Nephron number, hypertension, and CKD: physiological and genetic insight from humans and animal models

Solitary Functioning Kidney in Children - A Follow-Up Study

(2017) Gabriel Kolvek et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Phenotyping by magnetic resonance imaging nondestructively measures glomerular number and volume distribution in mice with and without nephron reduction

(2016) Edwin J. Baldelomar et al.   KIDNEY INTERNATIONAL

Selection and Postoperative Care of the Living Donor

(2016) Dianne LaPointe Rudow et al.   MEDICAL CLINICS OF NORTH AMERICA

Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate

(2016) Morgan E. Grams et al.   NEW ENGLAND JOURNAL OF MEDICINE

Longitudinal study of living kidney donor glomerular dynamics after nephrectomy

(2015) Colin R. Lenihan et al.   JOURNAL OF CLINICAL INVESTIGATION

Shifting paradigms in eligibility criteria for live kidney donation: a systematic review

(2015) Ali R. Ahmadi et al.   KIDNEY INTERNATIONAL

Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease

(2015) Magda S.C. Fontes et al.   CardioRenal Medicine

Risk of End-Stage Renal Disease Following Live Kidney Donation

(2014) Abimereki D. Muzaale et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nephron Deficiency and Predisposition to Renal Injury in a Novel One-Kidney Genetic Model

(2014) X. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

(2014) B. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Risk of chronic kidney disease after cancer nephrectomy

(2014) Lin Li et al.   Nature Reviews Nephrology

A novel heart failure mice model of hypertensive heart disease by angiotensin II infusion, nephrectomy, and salt loading

(2013) Yasumasa Tsukamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Wireless Amplified Nuclear MR Detector (WAND) for High-Spatial-Resolution MR Imaging of Internal Organs: Preclinical Demonstration in a Rodent Model

(2013) Chunqi Qian et al.   RADIOLOGY

Long-Term Consequences of Uninephrectomy in Male and Female Rats

(2012) Isabel Rodríguez-Gómez et al.   HYPERTENSION

MWF rats with spontaneous albuminuria inherit a reduced efficiency of nephron induction during early nephrogenesis in comparison to SHR rats

(2012) Leonard Schulte et al.   JOURNAL OF HYPERTENSION

Renoprotective Effects of Sildenafil in DOCA-Salt Hypertensive Rats

(2012) Eun Hui Bae et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Outcome of the living kidney donor

(2012) P. Delanaye et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Safety in glomerular numbers

(2012) Michiel F. Schreuder   PEDIATRIC NEPHROLOGY

Compensatory Growth of Congenital Solitary Kidneys in Pigs Reflects Increased Nephron Numbers Rather Than Hypertrophy

(2012) Stefan H. van Vuuren et al.   PLoS One

Using mouse models to understand normal and abnormal urogenital tract development

(2012) Cathy Mendelsohn   Organogenesis

Autosomal Dominant Mutation in the Signal Peptide of Renin in a Kindred With Anemia, Hyperuricemia, and CKD

(2011) Bodo B. Beck et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Age-Related Pathophysiological Changes in Rats with Unilateral Renal Agenesis

(2011) Kohei AMAKASU et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis

(2011) Pawaree Saisawat et al.   KIDNEY INTERNATIONAL

Human nephron number: implications for health and disease

(2011) John F. Bertram et al.   PEDIATRIC NEPHROLOGY

Prematurity in mice leads to reduction in nephron number, hypertension, and proteinuria

(2011) Cary Stelloh et al.   Translational Research

PAX2 gene mutations in pediatric and young adult transplant recipients: kidney and urinary tract malformations without ocular anomalies

(2010) S Negrisolo et al.   CLINICAL GENETICS

Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model

(2010) Asada Leelahavanichkul et al.   KIDNEY INTERNATIONAL

Congenital versus acquired solitary kidney: is the difference relevant?

(2010) P. Abou Jaoude et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Genetics of congenital anomalies of the kidney and urinary tract

(2010) Renfang Song et al.   PEDIATRIC NEPHROLOGY

HNF1B alterations associated with congenital anomalies of the kidney and urinary tract

(2010) Makiko Nakayama et al.   PEDIATRIC NEPHROLOGY

The many faces of RET dysfunction in kidney

(2010) Sanjay Jain   Organogenesis

Dominant Renin Gene Mutations Associated with Early-Onset Hyperuricemia, Anemia, and Chronic Kidney Failure

(2009) Martina Živná et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Is Low Birth Weight an Antecedent of CKD in Later Life? A Systematic Review of Observational Studies

(2009) Sarah L. White et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Advances in early kidney specification, development and patterning

(2009) G. R. Dressler   DEVELOPMENT

Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development

(2009) K. J. Reidy et al.   DEVELOPMENT

Ret-Dependent Cell Rearrangements in the Wolffian Duct Epithelium Initiate Ureteric Bud Morphogenesis

(2009) Xuan Chi et al.   DEVELOPMENTAL CELL

Experimental animal models of hypertension

(2009) Kiran V. Sarikonda et al.   Journal of the American Society of Hypertension

Renal outcome in patients with congenital anomalies of the kidney and urinary tract

(2009) Simone Sanna-Cherchi et al.   KIDNEY INTERNATIONAL

Long-Term Consequences of Kidney Donation

(2009) Hassan N. Ibrahim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional analysis of BMP4 mutations identified in pediatric CAKUT patients

(2009) Mansoureh Tabatabaeifar et al.   PEDIATRIC NEPHROLOGY

Mutations in the ROBO2 and SLIT2 genes are rare causes of familial vesico-ureteral reflux

(2009) Shulu Zu et al.   PEDIATRIC NEPHROLOGY

Differential Effects of Clinical Doses of Antenatal Betamethasone on Nephron Endowment and Glomerular Filtration Rate in Adult Sheep

(2009) Jie Zhang et al.   Reproductive Sciences

Morbidity and Mortality in 1022 Consecutive Living Donor Nephrectomies: Benefits of a Living Donor Registry

(2009) Geir Mjøen et al.   TRANSPLANTATION

Effect of Intrauterine Growth Restriction on Kidney Function at Young Adult Age: The Nord Trøndelag Health (HUNT 2) Study

(2008) Stein Hallan et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

(2008) Akio Kobayashi et al.   Cell Stem Cell

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli

(2008) J. E. Pitera et al.   HUMAN MOLECULAR GENETICS

ROBO2 Gene Variants Are Associated with Familial Vesicoureteral Reflux

(2008) A. M. Bertoli-Avella et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development

(2008) S. Weber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Loss of Sprouty1 Rescues Renal Agenesis Caused by Ret Mutation

(2008) E. J. Rozen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Downregulation of Spry-1, an inhibitor of GDNF/Ret, causes angiotensin II-induced ureteric bud branching

(2008) Ihor V. Yosypiv et al.   KIDNEY INTERNATIONAL

Renal agenesis and unilateral nephrectomy: what are the risks of living with a single kidney?

(2008) Shivaram Hegde et al.   PEDIATRIC NEPHROLOGY

Kidney biopsies can be used for estimations of glomerular number and volume: a pig study

(2008) Anders Bergh Lødrup et al.   VIRCHOWS ARCHIV

Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia

(2007) Scott Boyle et al.   DEVELOPMENTAL BIOLOGY