Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

Diabetes Susceptibility GenesPdx1andClec16aFunction in a Pathway Regulating Mitophagy in β-Cells

(2015) Scott A. Soleimanpour et al.   DIABETES

The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

(2014) Scott A. Soleimanpour et al.   CELL

Human IAPP–induced pancreatic β cell toxicity and its regulation by autophagy

(2014) Nayumi Shigihara et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

(2014) Jacqueline F. Rivera et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic  -cell function in diabetes

(2014) A. Hoshino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Voltage-gated Potassium Channel Kv2.2 Expression by Pyruvate-Isocitrate Cycling Regulates Glucose-stimulated Insulin Secretion

(2013) Mette V. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic  -cells

(2013) Y. H. C. Yang et al.   JOURNAL OF CELL SCIENCE

The role of aging upon β cell turnover

(2013) Jake A. Kushner   JOURNAL OF CLINICAL INVESTIGATION

DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research

(2013) Catherine Y. Seiler et al.   NUCLEIC ACIDS RESEARCH

Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death

(2012) Alberto Bartolome et al.   Autophagy

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

(2012) Samuel B. Stephens et al.   Cell Metabolism

Stimulation of Autophagy Improves Endoplasmic Reticulum Stress-Induced Diabetes

(2012) E. Bachar-Wikstrom et al.   DIABETES

Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells

(2012) Wenying Quan et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets

(2012) Luisa Martino et al.   PLoS One

Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice

(2011) W. Quan et al.   DIABETOLOGIA

Contamination with E1A-Positive Wild-Type Adenovirus Accounts for Species-Specific Stimulation of Islet Cell Proliferation by CCK: A Cautionary Note

(2010) Jeremy A. Lavine et al.   MOLECULAR ENDOCRINOLOGY

Age-Dependent Decline in  -Cell Proliferation Restricts the Capacity of  -Cell Regeneration in Mice

(2009) S.-I. Tschen et al.   DIABETES

Adaptive  -Cell Proliferation Is Severely Restricted With Advanced Age

(2009) M. M. Rankin et al.   DIABETES

Autophagy in human type 2 diabetes pancreatic beta cells

(2009) M. Masini et al.   DIABETOLOGIA

Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

(2008) Hye Seung Jung et al.   Cell Metabolism

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism

Stimulation of Human and Rat Islet  -Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

(2008) J. C. Schisler et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY