Review
Medicine, General & Internal
Shuangtao Xing, Shijie Feng, Dan Zeng
Summary: This study compared the effects of different types of exercise on pulmonary function in adult patients with asthma through Network Meta-analysis. The results showed that breathing training, aerobic training, relaxation training, yoga training, and breathing combined with aerobic training significantly improved Forced Expiratory Volume in the first second (FEV1) levels; aerobic training, breathing training, yoga training, and breathing combined with aerobic training improved Forced Vital Capacity (FVC) levels; breathing training, aerobic training, relaxation training, yoga training, and breathing combined with aerobic training improved Peak Expiratory Flow (PEF) levels; breathing training, aerobic training, and yoga training improved Forced Expiratory Volume in the first second/Forced Vital Capacity (FEV1/FVC) levels.
ANNALS OF MEDICINE
(2023)
Article
Endocrinology & Metabolism
Jagdish Prasad Goyal, Prawin Kumar, Chirag Thakur, Daisy Khera, Kuldeep Singh, Praveen Sharma
Summary: This study found that insulin resistance may be related to decreased lung function in asthmatic children, but after adjusting for age, gender, and body mass index, the association was not significant.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
(2022)
Article
Health Care Sciences & Services
Tzu-Ning Wen, Hsueh-Chun Lin, Kuo-Wei Yeh, Jing-Long Huang, Li-Chi Chiang
Summary: A web-based self-health management system, eAsthmaCare, was developed as an intervention for asthmatic children. The study found that eAsthmaCare intervention can improve childhood asthma symptoms, particularly in relation to sleeping condition and cough symptoms. However, there was no statistically significant improvement in lung function.
JOURNAL OF MEDICAL SYSTEMS
(2022)
Article
Environmental Sciences
Chang Huang, Jian Lei, Jun Wang, Yue Niu, Yixiang Zhu, Yixuan Jiang, Xiaowei Xue, Ya Gao, Haidong Kan, Renjie Chen
Summary: Evidence on the comparative effects of fine particulate matter (PM2.5) and coarse particulate matter (PM10-2.5) on the lung function of asthmatic children remained limited and inconsistent. This study found that short-term exposure to both PM2.5 and PM10-2.5 could decrease the daily lung function of asthmatic children, and the impact of PM10-2.5 was more hazardous than PM2.5.
ATMOSPHERIC ENVIRONMENT
(2023)
Review
Pediatrics
Zenghui Jing, Xingzhi Wang, Panpan Zhang, Jinli Huang, Yuanyuan Jia, Juan Zhang, Huajie Wu, Xin Sun
Summary: In this meta-analysis, we updated the effects of physical activity (PA) in asthmatic children over the past 10 years. It was found that PA significantly improved lung function and quality of life in asthmatic children.
FRONTIERS IN PEDIATRICS
(2023)
Article
Geriatrics & Gerontology
Zhigang Hu, Yufeng Tian, Xinyu Song, Fanjun Zeng, Ailan Yang
Summary: This study found that the prevalence of sarcopenia is higher in asthmatics compared to those without asthma. Asthmatics with sarcopenia have a higher risk of severe shortness of breath, airway obstruction, and reduced lung function.
Article
Allergy
Takashi Sakama, Mami Ichinose, Takeru Obara, Mayuko Shibata, Takanori Kagawa, Hiromitsu Takakura, Kota Hirai, Hiroyuki Furuya, Masahiko Kato, Hiroyuki Mochizuki
Summary: This study found a correlation between wheeze and decreased lung function in children with asthma. Using lung sound analysis can provide accurate information about the condition of the airways in asthmatic children.
ALLERGOLOGY INTERNATIONAL
(2023)
Article
Pediatrics
Annalisa Cogo, Michele Piazza, Silvia Costella, Massimiliano Appodia, Raffaele Aralla, Stefania Zanconato, Silvia Carraro, Giorgio Piacentini
Summary: This study aims to investigate the changes in respiratory function during the first two weeks of stay in a mountain environment for asthmatic children. The results showed improvement in respiratory indices as early as after 24 hours of stay, persisting in the following week.
PEDIATRIC PULMONOLOGY
(2022)
Article
Multidisciplinary Sciences
Nicolas Todd, Mathias Lerch
Summary: The relationship between breastfeeding and postpartum amenorrhea has weakened globally over time, with factors such as Human Development Index, urbanization, access to electricity, water, and education influencing the association. Low parity and exclusive breastfeeding in Asia also play a role in maintaining postpartum amenorrhea.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Medicine, General & Internal
Wei Jin, Zichong Zhao, Dongping Zhou
Summary: This study investigated the effects of the combination of montelukast sodium and budesonide aerosol on airway function and T lymphocytes in asthmatic children. The findings showed that the combination treatment effectively improved airway function, regulated T lymphocyte levels, and reduced inflammatory reactions.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2022)
Article
Respiratory System
Liangqin Yi, Yan Zhao, Ziyao Guo, Qinyuan Li, Guangli Zhang, Xiaoyin Tian, Ximing Xu, Zhengxiu Luo
Summary: This study aimed to investigate the role of small airway function parameters in evaluating airway dysfunction, airflow limitation, and airway hyperresponsiveness in preschool asthmatic children. The results showed strong correlations between small airway function parameters and large airway function parameters, as well as a close relationship between small airway dysfunction and severe airflow obstruction and airway hyperresponsiveness. Therefore, the utilization of small airway function parameters in the management of preschool asthma is highly important.
BMC PULMONARY MEDICINE
(2023)
Article
Immunology
Chihiro Tomiaki, Kosuke Miyauchi, Sewon Ki, Yoshie Suzuki, Narumi Suzuki, Hiroshi Morimoto, Yohei Mukoyama, Masato Kubo
Summary: FK506 effectively suppresses airway inflammation by inhibiting ILC2 activation and T1/ST2(+) CD4 T cell accumulation.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
Linchen He, Christina Norris, Xiaoxing Cui, Zhen Li, Karoline K. Barkjohn, Yanbo Teng, Lin Fang, Lili Lin, Qian Wang, Xiaojian Zhou, Jianguo Hong, Feng Li, Yinping Zhang, James J. Schauer, Marilyn Black, Michael H. Bergin, Junfeng (Jim) Zhang
Summary: The study found that oxidative stress and inflammation are important pathophysiological mechanisms underlying the effects of air pollution in children with asthma. Melatonin can suppress oxidative stress and inflammation, leading to improved airway inflammation and lung elasticity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Nutrition & Dietetics
Anamaria Cozma-Petrut, Lorena Filip, Roxana Banc, Oana Mirza, Laura Gavrilas, Daniela Ciobarca, Ioana Badiu-Tisa, Simona Codruta Heghes, Cristian Olimpiu Popa, Doina Miere
Summary: This study investigated breastfeeding practices in northwestern Romania and found that almost all mothers breastfed their children at least once, with an exclusive breastfeeding rate of 46.7%. Improving rates in all breastfeeding practices suggest the need for continued efforts to develop effective national policies and programs to promote breastfeeding in Romania.
Article
Nutrition & Dietetics
Ziming Yang, Yingfang Ding, Shuyao Song, Yaoyun Zhang, Aolin Li, Mintao Su, Yajun Xu
Summary: The objective of this study was to investigate the factors affecting the duration of continuous breastfeeding of infants within 2 years of age in China and explore intervention strategies to promote breastfeeding duration. A self-made electronic questionnaire was used to collect data on breastfeeding duration and influencing factors from individual, family, and social support levels. The findings showed that breastfeeding duration in China is generally short, with a low proportion of mothers breastfeeding until the recommended age of 2 years and above. Multiple factors at different levels influence breastfeeding duration. It is suggested to improve the situation through health education, system security improvement, and enhanced social support.
Article
Allergy
Kyung Won Kim, Dong Yun Kim, Dankyu Yoon, Ka-Kyung Kim, Haerin Jang, Nathan Schoettler, Eun Gyul Kim, Mi Na Kim, Jung Yeon Hong, Jeom-Kyu Lee, Sangwoo Kim, Carole Ober, Heon Yung Gee, Myung Hyun Sohn
Summary: This study identified a new susceptibility gene, TNFSF15, and replicated associations at the 17q12-21 locus for childhood-onset asthma in Korean children with persistent asthma. The novel association may be mediated by reduced expression of serum TNFSF15 and loss of suppression of angiogenesis.
Article
Biochemistry & Molecular Biology
Mi Na Kim, Jung Yeon Hong, Eun Gyul Kim, Jae Woo Lee, Soo Yeon Lee, Kyung Won Kim, Hyo Sup Shim, Chun Geun Lee, Jack A. Elias, Yong Ju Lee, Myung Hyun Sohn
Summary: ALCAM plays a protective role in the development of pulmonary fibrosis by inhibiting epithelial cell apoptosis through the PI3K-Akt signaling pathway. This finding may contribute to the development of therapeutic strategies for IPF patients.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jae Woo Lee, Mi Na Kim, Eun Gyul Kim, Ji Su Leem, Seung Min Baek, Min Jung Kim, Kyung Won Kim, Myung Hyun Sohn
Summary: Viral respiratory infections can cause lung diseases with inflammation. CHI3L1 protein may be involved in regulating inflammatory responses through the MAPK pathways in airway epithelial cells following viral infections.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Medicine, General & Internal
Ji Young Lee, Seung Hwan Baek, Jong Gyun Ahn, Seo Hee Yoon, Moon Kyu Kim, Soo Yeon Kim, Kyung Won Kim, Myung Hyun Sohn, Ji-Man Kang
Summary: This study aimed to examine the delay in antiviral initiation in RAT false-negative children with influenza virus infection, and found that delayed antiviral treatment may be associated with severe influenza infection and the need for mechanical ventilation. Additionally, the medical cost varied among different scenarios.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Article
Allergy
Kun-Baek Song, Min Jee Park, Eom Ji Choi, Sungsu Jung, Jisun Yoon, Hyun-Ju Cho, Bong-Seong Kim, Kangmo Ahn, Kyung Won Kim, Youn Ho Shin, Dong In Suh, Soo-Jong Hong, So-Yeon Lee
Summary: The level of pollen in Korea has increased in recent decades. This study investigated the prevalence and characteristics of oral allergy syndrome (OAS) in children aged 6-10 years from a general-population-based birth cohort. The study found that food allergy and food sensitization in early childhood were associated with OAS in schoolchildren with allergic rhinitis (AR).
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Jeong Eun Shin, Haerin Jang, Jung Ho Han, Joonsik Park, Soo Yeon Kim, Yoon Hee Kim, Ho Seon Eun, Soon Min Lee, Kook In Park, Myung Hyun Sohn, Min Soo Park, Kyung Won Kim
Summary: Bronchopulmonary dysplasia (BPD) may have an impact on childhood lower respiratory illness (LRI) and asthma after the neonatal period. The study found that BPD is associated with higher rates of LRI readmission and asthma prevalence in children with respiratory distress syndrome (RDS).
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Yura Kim, Jae Hwa Jung, Ga Eun Kim, Mireu Park, Myeongjee Lee, Soo Yeon Kim, Min Jung Kim, Yoon Hee Kim, Kyung Won Kim, Myung Hyun Sohn
Summary: Hypoxemia and multiple organ dysfunction contribute to mortality in patients with pediatric acute respiratory distress syndrome (PARDS). This study found that P50 levels, a measure of hemoglobin-oxygen affinity, increased with PARDS severity and were positively associated with extrapulmonary organ dysfunction and mortality risk.
SCIENTIFIC REPORTS
(2022)
Letter
Pediatrics
You Min Kang, Ga Eun Kim, Mireu Park, Jong Deok Kim, Min Jung Kim, Yoon Hee Kim, Kyung Won Kim, Myung Hyun Sohn, Soo Yeon Kim
CLINICAL AND EXPERIMENTAL PEDIATRICS
(2023)
Article
Multidisciplinary Sciences
Hye Rin Kim, Mi Na Kim, Eun Gyul Kim, Ji Su Leem, Seung Min Baek, Yu Jin Lee, Kyung Won Kim, Min-Jong Kang, Tae Won Song, Myung Hyun Sohn
Summary: This study found that a genetic deficit in NLRX1 can suppress hyperoxia-induced apoptosis, suggesting that NLRX1 acts as a pivotal regulator of hyperoxic acute lung injury (HALI).
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Chang Hoon Han, Mireu Park, Hamin Kim, Yun Young Roh, Soo Yeon Kim, Jong Deok Kim, Min Jung Kim, Yong Ju Lee, Kyung Won Kim, Yoon Hee Kim
Summary: The RALE score quantifies lung edema objectively and serves as a valuable prognostic marker for adult acute respiratory distress syndrome (ARDS). This study evaluated the validity of the RALE score in children with ARDS and found it to be reliable and correlated with other ARDS severity indices. The score was a good predictor of ARDS-specific mortality and provided information for determining the timing of aggressive therapy and managing fluid balance.
YONSEI MEDICAL JOURNAL
(2023)
Article
Allergy
Kyunguk Jeong, Jihyun Kim, Hyoung Yoon Chang, Tae Won Song, Jeong Hee Kim, Meeyong Shin, Taek Ki Min, Sun Hee Choi, Yong Ju Lee, Kyung Won Kim, Woo Kyung Kim, You Hoon Jeon, Hye Yung Yum, Kangmo Ahn, Sooyoung Lee, Young Min Ahn, Gwang Cheon Jang
Summary: This study investigated the psychological burden on mothers of children with recent anaphylaxis. It found that 56.9% of mothers had post-traumatic stress symptoms (PTSS), 18.6% had anxiety and 33.0% had depression. A history of asthma and central nervous symptoms were associated with PTSS, while being 2 years or older and anaphylaxis caused by eggs, milk, or wheat increased the risk of severe PTSS.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2022)
Article
Allergy
So-Yeon Lee, Sangrok Kim, Mi Jin Kang, Kun-Baek Song, Eom Ji Choi, Sungsu Jung, Ji-Sun Yoon, Dong In Suh, Youn Ho Shin, Kyung Won Kim, Kangmo Ahn, Soo -Jong Hong
Summary: This study investigated the relationship between the phenotype of AD in early childhood and childhood asthma and found that the presence of FA in various phenotypes of AD may be associated with gut Wnt signaling and the later development of asthma.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2022)
Article
Allergy
Eun Gyul Kim, Ji Su Leem, Seung Min Baek, Hye Rin Kim, Kyung Won Kim, Mi Na Kim, Myung Hyun Sohn
Summary: This study investigated the role of IL-18R alpha in food allergy induction and development. The results showed that IL-18R alpha regulates allergic reactions and immune responses by regulating T cell responses in food allergies. IL-18R alpha is also involved in the STAT/SOCS signaling pathways. Targeting IL-18R alpha signaling might be a novel therapeutic strategy for food allergy.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2022)
