4.7 Article

Spin fluorescence silencing enables an efficient thermally driven self-reporting polymer release system

Journal

POLYMER CHEMISTRY
Volume 8, Issue 40, Pages 6199-6203

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7py01437f

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Funding

  1. German Research Council (DFG)
  2. Karlsruhe Institute of Technology (KIT) in the context of the Helmholtz BioInterfaces in Technology and Medicine (BIFTM)
  3. Science and Technology of Nanosystems (STN)
  4. Queensland University of Technology (QUT)
  5. Australian Research Council (ARC)

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We pioneer a self-reporting profluorescent release system driven by the thermo-reversible dynamic covalent ligation of chromophores to a lateral polymer chain, whose fluorescence is silenced by unpaired spins of nitroxide moieties prior to release. The introduced technology platform holds significant potential for imaging substrate release events.

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