Article
Neurosciences
Raquel P. Sousa Abreu, Evgeny Bondarenko, Jack L. Feldman
Summary: The study revealed that preBotC SST+ neurons, which modulate respiratory pattern but are not rhythmogenic, have different effects on breathing variables based on phase and state. Photostimulation of these neurons during inspiration in anaesthetized mice increased inspiratory duration and amplitude, with more pronounced effects at higher breathing frequencies. Also, unexpected phase- and state-dependent responses to photostimulation were observed, challenging current models of preBotC function.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Neurosciences
Hyeong-Dong Park, Timothy Piton, Oliver A. Kannape, Niall W. Duncan, Kang-Yun Lee, Timothy J. Lane, Olaf Blanke
Summary: Previous studies have shown that bodily signals from internal organs are linked to various sensory-motor functions. A recent study found that voluntary actions are associated with the breathing cycle. This study investigated whether this breathing-action coupling is limited to voluntary body movements or if it also occurs in mental actions without overt bodily movement. The results showed that both imagined and overt actions are coupled with respiration, suggesting the involvement of the breathing system in the preparatory processes of voluntary actions.
Article
Neurosciences
Adriano B. L. Tort, Maximilian Hammer, Jiaojiao Zhang, Jurij Brankack, Andreas Draguhn
Summary: The study found a strong correlation between instantaneous breathing frequency and the frequency and amplitude of theta and gamma oscillations in the brain. Changes in theta activity were found to precede and cause changes in breathing frequency, indicating control by the brain's functional state. On the other hand, changes in breathing frequency were found to cause changes in gamma frequency, suggesting influence by a peripheral reafference signal.
JOURNAL OF NEUROSCIENCE
(2021)
Editorial Material
Engineering, Environmental
Leslie J. Saunders, Frank Wania
Summary: The susceptibility of organic chemicals to elimination in air-breathing organisms can be assessed using the octanol-water partition ratio (K-OW) and the octanol-air partition ratio (K (OA)). According to regulations, chemicals with K (OW) values <10(5) and K (OA) values <10(4.85) are considered non-bioaccumulative in air breathers.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Physiology
Jun Kaminosono, Yuki Kambe, Akihide Tanimoto, Tomoyuki Kuwaki, Akira Yamashita
Summary: The optogenetic-based cardiac pacing method allows non-invasive stimulation of the cardiac muscle, producing blood flow and indirectly affecting respiration rhythm. This method is feasible in awake, freely moving mice and can be used to study the relationship between heartbeat state and animal behavior.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Neurosciences
Jesus Pujol, Laura Blanco-Hinojo, Hector Ortiz, Lluis Gallart, Luis Molto, Gerard Martinez-Vilavella, Esther Vila, Susana Pacreu, Irina Adalid, Joan Deus, Victor Perez-Sola, Juan Fernandez-Candil
Summary: Through studying the changes in breathing and brain activity during the transition from wakefulness to unconsciousness, we found that there are slight changes in breathing and these changes are associated with different brain systems involved in consciousness. The recovery of breathing is also related to the activity of deep brain structures that control basic behaviors.
Article
Psychology, Multidisciplinary
Zehava Ovadia-Blechman, Ricardo Tarrasch, Maria Velicki, Hila Chalutz Ben-Gal
Summary: This study examines the effectiveness of using slow, Device-Guided Breathing (DGB) as a self-treatment clinical tool for reducing test anxiety. The results suggest that daily practice of DGB may lead to anxiety reduction and potentially improve test performance. This research presents an alternative treatment for test anxiety that could be important, especially during the ongoing COVID-19 pandemic.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Agronomy
Nitin Sharma, Meenakshi Thakur, Pavithra Suryakumar, Purbali Mukherjee, Ali Raza, Channapatna S. Prakash, Anjali Anand
Summary: Respiration and photosynthesis in plants are negatively affected by elevated temperatures, leading to disruptions in the plant's carbon economy. This review discusses the mechanistic insight into the heat stress-induced mitochondrial dysfunction in plants, which affects dark respiration. The role of hormones in regulating retrograde signaling is highlighted, and different strategies to reduce carbon loss under high temperatures are proposed, including selecting genotypes with low respiration rates and using genome editing tools.
Article
Clinical Neurology
Maximilian Hammer, Chrysovalandis Schwale, Jurij Brankack, Andreas Draguhn, Adriano B. L. Tort
Summary: This study reveals an unexpected relationship between theta-gamma coupling and respiration in mice, showing that the strength of coupling is inversely related to breathing rate. Interestingly, breathing is found to differently influence theta-gamma coupling during phasic and tonic REM states, suggesting a more complex link between respiration and cortical network activity patterns.
Article
Clinical Neurology
Maximilian Hammer, Chrysovalandis Schwale, Jurij Brankack, Andreas Draguhn, Adriano B. L. Tort
Summary: The study reveals an unexpected but robust relation between theta-gamma coupling and respiration in mice, with the strength of coupling exhibiting an inverted V-shaped dependence on breathing rate. The findings also show that breathing differentially relates to theta-gamma coupling in different sleep states, indicating a more complex link between respiration and brain activity.
Article
Nutrition & Dietetics
Jou-Chung Chang, Sarah A. Angus, Connor J. Doherty, Benjamin P. Thompson, Leah M. Mann, Yannick Molgat-Seon, Paolo B. Dominelli
Summary: The perception of dyspnea during exercise can be altered by prior exposure to heightened dyspnea. This study found that dyspnea perception was significantly lower on the second day of exercise testing at 60%-80% of peak VO2, compared to the first day.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2023)
Letter
Engineering, Electrical & Electronic
Emanuel Gluskin
Summary: The author corrected the balance equation for the number of corona virus molecules in the lung, and derived an important inequality for the required breathing frequency. It is immediately evident that small living organisms are better able to tolerate the CV-environment.
INTERNATIONAL JOURNAL OF CIRCUIT THEORY AND APPLICATIONS
(2021)
Article
Critical Care Medicine
Annia F. Schreiber, Michele Bertoni, Benjamin Coiffard, Samira Fard, Jenna Wong, W. Darlene Reid, Laurent J. Brochard, Simone Piva, Ewan C. Goligher
Summary: Ultrasound assessment of abdominal muscle thickening is feasible and moderately reproducible in mechanically ventilated patients. Reduced abdominal muscle thickening during cough in patients who passed a spontaneous breathing trial is associated with an increased risk of liberation failure.
Article
Physiology
Michele L. Singer, Ethan S. Benevides, Sabhya Rana, Michael D. Sunshine, Robert C. Martinez, Brian E. Barral, Barry J. Byrne, David D. Fuller
Summary: Inadequate tongue muscle activation leads to dysarthria, dysphagia, and obstructive sleep apnea. Injecting an adeno-associated virus encoding channelrhodopsin-2 (ChR2) into the tongue enables light-induced activation of tongue motor units. This study demonstrates the potential of intralingual AAV9-ChR2 delivery for lingual therapeutics.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2023)
Review
Physiology
Eric Harbour, Thomas Stoeggl, Hermann Schwameder, Thomas Finkenzeller
Summary: Running is a popular sporting hobby, but a significant percentage of runners may experience exercise-induced dyspnoea. While deep breathing techniques have proven benefits at rest, it is unclear if they can improve respiratory limitations or performance during exercise.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
R. T. Gardner, L. Wang, B. T. Lang, J. M. Cregg, C. L. Dunbar, W. R. Woodward, J. Silver, C. M. Ripplinger, B. A. Habecker
NATURE COMMUNICATIONS
(2015)
Article
Neurosciences
Jon P. Niemi, Alicia DeFrancesco-Lisowitz, Jared M. Cregg, Madeline Howarth, Richard E. Zigmond
EXPERIMENTAL NEUROLOGY
(2016)
Article
Cell Biology
Jared M. Cregg, Kevin A. Chu, Lydia E. Hager, Rachel S. J. Maggard, Daimen R. Stoltz, Michaela Edmond, Warren J. Alilain, Polyxeni Philippidou, Lynn T. Landmesser, Jerry Silver
Article
Engineering, Biomedical
Han Bing Wang, Michael E. Mullins, Jared M. Cregg, Connor W. McCarthy, Ryan J. Gilbert
ACTA BIOMATERIALIA
(2010)
Article
Engineering, Biomedical
Andres Hurtado, Jared M. Cregg, Han B. Wang, Dane F. Wendell, Martin Oudega, Ryan J. Gilbert, John W. McDonald
Review
Neurosciences
Jared M. Cregg, Marc A. DePaul, Angela R. Filous, Bradley T. Lang, Amanda Tran, Jerry Silver
EXPERIMENTAL NEUROLOGY
(2014)
Editorial Material
Neurosciences
Brett J. Hilton, Bradley T. Lang, Jared M. Cregg
JOURNAL OF NEUROSCIENCE
(2012)
Article
Multidisciplinary Sciences
Bradley T. Lang, Jared M. Cregg, Marc A. DePaul, Amanda P. Tran, Kui Xu, Scott M. Dyck, Kathryn M. Madalena, Benjamin P. Brown, Yi-Lan Weng, Shuxin Li, Soheila Karimi-Abdolrezaee, Sarah A. Busch, Yingjie Shen, Jerry Silver
Article
Cell & Tissue Engineering
Jared M. Cregg, Sherri L. Wiseman, Nicole M. Pietrzak-Goetze, Martyn R. Smith, David B. Jaroch, Daniel C. Clupper, Ryan J. Gilbert
TISSUE ENGINEERING PART C-METHODS
(2010)
Article
Multidisciplinary Sciences
Angela M. Lager, Olivia G. Corradin, Jared M. Cregg, Matthew S. Elitt, H. Elizabeth Shick, Benjamin L. L. Clayton, Kevin C. Allan, Hannah E. Olsen, Mayur Madhavan, Paul J. Tesar
NATURE COMMUNICATIONS
(2018)
Article
Biology
Alicia N. Vagnozzi, Kiran Garg, Carola Dewitz, Matthew T. Moore, Jared M. Cregg, Lucie Jeannotte, Niccolo Zampieri, Lynn T. Landmesser, Polyxeni Philippidou
Article
Neurosciences
Jared M. Cregg, Roberto Leiras, Alexia Montalant, Paulina Wanken, Ian R. Wickersham, Ole Kiehn
NATURE NEUROSCIENCE
(2020)
Review
Neurosciences
Roberto Leiras, Jared M. Cregg, Ole Kiehn
Summary: This review examines recent advances in understanding the brainstem circuits involved in controlling locomotion. The study highlights the importance of delineated command circuits and the need to establish functional connections between these circuits and other brain areas. The unresolved issues regarding the integrated function of locomotor control are also discussed.
ANNUAL REVIEW OF NEUROSCIENCE
(2022)
Editorial Material
Neurosciences
Jared M. Cregg, Jasmine L. Mirdamadi, Catia Fortunato, Elizaveta V. Okorokova, Clara Kuper, Rashida Nayeem, Andrew J. Byun, Chen Avraham, Antimo Buonocore, Taniel S. Winner, Robyn L. Mildren
JOURNAL OF NEUROPHYSIOLOGY
(2023)