What factors determine the stability of a weak protein–protein interaction in a charged aqueous droplet?

Increasing Ubiquitin Ion Resistance to Unfolding in the Gas Phase Using Chloride Adduction: Preserving More “Native-Like” Conformations Despite Collisional Activation

(2016) Nicole D. Wagner et al.   ANALYTICAL CHEMISTRY

New mechanisms of macroion-induced disintegration of charged droplets

(2016) Styliani Consta et al.   CHEMICAL PHYSICS LETTERS

Characterization of “Star” Droplet Morphologies Induced by Charged Macromolecules

(2016) Mahmoud Sharawy et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Stability of a Transient Protein Complex in a Charged Aqueous Droplet with Variable pH

(2016) Myong In Oh et al.   Journal of Physical Chemistry Letters

Native Mass Spectrometry: What is in the Name?

(2016) Aneika C. Leney et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

On the preservation of non-covalent protein complexes during electrospray ionization

(2016) Konstantin Chingin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Correlating Droplet Size with Temperature Changes in Electrospray Source by Optical Methods

(2015) Antonin Soleilhac et al.   ANALYTICAL CHEMISTRY

Mass Spectrometry of Protein Complexes: From Origins to Applications

(2015) Shahid Mehmood et al.   Annual Review of Physical Chemistry

Determination of thermodynamic and kinetic properties of biomolecules by mass spectrometry

(2015) Basri Gülbakan et al.   CURRENT OPINION IN BIOTECHNOLOGY

Effect of solvent on the charging mechanisms of poly(ethylene glycol) in droplets

(2015) Sepideh Soltani et al.   JOURNAL OF CHEMICAL PHYSICS

Water-Mediated Dimerization of Ubiquitin Ions Captured by Cryogenic Ion Mobility-Mass Spectrometry

(2015) Kelly A. Servage et al.   Journal of Physical Chemistry Letters

Applying mass spectrometry to study non-covalent biomolecule complexes

(2015) Fan Chen et al.   MASS SPECTROMETRY REVIEWS

How do non-covalent complexes dissociate in droplets? A case study of the desolvation of dsDNA from a charged aqueous nanodrop

(2015) Mahmoud Sharawy et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Chemical cross-linking and native mass spectrometry: A fruitful combination for structural biology

(2015) Andrea Sinz et al.   PROTEIN SCIENCE

DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin

(2015) Urszula Nowicka et al.   STRUCTURE

Effect of counterions on the charging mechanisms of a macromolecule in aqueous nanodrops

(2014) Mahmoud Sharawy et al.   JOURNAL OF CHEMICAL PHYSICS

Charge Reduction Stabilizes Intact Membrane Protein Complexes for Mass Spectrometry

(2014) Shahid Mehmood et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disintegration mechanisms of charged nanodroplets: novel systems for applying methods of activated processes

(2014) Styliani Consta et al.   MOLECULAR SIMULATION

Membrane proteins bind lipids selectively to modulate their structure and function

(2014) Arthur Laganowsky et al.   NATURE

DNA Oligonucleotides: A Model System with Tunable Binding Strength to Study Monomer–Dimer Equilibria with Electrospray Ionization-Mass Spectrometry

(2013) Konstantin Barylyuk et al.   ANALYTICAL CHEMISTRY

Fluorometric Measurement and Modeling of Droplet Temperature Changes in an Electrospray Plume

(2013) Stephen C. Gibson et al.   ANALYTICAL CHEMISTRY

Conformational thermodynamics of metal-ion binding to a protein

(2013) Amit Das et al.   CHEMICAL PHYSICS LETTERS

Variation of droplet acidity during evaporation

(2013) Anatoly Malevanets et al.   JOURNAL OF CHEMICAL PHYSICS

Classification of the ejection mechanisms of charged macromolecules from liquid droplets

(2013) Styliani Consta et al.   JOURNAL OF CHEMICAL PHYSICS

Effects of Metal Ion Adduction on the Gas-Phase Conformations of Protein Ions

(2013) Tawnya G. Flick et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Dramatically stabilizing multiprotein complex structure in the absence of bulk water using tuned Hofmeister salts

(2012) Linjie Han et al.   FARADAY DISCUSSIONS

Extension of the CHARMM general force field to sulfonyl-containing compounds and its utility in biomolecular simulations

(2012) Wenbo Yu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Do Charge State Signatures Guarantee Protein Conformations?

(2012) Zoe Hall et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Reliable Determinations of Protein–Ligand Interactions by Direct ESI-MS Measurements. Are We There Yet?

(2012) Elena N. Kitova et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

On the binding affinity of macromolecular interactions: daring to ask why proteins interact

(2012) P. L. Kastritis et al.   Journal of the Royal Society Interface

Two decades of studying non-covalent biomolecular assemblies by means of electrospray ionization mass spectrometry

(2012) G. R. Hilton et al.   Journal of the Royal Society Interface

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies

(2012) Rebecca J Rose et al.   NATURE METHODS

Investigation of stable and transient protein-protein interactions: Past, present, and future

(2012) Armand G. Ngounou Wetie et al.   PROTEOMICS

Charge state and adduct reduction in electrospray ionization–mass spectrometry using solvent vapor exposure

(2011) Jonathan T.S. Hopper et al.   ANALYTICAL BIOCHEMISTRY

Quantifying Protein–Protein Interactions Within Noncovalent Complexes Using Electrospray Ionization Mass Spectrometry

(2011) Elisabetta Boeri Erba et al.   ANALYTICAL CHEMISTRY

Noncovalent Dimerization of Ubiquitin

(2011) Zhu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

How Alkali Metal Ion Binding Alters the Conformation Preferences of Gramicidin A: A Molecular Dynamics and Ion Mobility Study

(2011) Liuxi Chen et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Bound Anions Differentially Stabilize Multiprotein Complexes in the Absence of Bulk Solvent

(2011) Linjie Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

What Happens to Hydrophobic Interactions during Transfer from the Solution to the Gas Phase? The Case of Electrospray-Based Soft Ionization Methods

(2011) Konstantin Barylyuk et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Simulating water with rigid non-polarizable models: a general perspective

(2011) Carlos Vega et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Transient protein-protein interactions

(2011) S. E. Acuner Ozbabacan et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Alternate Dissociation Pathways Identified in Charge-Reduced Protein Complex Ions

(2010) Kevin Pagel et al.   ANALYTICAL CHEMISTRY

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

(2009) Nelson P Barrera et al.   NATURE METHODS

Native mass spectrometry: a bridge between interactomics and structural biology

(2008) Albert J R Heck   NATURE METHODS