Novel application of the published kinase inhibitor set to identify therapeutic targets and pathways in triple negative breast cancer subtypes

Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

(2015) Hassan Al-Ali et al.   ACS Chemical Biology

Metastasis-Free Interval Is Closely Related to Tumor Characteristics and Has Prognostic Value in Breast Cancer Patients with Distant Relapse

(2015) Hee Jun Kim et al.   Journal of Breast Cancer

Epithelial-Mesenchymal Transition Phenotype Is Associated with Clinicopathological Factors That Indicate Aggressive Biological Behavior and Poor Clinical Outcomes in Invasive Breast Cancer

(2015) Young Kyung Bae et al.   Journal of Breast Cancer

Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones

(2015) Yingpei He et al.   MOLECULAR BIOLOGY OF THE CELL

Comprehensive characterization of the Published Kinase Inhibitor Set

(2015) Jonathan M Elkins et al.   NATURE BIOTECHNOLOGY

Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells

(2015) Ashleigh R. Poh et al.   Oncotarget

Abstract 557: Identification of mitogen-activated protein kinases which are required for the growth of triple-negative breast cancers.

(2014) Graham M. Poage et al.   CANCER RESEARCH

Kinome-wide Functional Analysis Highlights the Role of Cytoskeletal Remodeling in Somatic Cell Reprogramming

(2014) Kumi Sakurai et al.   Cell Stem Cell

Collective and individual migration following the epithelial–mesenchymal transition

(2014) Ian Y. Wong et al.   NATURE MATERIALS

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(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multivariate biophysical markers predictive of mesenchymal stromal cell multipotency

(2014) Wong Cheng Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Morphometric Analysis in Cellular Behaviors: Shape and Size Matter

(2013) Haiyang Yu et al.   Advanced Healthcare Materials

Survival in patients with metastatic recurrent breast cancer after adjuvant chemotherapy

(2012) Amye J. Tevaarwerk et al.   CANCER

The evolving landscape of protein kinases in breast cancer: Clinical implications

(2012) Alberto Ocaña et al.   CANCER TREATMENT REVIEWS

Defining the expressed breast cancer kinome

(2012) Alicia A Midland et al.   CELL RESEARCH

Regulation of EMT by TGFβ in cancer

(2012) Carl-Henrik Heldin et al.   FEBS LETTERS

A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma

(2012) Kian-Ngiap Chua et al.   PLoS One

Evidence for Phenotypic Plasticity in Aggressive Triple-Negative Breast Cancer: Human Biology Is Recapitulated by a Novel Model System

(2012) Nicholas C. D’Amato et al.   PLoS One

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Metastatic Triple-negative Breast Cancer

(2011) E.A. Rakha et al.   CLINICAL ONCOLOGY

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

GOBO: Gene Expression-Based Outcome for Breast Cancer Online

(2011) Markus Ringnér et al.   PLoS One

Inhibition of Platelet-Derived Growth Factor Receptor Signaling Regulates Oct4 and Nanog Expression, Cell Shape, and Mesenchymal Stem Cell Potency

(2011) Stephen G. Ball et al.   STEM CELLS

Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk

(2010) Lyndsay V Rhodes et al.   Molecular Cancer

The (un)targeted cancer kinome

(2010) Oleg Fedorov et al.   Nature Chemical Biology

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

(2010) J. H. Taube et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology, Metastatic Patterns, and Treatment of Patients with Triple-Negative Breast Cancer

(2009) Carey K. Anders et al.   Clinical Breast Cancer