Mechanism for generation of left isomerism in Ccdc40 mutant embryos

Basal body proteins regulate Notch signaling through endosomal trafficking

(2014) C. C. Leitch et al.   JOURNAL OF CELL SCIENCE

Wnt signaling regulates left–right axis formation in the node of mouse embryos

(2013) Keiko Kitajima et al.   DEVELOPMENTAL BIOLOGY

Defective Nodal and Cerl2 expression in the Arl13bhnn mutant node underlie its heterotaxia

(2012) Christine E. Larkins et al.   DEVELOPMENTAL BIOLOGY

Mutations inCCDC39andCCDC40are the Major Cause of Primary Ciliary Dyskinesia with Axonemal Disorganization and Absent Inner Dynein Arms

(2012) Dinu Antony et al.   HUMAN MUTATION

Delineation ofCCDC39/CCDC40mutation spectrum and associated phenotypes in primary ciliary dyskinesia

(2012) Sylvain Blanchon et al.   JOURNAL OF MEDICAL GENETICS

Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2

(2012) S. Yoshiba et al.   SCIENCE

Two rotating cilia in the node cavity are sufficient to break left–right symmetry in the mouse embryo

(2012) Kyosuke Shinohara et al.   Nature Communications

Fluid flow and interlinked feedback loops establish left–right asymmetric decay of Cerl2 mRNA

(2012) Tetsuya Nakamura et al.   Nature Communications

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

Left–right asymmetry in the level of active Nodal protein produced in the node is translated into left–right asymmetry in the lateral plate of mouse embryos

(2011) Aiko Kawasumi et al.   DEVELOPMENTAL BIOLOGY

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Notch signalling regulates left-right asymmetry through ciliary length control

(2010) S. S. Lopes et al.   DEVELOPMENT

The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

(2010) Anita Becker-Heck et al.   NATURE GENETICS

CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

(2010) Anne-Christine Merveille et al.   NATURE GENETICS

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Disorders of left-right asymmetry: Heterotaxy and situs inversus

(2009) Mardi J. Sutherland et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos

(2009) S. Oki et al.   DEVELOPMENT

Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants

(2007) Jessica Sullivan-Brown et al.   DEVELOPMENTAL BIOLOGY