Article
Nutrition & Dietetics
Jolanta Lis-Kuberka, Marta Berghausen-Mazur, Magdalena Orczyk-Pawilowicz
Summary: The study found that gestational diabetes mellitus (GDM) does not have a significant impact on the immunological quality of early milk, and there are slight differences in lactoferrin and immunoglobulin concentrations between hyperglycemic and normoglycemic mothers.
Article
Pharmacology & Pharmacy
Ivana Kacirova, Milan Grundmann, Hana Brozmanova
Summary: The study found significant correlations between milk/maternal serum concentration ratio and infant/maternal serum concentration ratio. Valproic acid concentrations in milk and infant serum did not reach the lower limit of the reference range for the general epileptic population, indicating that routine monitoring of serum concentrations of breastfed infants is not necessary.
Article
Chemistry, Multidisciplinary
Jintao Lu, Dan Zhang, Xiaomeng Zhang, Rina Sa, Xiaofang Wang, Huanzhang Wu, Zhijian Lin, Bing Zhang
Summary: This study investigated the interactions between citrus herbs and drugs, identifying shared potential active compounds and verifying the predictions through molecular docking and cell experiments. Further clinical and experimental evidence is needed to support these findings.
Article
Nursing
Sourabh Dutta, Bhabatosh Das, Tarini Shankar Ghosh, Shakti Kumar, Raj Kumari Kaushal, Pallab Ray, Vanita Suri, Gopinath Balakrish Nair
Summary: This study describes the milk microbiota of healthy North Indian women, showing that their milk microbiome is dominated by Pseudomonas, but with high diversity.
JOURNAL OF HUMAN LACTATION
(2023)
Article
Biochemistry & Molecular Biology
Maria del Mar Camacho, Juan Jose Martinez-Lahuerta, Eva Garcia-Martinez, Marta Igual, Nuria Martinez-Navarrete
Summary: This study collected data on the levels of vitamin C (VC) and naringenin (NAG) in the blood serum of 11 volunteers before and after consuming two different grapefruit juices. The results showed that the relative increases of VC and NAG in the blood serum after consuming grapefruit juices were 12% and 28%, respectively, while the increase in radical scavenging ability (RSA) was 26%. The bioavailability of VC was quantified as 1.529 +/- 0.002 mg VC/L serum per 100 mg of VC ingested.
Article
Public, Environmental & Occupational Health
Julie P. P. Smith, Alessandro Iellamo, Tuan T. T. Nguyen, Roger Mathisen
Summary: The Mothers' Milk Tool was developed to highlight the economic value of women's unpaid care work through breastfeeding. This manuscript describes its development and key features, and reports results for selected countries.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Pharmacology & Pharmacy
Ivana Kacirova, Milan Grundmann, Hana Brozmanova
Summary: The study found that the concentration of levetiracetam in maternal serum was similar to that in umbilical cord, higher in breastmilk compared to maternal serum, but significantly lower in infant serum. Breastfed infants had levetiracetam concentrations below the reference range used for the general population of epileptics.
Article
Nutrition & Dietetics
Britt J. van Keulen, Michelle Romijn, Albert Bondt, Kelly A. Dingess, Eva Kontopodi, Karlijn van der Straten, Maurits A. den Boer, Judith A. Burger, Meliawati Poniman, Berend J. Bosch, Philip J. M. Brouwer, Christianne J. M. de Groot, Max Hoek, Wentao Li, Dasja Pajkrt, Rogier W. Sanders, Anne Schoonderwoerd, Sem Tamara, Rian A. H. Timmermans, Gestur Vidarsson, Koert J. Stittelaar, Theo T. Rispens, Kasper A. Hettinga, Marit J. van Gils, Albert J. R. Heck, Johannes B. van Goudoever
Summary: The study found that human milk from mothers who recovered from COVID-19 contains SARS-CoV-2 specific antibodies, which retained neutralization capacity after pasteurization using High Pressure Pasteurization (HPP). This suggests a safe and effective immunization strategy post-HPP.
Article
Medicine, Research & Experimental
Ivana Kacirova, Milan Grundmann, Hana Brozmanova
Summary: This study analysed the concentrations of lamotrigine in maternal serum, colostrum, and serum of breastfed newborns. The findings showed that exposure to lamotrigine in breastfed newborns is lower than exposure during pregnancy. However, the concentrations of lamotrigine in both maternal serum and milk significantly increase after delivery. This may be due to the immature function of eliminating enzymes in newborns. Therefore, it is not mandatory to monitor the serum concentrations of lamotrigine in breastfed newborns, but analysis should be conducted if signs of possible adverse events are noted.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Food Science & Technology
Huijuan Ruan, Qingya Tang, Xuan Zhao, Yajie Zhang, Xuelin Zhao, Yi Xiang, Wei Geng, Yi Feng, Wei Cai
Summary: This study found that the levels of osteopontin (OPN) in breast milk of Chinese mothers showed dynamic changes with the extension of lactation time and were related to the mother's body composition.
FOOD SCIENCE AND HUMAN WELLNESS
(2022)
Article
Nutrition & Dietetics
Francesca Bravi, Matteo Di Maso, Simone R. B. M. Eussen, Carlo Agostoni, Guglielmo Salvatori, Claudio Profeti, Paola Tonetto, Pasqua Anna Quitadamo, Iwona Kazmierska, Elisabetta Vacca, Adriano Decarli, Bernd Stahl, Enrico Bertino, Guido E. Moro, Monica Ferraroni
Summary: The study identified five different dietary patterns in breast milk, which were associated with fatty acids, particularly omega-3 and its subcomponents. The results suggest that maternal dietary habits during breastfeeding may influence human milk composition.
Review
Nutrition & Dietetics
Deepti Khanna, Menaka Yalawar, Gaurav Verma, Shavika Gupta
Summary: The purpose of this systematic review was to understand the composition of Indian mothers' milk and assess changes over the past 100 years. The review identified 34 relevant studies and found variations in the levels of fat, protein, and lactose in different stages of milk. Factors such as maternal nutrition, diet, socioeconomic status, and regional differences were also found to influence milk composition.
Article
Nursing
Hongyu Huang, Mingzhe Ning, Jing Feng, Jie Chen, Yimin Dai, Yali Hu, Yi-Hua Zhou
Summary: This study aimed to quantify viral antigens and viral loads of hepatitis B virus in human milk samples from infected mothers. Results showed relatively low levels of viral markers in the milk compared to maternal circulation levels, with no correlation between viral levels in milk and blood.
JOURNAL OF HUMAN LACTATION
(2022)
Review
Immunology
Gatien A. G. Lokossou, Leonce Kouakanou, Anne Schumacher, Ana C. Zenclussen
Summary: Breastfeeding has long-term benefits for both children and mothers, reducing the risks of infectious and non-communicable diseases. The components in breast milk play important roles in disease protection and immune system development in newborns.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Applied
Sabrina H. Bilston-John, Ardra Narayanan, Ching Tat Lai, Alethea Rea, John Joseph, Donna T. Geddes
Summary: The study examined the daily and within-feed variations of macro- and trace-elements in human milk, finding significant differences in intake estimates when using morning pre-feed samples compared to measured 24-hour intake. Standardized sampling protocols with large sample volumes and multiple collections over 24-hours are recommended to provide a more accurate calculation of infant intake of macro- and trace-elements in human milk.
Article
Biochemistry & Molecular Biology
Urszula Marzec-Wroblewska, Piotr Kaminski, Pawel Lakota, Marek Szymanski, Karolina Wasilow, Grzegorz Ludwikowski, Leszek Jerzak, Tomasz Stuczynski, Alina Wozniak, Adam Bucinski
BIOLOGICAL TRACE ELEMENT RESEARCH
(2019)
Article
Chemistry, Analytical
Mariusz Zapadka, Mateusz Kaczmarek, Bogumila Kupcewicz, Przemyslaw Dekowski, Agata Walkowiak, Adam Kokotkiewicz, Maria Luczkiewicz, Adam Bucinski
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2019)
Article
Medicine, Research & Experimental
Anna Badura, Urszula Marzec-Wroblewska, Piotr Kaminski, Pawel Lakota, Grzegorz Ludwikowski, Marek Szymanski, Karolina Wasilow, Andzelika Lorenc, Adam Bucinski
JOURNAL OF APPLIED BIOMEDICINE
(2019)
Article
Chemistry, Medicinal
Anna Jesionek, Adam Kokotkiewicz, Anna Mikosik-Roczynska, Klaudia Ciesielska-Figlon, Piotr Luczkiewicz, Adam Bucinski, Agnieszka Daca, Jacek M. Witkowski, Ewa Bryl, Bozena Zabiegala, Maria Luczkiewicz
Article
Biotechnology & Applied Microbiology
A. Badura, J. Krysinski, A. Nowaczyk, A. Bucinski
Summary: This study successfully used artificial neural networks to predict the biological activity of chemical compounds, with regression and classification models showing high predictive accuracy in determining antimicrobial properties. Three-dimensional models constructed with computational chemistry methods allowed the transformation of chemical information into useful numerical values, increasing experimental efficiency.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Adam Kokotkiewicz, Bozena Zabiegala, Pawel Kubica, Agnieszka Szopa, Adam Bucinski, Halina Ekiert, Maria Luczkiewicz
Summary: Microshoot cultures of Verbena officinalis in temporary immersion bioreactors were investigated for essential oil content and volatile fraction composition. Results showed variations in essential oil content and composition under different culture conditions.
PLANT CELL TISSUE AND ORGAN CULTURE
(2021)
Article
Chemistry, Multidisciplinary
Anna Badura, Jerzy Krysinski, Alicja Nowaczyk, Adam Bucinski
Summary: The study utilized artificial neural networks to investigate the antibacterial activity of imidazole derivatives against Staphylococcus aureus, resulting in the development of highly predictive regression and classification models. These models proved useful in determining the antibacterial properties of quaternary ammonium salts against S. aureus, showcasing the potential of ANNs in supporting synthesis design and the search for new antimicrobial substances.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Food Science & Technology
Adam Kokotkiewicz, Anna Badura, Zaneta Tabaczynska, Andzelika Lorenc, Adam Bucinski, Maria Luczkiewicz
Summary: The study optimized parameters of conventional hydrodistillation and simultaneous distillation-extraction to obtain phthalide-enriched fractions of celery seeds. A positive correlation was shown between hydrodistillation time and improved essential oil and phthalide yields, with comminuted seeds yielding higher phthalide content in the essential oil. Changing distillation mode from hydrodistillation to simultaneous distillation-extraction significantly increased oil yield of whole seeds while maintaining high phthalide content.
POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES
(2021)
Article
Automation & Control Systems
Anna Badura, Jerzy Krysinski, Alicja Nowaczyk, Adam Bucinski
Summary: The article uses artificial neural networks to predict the antifungal properties of quaternary ammonium salts against Candida albicans. The models achieved high predictive ability and accurately classified the compounds into active or inactive.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
(2022)
Article
Biochemistry & Molecular Biology
Milena Polumackanycz, Mateusz Kaszuba, Agnieszka Konopacka, Urszula Marzec-Wroblewska, Marek Wesolowski, Krzysztof Waleron, Adam Bucinski, Agnieszka Viapiana