Phytochemicals for the Prevention of Photocarcinogenesis

Resveratrol-Loaded Liquid-Crystalline System Inhibits UVB-Induced Skin Inflammation and Oxidative Stress in Mice

(2016) Andressa T. Fujimura et al.   JOURNAL OF NATURAL PRODUCTS

Skin cancer risk in outdoor workers: a European multicenter case-control study

(2016) M. Trakatelli et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

The effects of quercetin-loaded PLGA-TPGS nanoparticles on ultraviolet B-induced skin damages in vivo

(2016) Xianbing Zhu et al.   Nanomedicine-Nanotechnology Biology and Medicine

The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes

(2016) Andreia Ascenso et al.   Oxidative Medicine and Cellular Longevity

Solar ultraviolet radiation in Africa: a systematic review and critical evaluation of the health risks and use of photoprotection

(2016) Robyn M. Lucas et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

What do we know about sulforaphane protection against photoaging?

(2016) Sohely Sikdar et al.   Journal of Cosmetic Dermatology

European Code against Cancer 4th Edition: Ultraviolet radiation and cancer

(2015) Rüdiger Greinert et al.   Cancer Epidemiology

Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans

(2015) E. V. Knatko et al.   Cancer Prevention Research

Microemulsion Using Polyoxyethylene Sorbitan Trioleate and Its Usage for Skin Delivery of Resveratrol to Protect Skin against UV-Induced Damage

(2015) Reiko Yutani et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis

(2015) J. Antoni Sirerol et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fisetin Ameliorated Photodamage by Suppressing the Mitogen-Activated Protein Kinase/Matrix Metalloproteinase Pathway and Nuclear Factor-κB Pathways

(2015) Hsiu-Mei Chiang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Flavonols Protect Against UV Radiation-Induced Thymine Dimer Formation in an Artificial Skin Mimic

(2015) Sabia Maini et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Photoprotection by Punica granatum seed oil nanoemulsion entrapping polyphenol-rich ethyl acetate fraction against UVB-induced DNA damage in human keratinocyte (HaCaT) cell line

(2015) Thaisa Baccarin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the US Population, 2012

(2015) Howard W. Rogers et al.   JAMA Dermatology

Apigenin Reactivates Nrf2 Anti-oxidative Stress Signaling in Mouse Skin Epidermal JB6 P + Cells Through Epigenetics Modifications

(2014) Ximena Paredes-Gonzalez et al.   AAPS Journal

In vivo human skin penetration of (–)-epigallocatechin-3-gallate from topical formulations

(2014) Santo Scalia et al.   ACTA PHARMACEUTICA

SIRT6 Promotes COX-2 Expression and Acts as an Oncogene in Skin Cancer

(2014) M. Ming et al.   CANCER RESEARCH

Cyclooxygenases: Mediators of UV-Induced Skin Cancer and Potential Targets for Prevention

(2014) Craig A. Elmets et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Role of Antioxidants in Skin Cancer Prevention and Treatment

(2014) Aleksandar Godic et al.   Oxidative Medicine and Cellular Longevity

Fisetin Inhibits UVB-induced Cutaneous Inflammation and Activation of PI3K/AKT/NFκB Signaling Pathways in SKH-1 Hairless Mice

(2014) Harish Chandra Pal et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Improvement of polyphenol properties upon glucosylation in a UV-induced skin cell ageing model

(2014) M. Nadim et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38  Signaling Pathway

(2013) K. Liu et al.   CANCER RESEARCH

Stability of sulforaphane for topical formulation

(2013) Stephen J. Franklin et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

NADPH oxidase is a novel target of delphinidin for the inhibition of UVB-induced MMP-1 expression in human dermal fibroblasts

(2013) Tae-Gyu Lim et al.   EXPERIMENTAL DERMATOLOGY

Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: Mitochondria mediated apoptotic signalling cascades

(2013) Sreemanti Das et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of pre- and post-treatment with plant polyphenols on human keratinocyte responses to solar UV

(2013) Alla I. Potapovich et al.   INFLAMMATION RESEARCH

Enhanced in vitro and in vivo skin deposition of apigenin delivered using ethosomes

(2013) Li-Na Shen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Luteolin suppresses UVB-induced photoageing by targeting JNK1 and p90RSK2

(2013) Sung H. Lim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Quercitrin protects skin from UVB-induced oxidative damage

(2013) Yuanqin Yin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Formulation of Microemulsion Systems for Dermal Delivery of Silymarin

(2012) Vipaporn Panapisal et al.   AAPS PHARMSCITECH

Development and Validation of a Simple and Rapid Liquid Chromatography Method for the Determination of Genistein in Skin Permeation Studies

(2012) Lorena Maione-Silva et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Src kinase is a direct target of apigenin against UVB-induced skin inflammation

(2012) Sanguine Byun et al.   CARCINOGENESIS

Decylglucoside-based microemulsions for cutaneous localization of lycopene and ascorbic acid

(2012) Dominique Pepe et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Validation of an LC Method to Determine Skin Retention Profile of Genistein from Nanoemulsions Incorporated in Hydrogels

(2012) B. A. de Vargas et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Evaluation of drug and sunscreen permeation via skin irradiated with UVA and UVB: Comparisons of normal skin and chronologically aged skin

(2012) Chi-Feng Hung et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The role of antioxidants in photoprotection: A critical review

(2012) Lucy Chen et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Resveratrate protects human skin from damage due to repetitive ultraviolet irradiation

(2012) Y. Wu et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Ethanol Extract of Peanut Sprout Induces Nrf2 Activation and Expression of Antioxidant and Detoxifying Enzymes in Human Dermal Fibroblasts: Implication for its Protection Against UVB-irradiated Oxidative Stress

(2012) Jee-Young Choi et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Differential Activation of Signaling Pathways by UVA and UVB Radiation in Normal Human Epidermal Keratinocytes†

(2012) Deeba N. Syed et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Luteolin Prevents Solar Radiation-Induced Matrix Metalloproteinase-1 Activation in Human Fibroblasts: A Role for p38 Mitogen-Activated Protein Kinase and Interleukin-20 Released from Keratinocytes

(2012) Ute Wölfle et al.   REJUVENATION RESEARCH

Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner

(2011) Srirupa Roy et al.   CARCINOGENESIS

Pterostilbene Is More Potent than Resveratrol in Preventing Azoxymethane (AOM)-Induced Colon Tumorigenesis via Activation of the NF-E2-Related Factor 2 (Nrf2)-Mediated Antioxidant Signaling Pathway

(2011) Yi-Siou Chiou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Silibinin Is a Potent Sensitizer of UVA Radiation-induced Oxidative Stress and Apoptosis in Human Keratinocyte HaCaT Cells†

(2011) Sreekanth Narayanapillai et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Pomegranate Fruit Extract Inhibits UVB-induced Inflammation and Proliferation by Modulating NF-κB and MAPK Signaling Pathways in Mouse Skin†

(2011) Naghma Khan et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Silymarin Protects Epidermal Keratinocytes from Ultraviolet Radiation-Induced Apoptosis and DNA Damage by Nucleotide Excision Repair Mechanism

(2011) Santosh K. Katiyar et al.   PLoS One

In vitro human skin permeation and cutaneous metabolism of catechins from green tea extract and green tea extract-loaded chitosan microparticles

(2011) W. Wisuitiprot et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Quercetin Potentiates UVB-Induced c-Fos Expression: Implications for Its Use as a Chemopreventive Agent

(2010) E. R. Olson et al.   Cancer Prevention Research

Green Tea Polyphenols Prevent UV-Induced Immunosuppression by Rapid Repair of DNA Damage and Enhancement of Nucleotide Excision Repair Genes

(2010) S. K. Katiyar et al.   Cancer Prevention Research

Luteolin Inhibits Protein Kinase C  and c-Src Activities and UVB-Induced Skin Cancer

(2010) S. Byun et al.   CANCER RESEARCH

Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation

(2010) M. Vaid et al.   CARCINOGENESIS

Resveratrol protects human keratinocytes HaCaT cells from UVA-induced oxidative stress damage by downregulating Keap1 expression

(2010) Yong Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ultraviolet light induces Stat3 activation in human keratinocytes and fibroblasts through reactive oxygen species and DNA damage

(2010) Toshinori Bito et al.   EXPERIMENTAL DERMATOLOGY

The flavonoids apigenin and luteolin suppress ultraviolet A-induced matrix metalloproteinase-1 expression via MAPKs and AP-1-dependent signaling in HaCaT cells

(2010) Yong Pil Hwang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The Flavonoid Luteolin Increases the Resistance of Normal, but Not Malignant Keratinocytes, Against UVB-Induced Apoptosis

(2010) Lien Verschooten et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism?

(2010) Stéphane Mouret et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Oral Feeding of Pomegranate Fruit Extract Inhibits Early Biomarkers of UVB Radiation-induced Carcinogenesis in SKH-1 Hairless Mouse Epidermis

(2010) Farrukh Afaq et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms

(2009) Joi A. Nichols et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-κB pathway in human epidermoid carcinoma A431 cells

(2009) Preeti Roy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interaction of Tea Catechin (—)-Epigallocatechin Gallate with Lipid Bilayers

(2009) Yen Sun et al.   BIOPHYSICAL JOURNAL

Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase

(2009) Jung Yeon Kwon et al.   CARCINOGENESIS

Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin

(2009) Farrukh Afaq et al.   EXPERIMENTAL DERMATOLOGY

Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin

(2009) Melissa M. Camouse et al.   EXPERIMENTAL DERMATOLOGY

Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture

(2009) Anika E. Wagner et al.   EXPERIMENTAL DERMATOLOGY

In vitro and in vivo anti-photoaging effects of an isoflavone extract from soybean cake

(2009) Tsu-Man Chiu et al.   JOURNAL OF ETHNOPHARMACOLOGY

A review of human carcinogens—Part D: radiation

(2009) Fatiha El Ghissassi et al.   LANCET ONCOLOGY

Influence of cytosine methylation on ultraviolet-induced cyclobutane pyrimidine dimer formation in genomic DNA

(2009) Patrick J. Rochette et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Protective Effects of Standardized Pomegranate (Punica granatumL.) Polyphenolic Extract in Ultraviolet-Irradiated Human Skin Fibroblasts

(2008) Lisbeth A. Pacheco-Palencia et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of UVB-Induced Skin Tumor Development by Drinking Green Tea Polyphenols Is Mediated Through DNA Repair and Subsequent Inhibition of Inflammation

(2008) Syed M. Meeran et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes

(2008) Jack Zhang et al.   MOLECULAR CARCINOGENESIS

Silymarin, a Flavonoid from Milk Thistle (Silybum marianum L.), Inhibits UV-induced Oxidative Stress Through Targeting Infiltrating CD11b+Cells in Mouse Skin

(2008) Santosh K. Katiyar et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Green Tea Phenol Extracts Reduce UVB-induced DNA Damage in Human Cells via Interleukin-12

(2008) Agatha Schwarz et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY