Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase

Gain-of-function mutations ofPtpn11(Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies

(2016) Xia Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms

(2014) Shuang Zhang et al.   CELL RESEARCH

H2B Ubiquitylation Promotes RNA Pol II Processivity via PAF1 and pTEFb

(2014) Lipeng Wu et al.   MOLECULAR CELL

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

(2014) Bo Li et al.   NATURE

The Epidermal Growth Factor Receptor Critically Regulates Endometrial Function during Early Pregnancy

(2014) Michael J. Large et al.   PLoS Genetics

YAP and TAZ, Hippo Signaling Targets, Act as a Rheostat for Nuclear SHP2 Function

(2013) Ryouhei Tsutsumi et al.   DEVELOPMENTAL CELL

A Positive Feedback Loop Involving Gcm1 and Fzd5 Directs Chorionic Branching Morphogenesis in the Placenta

(2013) Jinhua Lu et al.   PLOS BIOLOGY

Wnt6 Is Essential for Stromal Cell Proliferation During Decidualization in Mice1

(2012) Qiang Wang et al.   BIOLOGY OF REPRODUCTION

Nuclear Receptor Coactivator-6 Attenuates Uterine Estrogen Sensitivity to Permit Embryo Implantation

(2012) Jun Kawagoe et al.   DEVELOPMENTAL CELL

ERα Phosphorylation at Y537 by Src Triggers E6-AP-ERα Binding, ERα Ubiquitylation, Promoter Occupancy, and Target Gene Expression

(2012) Jun Sun et al.   MOLECULAR ENDOCRINOLOGY

SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver

(2011) Atsushi Takahashi et al.   MOLECULAR CELL

Nuclear Protein Tyrosine Phosphatase Shp-2 Is One Important Negative Regulator of Nuclear Export of Telomerase Reverse Transcriptase

(2008) Sascha Jakob et al.   JOURNAL OF BIOLOGICAL CHEMISTRY