Effects of Vernonia cinerea Compounds on Drug-metabolizing Cytochrome P450s in Human Liver Microsomes

An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure

(2016) Dany Spaggiari et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibition effects of Vernonia cinerea active compounds against cytochrome P450 2A6 and human monoamine oxidases, possible targets for reduction of tobacco dependence

(2015) Aruna Prasopthum et al.   Drug Metabolism and Pharmacokinetics

Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma

(2015) Gabriella Miklossy et al.   JOURNAL OF MEDICINAL CHEMISTRY

A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies

(2014) Dany Spaggiari et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A review on ethno-medicinal uses and pharmacology ofVernonia cinereaLess.

(2014) Nittya K. Dogra et al.   NATURAL PRODUCT RESEARCH

Cocktail-substrate Approach-based High-throughput Assay for Evaluation of Direct and Time-dependent Inhibition of Multiple Cytochrome P450 Isoforms

(2013) Kazumasa Kozakai et al.   Drug Metabolism and Pharmacokinetics

Evaluation of in vitro cytochrome P450 induction and inhibition activity of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber L.

(2013) Xue Fen Koe et al.   FOOD AND CHEMICAL TOXICOLOGY

A review of the medicinal potentials of plants of the genus Vernonia (Asteraceae)

(2013) Ngeh J. Toyang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacokinetic study of luteolin, apigenin, chrysoeriol and diosmetin after oral administration of Flos Chrysanthemi extract in rats

(2012) Zhongjian Chen et al.   FITOTERAPIA

Selective inhibition of methoxyflavonoids on human CYP1B1 activity

(2010) Hitomi Takemura et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure−Function Relationships of Inhibition of Human Cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 Flavonoid Derivatives

(2010) Tsutomu Shimada et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Vernonia cinerea Less. Inhibits Tumor Cell Invasion and Pulmonary Metastasis in C57BL/6 Mice

(2010) Poyil Pratheeshkumar et al.   INTEGRATIVE CANCER THERAPIES

Vernonia cinerea Less. supplementation and strenuous exercise reduce smoking rate: relation to oxidative stress status and beta-endorphin release in active smokers

(2010) Donrawee Leelarungrayub et al.   Journal of the International Society of Sports Nutrition

The relationship between fasting plasma concentrations of selected flavonoids and their ordinary dietary intake

(2009) Jie Cao et al.   BRITISH JOURNAL OF NUTRITION

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2

(2009) Shu-Feng Zhou et al.   DRUG METABOLISM REVIEWS

Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity

(2009) Yuka Kimura et al.   FOOD AND CHEMICAL TOXICOLOGY

Phytoestrogens as natural prodrugs in cancer prevention: dietary flavonoids

(2009) Randolph R. J. Arroo et al.   PHYTOCHEMISTRY REVIEWS

Identification of ginkgolide B metabolites in urine and rat liver cytochrome P450 enzymes responsible for their formation in vitro

(2008) Dian-lei WANG et al.   ACTA PHARMACOLOGICA SINICA