-Brain Barrier Against Ischemia-Induced Loss of Integrity

(2013) Rehana K. Leak et al.   CNS & Neurological Disorders-Drug Targets

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

Characterization of long-term functional outcome in a murine model of mild brain ischemia

(2013) Mustafa Balkaya et al.   JOURNAL OF NEUROSCIENCE METHODS

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Blood-Brain Barrier Breakdown after Embolic Stroke in Rats Occurs without Ultrastructural Evidence for Disrupting Tight Junctions

(2013) Martin Krueger et al.   PLoS One

Adoptive regulatory T-cell therapy protects against cerebral ischemia

(2012) Peiying Li et al.   ANNALS OF NEUROLOGY

Transgenic Overexpression of Peroxiredoxin-2 Attenuates Ischemic Neuronal Injury Via Suppression of a Redox-Sensitive Pro-Death Signaling Pathway

(2012) Yu Gan et al.   ANTIOXIDANTS & REDOX SIGNALING

Phosphorylation of HSP27 by Protein Kinase D Is Essential for Mediating Neuroprotection against Ischemic Neuronal Injury

(2012) R. A. Stetler et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke

(2012) R. Khatri et al.   NEUROLOGY

Peroxisome Proliferator-Activated Receptor   Regulation of miR-15a in Ischemia-Induced Cerebral Vascular Endothelial Injury

(2010) K. J. Yin et al.   JOURNAL OF NEUROSCIENCE

Breaching multiple barriers: leukocyte motility through venular walls and the interstitium

(2010) Sussan Nourshargh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Heat shock proteins: Cellular and molecular mechanisms in the central nervous system

(2010) R. Anne Stetler et al.   PROGRESS IN NEUROBIOLOGY

Caveolae-mediated Internalization of Occludin and Claudin-5 during CCL2-induced Tight Junction Remodeling in Brain Endothelial Cells

(2009) Svetlana M. Stamatovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Regulation of Endothelial Junctional Permeability

(2008) Emily Vandenbroucke et al.   Annals of the New York Academy of Sciences

Transduced human PEP-1-heat shock protein 27 efficiently protects against brain ischemic insult

(2008) Jae J. An et al.   FEBS Journal

Hsp27 Protects against Ischemic Brain Injury via Attenuation of a Novel Stress-Response Cascade Upstream of Mitochondrial Cell Death Signaling

(2008) R. A. Stetler et al.   JOURNAL OF NEUROSCIENCE

The actin cytoskeleton in endothelial cell phenotypes

(2008) Nutan Prasain et al.   MICROVASCULAR RESEARCH

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

(2007) Marcella van Leeuwen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY