Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study

Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition

(2017) Rebecca F. Gottesman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system

(2016) Nilima Biswas et al.   BMC Medical Genetics

Plasma amyloid beta peptides: an Alzheimer’s conundrum or a more accessible Alzheimer’s biomarker?

(2016) Anne Poljak et al.   Expert Review of Neurotherapeutics

Perilipin 2 and Age-Related Metabolic Diseases: A New Perspective

(2016) Maria Conte et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

SORL1 gene, plasma biomarkers, and the risk of Alzheimer’s disease for the Han Chinese population in Taiwan

(2016) Cheng-Ta Chou et al.   Alzheimers Research & Therapy

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

(2016) Johanna Jakobsdottir et al.   PLoS Genetics

Plasma amyloid beta peptides: an Alzheimer’s conundrum or a more accessible Alzheimer’s biomarker?

(2016) Anne Poljak et al.   Expert Review of Neurotherapeutics

The Emerging Role of Tetraspanins in the Proteolytic Processing of the Amyloid Precursor Protein

(2016) Lisa Seipold et al.   Frontiers in Molecular Neuroscience

Age-dependent inverse correlations in CSF and plasma amyloid-β(1–42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice

(2016) Soo Min Cho et al.   Scientific Reports

Plasma β-amyloid in Alzheimer’s disease and vascular disease

(2016) Shorena Janelidze et al.   Scientific Reports

Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study

(2015) Vincent Chouraki et al.   Alzheimers & Dementia

Convergent genetic and expression data implicate immunity in Alzheimer's disease

(2015) Lesley Jones et al.   Alzheimers & Dementia

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

Age and amyloid effects on human central nervous system amyloid-beta kinetics

(2015) Bruce W. Patterson et al.   ANNALS OF NEUROLOGY

Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis

(2015) Celeste M. Karch et al.   BIOLOGICAL PSYCHIATRY

Genome-Wide Association Analysis of Plasma B–Type Natriuretic Peptide in BlacksCLINICAL PERSPECTIVE

(2015) Solomon K. Musani et al.   Circulation-Cardiovascular Genetics

Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease

(2015) Robert Baranello et al.   Current Alzheimer Research

Improvement of Age-Related Memory Impairment with Infusion of Young Plasma: A Role for the Peripheral Amyloid Sink?

(2015) Ali Jawaid et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Factors Responsible for Plasma β-Amyloid Accumulation in Chronic Kidney Disease

(2015) Janine Gronewold et al.   MOLECULAR NEUROBIOLOGY

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome

(2015) Nicole Schupf et al.   NEUROBIOLOGY OF AGING

Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice

(2015) Feng-Shiun Shie et al.   PLoS One

Activation of the factor XII-driven contact system in Alzheimer’s disease patient and mouse model plasma

(2015) Daria Zamolodchikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Additional mechanisms conferring genetic susceptibility to Alzheimer’s disease

(2015) Miguel Calero et al.   Frontiers in Cellular Neuroscience

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease

(2015) Zhentao Zhang et al.   Nature Communications

The tetraspanin web revisited by super-resolution microscopy

(2015) Malou Zuidscherwoude et al.   Scientific Reports

Impaired Aβ clearance: a potential link between atherosclerosis and Alzheimer’s disease

(2015) Ajay Gupta et al.   Frontiers in Aging Neuroscience

Genome-Wide Association Analysis of Plasma B–Type Natriuretic Peptide in BlacksCLINICAL PERSPECTIVE

(2015) Solomon K. Musani et al.   Circulation-Cardiovascular Genetics

Plasma Aβ but Not Tau is Related to Brain PiB Retention in Early Alzheimer’s Disease

(2014) Kai-Yuan Tzen et al.   ACS Chemical Neuroscience

Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia

(2014) Jeannette Simino et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Arguments for the sake of endophenotypes: Examining common misconceptions about the use of endophenotypes in psychiatric genetics

(2014) David C. Glahn et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Linkage analysis incorporating gene–age interactions identifies seven novel lipid loci: The Family Blood Pressure Program

(2014) Jeannette Simino et al.   ATHEROSCLEROSIS

Structural and Functional Assessment of Perilipin 2 Lipid Binding Domain(s)

(2014) Charles P. Najt et al.   BIOCHEMISTRY

SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease

(2014) Alfredo Ramirez et al.   HUMAN MOLECULAR GENETICS

Novel Interactive Partners of Neuroligin 3: New Aspects for Pathogenesis of Autism

(2014) Chen Shen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Suppression of InsP3 Receptor-Mediated Ca2+ Signaling Alleviates Mutant Presenilin-Linked Familial Alzheimer's Disease Pathogenesis

(2014) D. Shilling et al.   JOURNAL OF NEUROSCIENCE

Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women

(2014) B. Siegerink et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly

(2014) V Chouraki et al.   MOLECULAR PSYCHIATRY

Calcium regulates the interaction of amyloid precursor protein with Homer3 protein

(2014) Elli Kyratzi et al.   NEUROBIOLOGY OF AGING

Midlife Hypertension and 20-Year Cognitive Change

(2014) Rebecca F. Gottesman et al.   JAMA Neurology

Tetraspanins in Extracellular Vesicle Formation and Function

(2014) Zoraida Andreu et al.   Frontiers in Immunology

Identification of rare variants in Alzheimer’s disease

(2014) Jenny Lord et al.   Frontiers in Genetics

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

(2013) Alan Rembach et al.   Alzheimers & Dementia

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

(2013) Shanker Swaminathan et al.   Alzheimers & Dementia

The minor allele of the missense polymorphism Ser251Pro in perilipin 2 (PLIN2) disrupts an α-helix, affects lipolysis, and is associated with reduced plasma triglyceride concentration in humans

(2013) Joëlle Magné et al.   FASEB JOURNAL

Genome-Wide Association Study on Plasma Levels of Midregional-Proadrenomedullin and C-Terminal-Pro-Endothelin-1

(2013) Niek Verweij et al.   HYPERTENSION

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Replication Study Confirms Link between TSPAN18 Mutation and Schizophrenia in Han Chinese

(2013) Jianmin Yuan et al.   PLoS One

Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium

(2013) Megan L. Grove et al.   PLoS One

Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarker

(2013) Jon B Toledo et al.   Alzheimers Research & Therapy

Alzheimer's disease-associated peptide Aβ42 mobilizes ER Ca2+ via InsP3R-dependent and -independent mechanisms

(2013) Laura E. Jensen et al.   Frontiers in Molecular Neuroscience

Hot topics in epigenetic mechanisms of aging: 2011

(2012) María Berdasco et al.   AGING CELL

Plasma Amyloid-β as a Predictor of Dementia and Cognitive Decline

(2012) Alain Koyama et al.   ARCHIVES OF NEUROLOGY

An integrative variant analysis suite for whole exome next-generation sequencing data

(2012) Danny Challis et al.   BMC BIOINFORMATICS

Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI

(2011) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

Association of Plasma β-Amyloid Level and Cognitive Reserve With Subsequent Cognitive Decline

(2011) Kristine Yaffe   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels

(2011) C. Y. Daniel Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

(2011) Wei-Hua Yue et al.   NATURE GENETICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Association of Plasma Aß Peptides with Blood Pressure in the Elderly

(2011) Jean-Charles Lambert et al.   PLoS One

Common variants in the haemostatic gene pathway contribute to risk of early-onset myocardial infarction in the Italian population

(2011) Ilaria Guella et al.   THROMBOSIS AND HAEMOSTASIS

Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities

(2011) Matthew N Bainbridge et al.   GENOME BIOLOGY

Genome-wide association reveals genetic effects on human Aβ 42 and τ protein levels in cerebrospinal fluids: a case control study

(2010) Mi-Ryung Han et al.   BMC Neurology

Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β-peptide elimination from the brain

(2010) Berislav V. Zlokovic et al.   JOURNAL OF NEUROCHEMISTRY

Death-Associated Protein Kinase-Mediated Cell Death Modulated by Interaction with DANGER

(2010) B. N. Kang et al.   JOURNAL OF NEUROSCIENCE

Assessment of activation of the plasma kallikrein-kinin system in frontal and temporal cortex in Alzheimer's disease and vascular dementia

(2010) Emma L. Ashby et al.   NEUROBIOLOGY OF AGING

Association between variants in IDE-KIF11-HHEX and plasma amyloid β levels

(2010) Christiane Reitz et al.   NEUROBIOLOGY OF AGING

Genome-wide association study of CSF biomarkers A 1-42, t-tau, and p-tau181p in the ADNI cohort

(2010) S. Kim et al.   NEUROLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Adipophilin affects the expression of TNF-α, MCP-1, and IL-6 in THP-1 macrophages

(2009) F. L. Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Association of plasma amyloid   with risk of dementia: The prospective Three-City Study

(2009) J. -C. Lambert et al.   NEUROLOGY

Deficiency of Adipose Differentiation-Related Protein Impairs Foam Cell Formation and Protects Against Atherosclerosis

(2008) Antoni Paul et al.   CIRCULATION RESEARCH

MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels

(2008) Derek B. Oien et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic Effect on Blood Pressure Is Modulated by Age

(2008) Gang Shi et al.   HYPERTENSION

Genetic deletion or antagonism of kinin B1 and B2 receptors improves cognitive deficits in a mouse model of Alzheimer's disease

(2007) R.D.S. Prediger et al.   NEUROSCIENCE