Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia

Stress-activatedmiR-21/miR-21*in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption

(2016) Nicolas Calo et al.   GUT

Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis

(2016) Fujun Yu et al.   MEDIATORS OF INFLAMMATION

Alternative splicing generates novel Fads3 transcript in mice

(2016) Ji Yao Zhang et al.   MOLECULAR BIOLOGY REPORTS

β-ionone modulates the expression of miRNAs and genes involved in the metastatic phenotype of microdissected persistent preneoplastic lesions in rats submitted to hepatocarcinogenesis

(2016) Kelly Silva Furtado et al.   MOLECULAR CARCINOGENESIS

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Normal weight dyslipidemia: Is it all about the liver?

(2016) David Højland Ipsen et al.   Obesity

MicroRNA-27a decreases the level and efficiency of the LDL receptor and contributes to the dysregulation of cholesterol homeostasis

(2015) M. Lucrecia Alvarez et al.   ATHEROSCLEROSIS

Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population

(2015) Holly Rutledge et al.   BMC GENOMICS

Hepatitis C Virus RNA Functionally Sequesters miR-122

(2015) Joseph M. Luna et al.   CELL

Role of microRNA-30c in lipid metabolism, adipogenesis, cardiac remodeling and cancer

(2015) Sara Irani et al.   CURRENT OPINION IN LIPIDOLOGY

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

(2015) Leigh Goedeke et al.   NATURE MEDICINE

Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs

(2015) Sara R. Selitsky et al.   mBio

Effect of miR-34a in regulating steatosis by targeting PPARα expression in nonalcoholic fatty liver disease

(2015) Jiexia Ding et al.   Scientific Reports

Addressing Bias in Small RNA Library Preparation for Sequencing: A New Protocol Recovers MicroRNAs that Evade Capture by Current Methods

(2015) Jeanette Baran-Gale et al.   Frontiers in Genetics

Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia

(2014) Raymond Ng et al.   HEPATOLOGY

Aberrant miR199a-5p/caveolin1/PPARα axis in hepatic steatosis

(2014) Bo Li et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

(2014) Yue-Mei Fan et al.   Scientific Reports

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis

(2014) Tangi L. Smallwood et al.   G3-Genes Genomes Genetics

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Hepatitis C virus induced up-regulation of microRNA-27: A novel mechanism for hepatic steatosis

(2013) Ragunath Singaravelu et al.   HEPATOLOGY

MicroRNA-27a Regulates Lipid Metabolism and Inhibits Hepatitis C Virus Replication in Human Hepatoma Cells

(2013) T. Shirasaki et al.   JOURNAL OF VIROLOGY

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE −/− Mice

(2013) Takahiro Horie et al.   Journal of the American Heart Association

The magic and mystery of MicroRNA-27 in atherosclerosis

(2012) Wu-Jun Chen et al.   ATHEROSCLEROSIS

High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population

(2012) Karen L. Svenson et al.   GENETICS

MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia

(2012) Kasey C. Vickers et al.   HEPATOLOGY

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs

(2012) Xin Lai et al.   NUCLEIC ACIDS RESEARCH

Hyperlipidemia as a Risk Factor for Cardiovascular Disease

(2012) Robert H. Nelson   PRIMARY CARE

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor  -Klotho

(2012) T. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

(2011) Emma Raitoharju et al.   ATHEROSCLEROSIS

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

(2011) Katey J. Rayner et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

PPARα Is Regulated by miR-21 and miR-27b in Human Liver

(2011) Katsuhiko Kida et al.   PHARMACEUTICAL RESEARCH

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

MiRNA–miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features

(2010) Juan Xu et al.   NUCLEIC ACIDS RESEARCH

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

(2009) Xia Yang et al.   NATURE GENETICS

TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

(2009) B Wang et al.   ONCOGENE

A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia

(2009) Christopher L. Plaisier et al.   PLoS Genetics

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE