Differential expression of islet glutaredoxin 1 and 5 with high reactive oxygen species production in a mouse model of diabesity

Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes

(2016) Kelei Dong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats

(2016) Ana Cláudia Munhoz et al.   PLoS One

Glucose-induced glutathione reduction in mitochondria is involved in the first phase of pancreatic β-cell insulin secretion

(2015) Xiaojing Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells

(2014) Hilton K. Takahashi et al.   BIOCHEMICAL JOURNAL

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

(2013) Eva-Maria Hanschmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation

(2013) Petra Haunhorst et al.   MOLECULAR BIOLOGY OF THE CELL

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines

(2012) Jakob Bondo Hansen et al.   Cell Metabolism

NADPH Oxidase NOX2 Defines a New Antagonistic Role for Reactive Oxygen Species and cAMP/PKA in the Regulation of Insulin Secretion

(2012) N. Li et al.   DIABETES

Dietary iron restriction or iron chelation protects from diabetes and loss of β-cell function in the obese (ob/ob lep−/−) mouse

(2010) Robert C. Cooksey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Characterization of the human monothiol glutaredoxin 3 (PICOT) as iron–sulfur protein

(2010) Petra Haunhorst et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure

(2010) O. Kluth et al.   DIABETOLOGIA

Functional recovery of diabetic mouse hearts by glutaredoxin-1 gene therapy: role of Akt-FoxO-signaling network

(2010) I Lekli et al.   GENE THERAPY

Postischemic Deactivation of Cardiac Aldose Reductase

(2010) Karin Wetzelberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantification of pancreatic islet distribution in situ in mice

(2009) German Kilimnik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glutaredoxin-1 Mediates NADPH-Dependent Stimulation of Calcium-Dependent Insulin Secretion

(2009) Thomas M. Reinbothe et al.   MOLECULAR ENDOCRINOLOGY

PICOT, protein kinase C θ-interacting protein, is a novel regulator of FcεRI-mediated mast cell activation

(2008) Natsumi Kato et al.   CELLULAR IMMUNOLOGY

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

(2008) C. Leloup et al.   DIABETES

Impaired Anaplerosis and Insulin Secretion in Insulinoma Cells Caused by Small Interfering RNA-mediated Suppression of Pyruvate Carboxylase

(2008) Noaman M. Hasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY