Direct versus indirect actions of ghrelin on hypothalamic NPY neurons

Lipopolysaccharide (LPS) and tumor necrosis factor alpha (TNFα) blunt the response of Neuropeptide Y/Agouti-related peptide (NPY/AgRP) glucose inhibited (GI) neurons to decreased glucose

(2016) Lihong Hao et al.   BRAIN RESEARCH

CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting

(2016) Yael Kuperman et al.   Cell Metabolism

Rho kinase activity governs arteriolar myogenic depolarization

(2016) Yao Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia

(2016) David B. Kurland et al.   Journal of Neuroinflammation

Hypothalamic arcuate nucleus tyrosine hydroxylase neurons play orexigenic role in energy homeostasis

(2016) Xiaobing Zhang et al.   NATURE NEUROSCIENCE

Glibenclamide for the Treatment of Ischemic and Hemorrhagic Stroke

(2015) Nicholas Caffes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis

(2015) Tapas K. Makar et al.   Journal of Neuroinflammation

KATPchannels in the nodose ganglia mediate the orexigenic actions of ghrelin

(2015) Gintautas Grabauskas et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ghrelin

(2015) T.D. Müller et al.   Molecular Metabolism

The TRPM4 channel inhibitor 9-phenanthrol

(2014) R Guinamard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of A-Type Potassium Current by the Peptide Toxin SNX-482

(2014) T. Kimm et al.   JOURNAL OF NEUROSCIENCE

Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans

(2014) Arjun Khanna et al.   Neurosurgical Focus

Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects

(2014) Ninda Syam et al.   Frontiers in Cellular Neuroscience

Hypothalamic Inflammation: Marker or Mechanism of Obesity Pathogenesis?

(2013) Joshua P. Thaler et al.   DIABETES

ComplexN-Glycosylation Stabilizes Surface Expression of Transient Receptor Potential Melastatin 4b Protein

(2013) Seung Kyoon Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glibenclamide in Cerebral Ischemia and Stroke

(2013) J. Marc Simard et al.   Neurocritical Care

Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells

(2013) Mohamed-Yassine Amarouch et al.   NEUROSCIENCE LETTERS

Inhibition of the Sur1-Trpm4 Channel Reduces Neuroinflammation and Cognitive Impairment in Subarachnoid Hemorrhage

(2013) Cigdem Tosun et al.   STROKE

Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin

(2013) Qian Wang et al.   Molecular Metabolism

The Sulfonylurea Receptor 1 (Sur1)-Transient Receptor Potential Melastatin 4 (Trpm4) Channel

(2012) Seung Kyoon Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sulfonylurea Receptor 1 in Central Nervous System Injury: A Focused Review

(2012) J Marc Simard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop

(2011) Yunlei Yang et al.   CELL

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Transient Receptor Potential Channel M4 and M5 in Magnocellular Cells in Rat Supraoptic and Paraventricular Nuclei

(2011) R. Teruyama et al.   JOURNAL OF NEUROENDOCRINOLOGY

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

AMP-activated protein kinase activates neuropeptide Y neurons in the hypothalamic arcuate nucleus to increase food intake in rats

(2011) Daisuke Kohno et al.   NEUROSCIENCE LETTERS

Selective T-Type Calcium Channel Block in Thalamic Neurons Reveals Channel Redundancy and Physiological Impact of ITwindow

(2010) F. M. Dreyfus et al.   JOURNAL OF NEUROSCIENCE

Physiological Roles of the TRPM4 Channel Extracted from Background Currents

(2010) Romain Guinamard et al.   PHYSIOLOGY

AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons

(2009) Beth Ann Murphy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ghrelin in Central Neurons

(2009) F. Ferrini et al.   Current Neuropharmacology

Ghrelin in the regulation of body weight and metabolism

(2009) T.R. Castañeda et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Neuromedin B and Gastrin-Releasing Peptide Excite Arcuate Nucleus Neuropeptide Y Neurons in a Novel Transgenic Mouse Expressing Strong Renilla Green Fluorescent Protein in NPY Neurons

(2009) A. N. van den Pol et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms of microvascular failure in central nervous system injury—synergistic roles of NKCC1 and SUR1/TRPM4

(2009) J. Marc Simard et al.   JOURNAL OF NEUROSURGERY

Autoradiographic analysis of ghrelin receptors in the rat hypothalamus

(2008) Joanne A. Harrold et al.   BRAIN RESEARCH

Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance

(2008) Kristin A. Anderson et al.   Cell Metabolism

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE

Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons

(2007) Daisuke Kohno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS