Development of a Novel Vaccine Containing Binary Toxin for the Prevention of Clostridium difficile Disease with Enhanced Efficacy against NAP1 Strains

Development and Optimization of a High-Throughput Assay To Measure Neutralizing Antibodies against Clostridium difficile Binary Toxin

(2014) Jinfu Xie et al.   Clinical and Vaccine Immunology

Guidelines for Diagnosis, Treatment and Prevention of Clostridium difficile Infections

(2013) Christina M Surawicz et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Development and Optimization of a Novel Assay To Measure Neutralizing Antibodies against Clostridium difficile Toxins

(2013) Jinfu Xie et al.   Clinical and Vaccine Immunology

Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain

(2013) Sarah A. Kuehne et al.   JOURNAL OF INFECTIOUS DISEASES

Systemic antibody responses induced by a two-component Clostridium difficile toxoid vaccine protect against C. difficile-associated disease in hamsters

(2013) N. G. Anosova et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile

(2013) R. G. K. Donald et al.   MICROBIOLOGY-SGM

Clostridium difficile Ribotype Does Not Predict Severe Infection

(2012) Seth T. Walk et al.   CLINICAL INFECTIOUS DISEASES

Epidemiology, diagnosis and treatment ofClostridium difficileinfection

(2012) Matteo Bassetti et al.   Expert Review of Anti-Infective Therapy

A Chimeric Toxin Vaccine Protects against Primary and Recurrent Clostridium difficile Infection

(2012) Haiying Wang et al.   INFECTION AND IMMUNITY

Predicting Recurrence of C. difficile Colitis Using Bacterial Virulence Factors: Binary Toxin Is the Key

(2012) David B. Stewart et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Clostridium difficile: Development of a novel candidate vaccine

(2012) Ginamarie Foglia et al.   VACCINE

Lack of association of tcdC type and binary toxin status with disease severity and outcome in toxigenic Clostridium difficile

(2011) Simon D. Goldenberg et al.   JOURNAL OF INFECTION

Predictors of Death afterClostridium difficileInfection: A Report on 128 Strain‐Typed Cases from a Teaching Hospital in the United Kingdom

(2010) Vhairi Wilson et al.   CLINICAL INFECTIOUS DISEASES

Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)

(2010) Stuart H. Cohen et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Health Care–AssociatedClostridium difficileInfection in Canada: Patient Age and Infecting Strain Type Are Highly Predictive of Severe Outcome and Mortality

(2009) Mark Miller et al.   CLINICAL INFECTIOUS DISEASES

Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa fromClostridium difficile

(2009) Amit Sundriyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing inClostridium difficileToxin A

(2009) Rory N. Pruitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

(2009) Carsten Schwan et al.   PLoS Pathogens

Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores

(2008) J. A. Sorg et al.   JOURNAL OF BACTERIOLOGY

Autocatalytic Processing ofClostridium difficileToxin B

(2008) Martina Egerer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1

(2008) T. Akerlund et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells

(2008) R. Gerhard et al.   JOURNAL OF MEDICAL MICROBIOLOGY