Proteasomes tether to two distinct sites at the nuclear pore complex

The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components

(2017) Silvia Salas-Pino et al.   JOURNAL OF CELL BIOLOGY

Optimized cryo-focused ion beam sample preparation aimed at in situ structural studies of membrane proteins

(2017) Miroslava Schaffer et al.   JOURNAL OF STRUCTURAL BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Structural insights into the functional cycle of the ATPase module of the 26S proteasome

(2017) Marc Wehmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting the molecular organization of the translocon-associated protein complex

(2017) Stefan Pfeffer et al.   Nature Communications

The structure of the COPI coat determined within the cell

(2017) Yury S Bykov et al.   eLife

Transcriptional regulation by complex interplay between post-translational modifications

(2016) Michael J Skelly et al.   CURRENT OPINION IN PLANT BIOLOGY

Catalytically Active Proteasomes Function Predominantly in the Cytosol

(2016) Francis Wang Dang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Situ Cryo-Electron Tomography: A Post-Reductionist Approach to Structural Biology

(2016) Shoh Asano et al.   JOURNAL OF MOLECULAR BIOLOGY

Visualizing the molecular sociology at the HeLa cell nuclear periphery

(2016) J. Mahamid et al.   SCIENCE

Nuclear pore proteins and the control of genome functions

(2015) Arkaitz Ibarra et al.   GENES & DEVELOPMENT

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

In situ structural analysis of the human nuclear pore complex

(2015) Alexander von Appen et al.   NATURE

Molecular techniques to interrogate and edit theChlamydomonasnuclear genome

(2015) Robert E. Jinkerson et al.   PLANT JOURNAL

TheChlamydomonascell cycle

(2015) Frederick R. Cross et al.   PLANT JOURNAL

In situ structural analysis of Golgi intracisternal protein arrays

(2015) Benjamin D. Engel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A molecular census of 26S proteasomes in intact neurons

(2015) S. Asano et al.   SCIENCE

Advances in Single-Particle Electron Cryomicroscopy Structure Determination applied to Sub-tomogram Averaging

(2015) Tanmay A.M. Bharat et al.   STRUCTURE

Structure and gating of the nuclear pore complex

(2015) Matthias Eibauer et al.   Nature Communications

Yeast Importin-α (Srp1) Performs Distinct Roles in the Import of Nuclear Proteins and in Targeting Proteasomes to the Nucleus

(2014) Li Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein quality control at the inner nuclear membrane

(2014) Anton Khmelinskii et al.   NATURE

Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome

(2014) P. Unverdorben et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quality control of inner nuclear membrane proteins by the Asi complex

(2014) O. Foresti et al.   SCIENCE

Autofocused 3D Classification of Cryoelectron Subtomograms

(2014) Yuxiang Chen et al.   STRUCTURE

Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome

(2014) Chan-Gi Pack et al.   Nature Communications

Proteasome dynamics

(2013) Cordula Enenkel   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold

(2013) Khanh Huy Bui et al.   CELL

PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone

(2013) Sae-Hun Park et al.   CELL

Cellular maintenance of nuclear protein homeostasis

(2013) Pamela S. Gallagher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Fast and accurate reference-free alignment of subtomograms

(2013) Yuxiang Chen et al.   JOURNAL OF STRUCTURAL BIOLOGY

The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome

(2013) Mario Niepel et al.   MOLECULAR BIOLOGY OF THE CELL

Destination: inner nuclear membrane

(2013) Santharam S. Katta et al.   TRENDS IN CELL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Focused ion beam micromachining of eukaryotic cells for cryoelectron tomography

(2012) A. Rigort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy

(2012) E. Sakata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PyTom: A python-based toolbox for localization of macromolecules in cryo-electron tomograms and subtomogram analysis

(2011) Thomas Hrabe et al.   JOURNAL OF STRUCTURAL BIOLOGY

Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8

(2011) K. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sts1 Plays a Key Role in Targeting Proteasomes to the Nucleus

(2010) Li Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

(2010) Christiane Riedinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nucleus-based Quality Control Mechanism for Cytosolic Proteins

(2010) Rupali Prasad et al.   MOLECULAR BIOLOGY OF THE CELL

Reversible cytoplasmic localization of the proteasome in quiescent yeast cells

(2008) Damien Laporte et al.   JOURNAL OF CELL BIOLOGY