Article
Ophthalmology
Gareth Lingham, David A. Mackey, Kun Zhu, Robyn M. Lucas, Lucinda J. Black, Wendy H. Oddy, Patrick Holt, John P. Walsh, Paul G. Sanfilippo, Wendy Chan She Ping-Delfos, Seyhan Yazar
Summary: The study found that myopia in young adulthood was closely related to lower 25(OH)D concentrations at age 20, as well as low vitamin D levels at ages 17 and 20. There was no significant association between myopia and 25(OH)D concentrations at younger ages. Individuals with myopia at age 20 showed a declining trajectory of 25(OH)D concentrations compared to non-myopic peers, with greater differences in trajectory among non-Caucasians.
ACTA OPHTHALMOLOGICA
(2021)
Article
Ophthalmology
Xiangui He, Padmaja Sankaridurg, Jingjing Wang, Jun Chen, Thomas Naduvilath, Mingguang He, Zhuoting Zhu, Wayne Li, Ian G. Morgan, Shuyu Xiong, Jianfeng Zhu, Haidong Zou, Kathryn A. Rose, Bo Zhang, Rebecca Weng, Serge Resnikoff, Xun Xu
Summary: The study aimed to evaluate the efficacy of time spent outdoors per school day on myopia onset and shift. The results showed that increasing outdoor time reduced the risk of myopia, especially in nonmyopic children. The protective effect was related to the duration of exposure and light intensity.
Article
Public, Environmental & Occupational Health
Dariusch Philipp, Mandy Vogel, Manuela Brandt, Franziska G. Rauscher, Andreas Hiemisch, Siegfried Wahl, Wieland Kiess, Tanja Poulain
Summary: This study examined environmental and social risk factors for myopia in children and adolescents in Germany. The findings showed that less frequent outdoor activity and longer near work sessions were significantly associated with myopia. Additionally, children with a lower socioeconomic status were more likely to engage in longer periods of outdoor and near work activities.
Review
Biochemistry & Molecular Biology
Hei-Nga Chan, Xiu-Juan Zhang, Xiang-Tian Ling, Christine Huyen-Trang Bui, Yu-Meng Wang, Patrick Ip, Wai-Kit Chu, Li-Jia Chen, Clement C. Tham, Jason C. Yam, Chi-Pui Pang
Summary: This paper provides a systematic review of recent findings on the association between vitamin D and different ocular diseases, including myopia, age-related macular degeneration (AMD), glaucoma, diabetic retinopathy (DR), dry eye syndrome (DES), thyroid eye disease (TED), uveitis, retinoblastoma (RB), cataract, and others. Evidence suggests a relationship between vitamin D deficiency and myopia, AMD, DR, and DES, but limited evidence is available for the association with other ocular diseases such as glaucoma, TED, and RB.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Clinical Neurology
Prince Sebastian, Nicolas Cherbuin, Lisa F. Barcellos, Shelly Roalstad, Charles Casper, Janace Hart, Gregory S. Aaen, Lauren Krupp, Leslie Benson, Mark Gorman, Meghan Candee, Tanuja Chitnis, Manu Goyal, Benjamin Greenberg, Soe Mar, Moses Rodriguez, Jennifer Rubin, Teri Schreiner, Amy Waldman, Bianca Weinstock-Guttman, Jennifer Graves, Emmanuelle Waubant, Robyn Lucas
Summary: This study aims to determine the effects of sun exposure and ultraviolet radiation (UVR) exposure on the risk of pediatric-onset multiple sclerosis (MS). The results showed that spending more time outdoors during summer and higher summer ambient UVR dose were associated with a reduced risk of developing MS in children.
Article
Public, Environmental & Occupational Health
Jingjing Wang, Padmaja Sankaridurg, Thomas Naduvilath, Wayne Li, Ian G. Morgan, Kathryn A. Rose, Rebecca Weng, Xun Xu, Xiangui He
Summary: This study investigates the relationship between outdoor time and academic performance among school-aged children. It found that outdoor time and sleep duration were non-linearly associated with academic performance, suggesting that promoting outdoor time may not have a negative impact on academic performance.
Review
Medicine, General & Internal
Myriam Abboud, Fatme Al Anouti, Dimitrios Papandreou, Rana Rizk, Nadine Mahboub, Suzan Haidar
Summary: Multiple studies have investigated the relationship between vitamin D status and blood pressure in children and adolescents, with varying results that mainly point towards a lack of association. Prospective cohort studies showed no significant association, and flaws were identified in the majority of non-prospective cohort studies.
SYSTEMATIC REVIEWS
(2021)
Article
Environmental Sciences
Bin Wang, Heng Wan, Jing Cheng, Yingchao Chen, Yuying Wang, Yi Chen, Chi Chen, Wen Zhang, Fangzhen Xia, Ningjian Wang, Li Wang, Yingli Lu
Summary: Higher blood lead levels were associated with increased urinary albumin excretion in diabetic patients with vitamin D deficiency. However, this association was attenuated or non-significant in patients with sufficient vitamin D levels. The combination of high blood lead and low vitamin D levels corresponded to significantly higher urinary albumin-to-creatinine ratio. It was also found that the impact of blood lead levels on urinary albumin excretion was more pronounced in patients with reduced estimated glomerular filtration rate in the group with vitamin D deficiency.
ENVIRONMENTAL POLLUTION
(2021)
Article
Multidisciplinary Sciences
Gareth Lingham, Seyhan Yazar, Robyn M. Lucas, Elizabeth Milne, Alex W. Hewitt, Christopher J. Hammond, Stuart MacGregor, Kathryn A. Rose, Fred K. Chen, Mingguang He, Jeremy A. Guggenheim, Michael W. Clarke, Seang-Mei Saw, Cathy Williams, Minas T. Coroneo, Leon Straker, David A. Mackey
Summary: The study found that spending more time outdoors during childhood can reduce the risk of myopia in young adulthood, and outdoor activities in later adolescence and young adulthood are also associated with a decreased risk of late-onset myopia. Engaging in outdoor activities during both childhood and adolescence is linked to a lower incidence of myopia in young adulthood.
SCIENTIFIC REPORTS
(2021)
Review
Food Science & Technology
Chao Lu, Weihua Zhou, Xinjue He, Xinxin Zhou, Chaohui Yu
Summary: The study found that patients with celiac disease have lower Vitamin D levels compared to controls, which improve after treatment, but there is no difference in Vitamin D Receptor genotypes between the two groups.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Review
Nutrition & Dietetics
Rakesh Balachandar, Raghu Pullakhandam, Bharati Kulkarni, Harshpal Singh Sachdev
Summary: This study found that cholecalciferol was more effective than ergocalciferol in improving vitamin D status and regulating PTH levels, regardless of participant demographics, dosage, and vehicle of supplementation.
Review
Nutrition & Dietetics
Zuqun Wang, Rui Ding, Juan Wang
Summary: The association between vitamin D status and autism spectrum disorder (ASD) has been well-investigated, with lower vitamin D levels being associated with higher risk of ASD. Moreover, decreased early-life vitamin D concentration in children with ASD and higher likelihood of developing ASD in children with reduced maternal or neonatal vitamin D were observed in prospective studies. This highlights the importance of detecting and intervening in vitamin D deficiency in ASD patients, pregnant, and lactating women for clinical and public health significance.
Review
Nutrition & Dietetics
Karen Christina Walker, Fanney Thorsteinsdottir, Henrik Thybo Christesen, Vibeke Elisabeth Hjortdal, Berit Lilienthal Heitmann, Ina Olmer Specht, Mina Nicole Handel
Summary: This study found no significant association between vitamin D supplementation or vitamin D status during pregnancy and congenital anomalies (CAs) in the offspring. However, the interpretation of the results should be cautious due to the limitations of the current studies.
Article
Medicine, General & Internal
Fan Gao, Peng Li, Ya-Qian Liu, Yan Chen
Summary: The study found a high detection rate of serum 25(OH)D deficiency in myopic children and a close relationship between serum 25(OH)D concentration and myopia severity. Serum 25(OH)D deficiency may be associated with an increased prevalence of developing moderate to high myopia.
Article
Biochemistry & Molecular Biology
Thomas Mueller, Lutz Lohse, Andreas Blodau, Katja Frommholz
Summary: The study investigated the impact of 25-hydroxy-vitamin D plasma concentrations on blood parameters, indicating that changes in blood parameters were affected by the variation in plasma levels of this form of vitamin D. Additionally, the elevation of vitamin D plasma levels was found to provide enhanced preconditions for better tissue oxygenation on a cellular level.
Review
Ophthalmology
Zhujun Fu, Hao Hong, Zhicai Su, Bin Lou, Chen-Wei Pan, Hu Liu
BRITISH JOURNAL OF OPHTHALMOLOGY
(2020)
Article
Ophthalmology
Chen-Wei Pan, Bing Shi, Hua Zhong, Jun Li, Qin Chen
OPHTHALMIC EPIDEMIOLOGY
(2020)
Article
Geriatrics & Gerontology
Jing-Hong Liu, Qing-Hua Ma, Hong-Peng Sun, Yong Xu, Chen-Wei Pan
Summary: Poor sleep quality is associated with increased odds of falls among older adults, and depressive symptoms partially mediate this association.
AGING & MENTAL HEALTH
(2021)
Article
Geriatrics & Gerontology
Jing-Hong Liu, You-Jie Zhang, Qing-Hua Ma, Hong-Peng Sun, Yong Xu, Chen-Wei Pan
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2020)
Article
Multidisciplinary Sciences
Ye Zhuang, Qing-Hua Ma, Chen-Wei Pan, Jun Lu
Article
Endocrinology & Metabolism
Jing-Hong Liu, Yu-Xi Qian, Qing-Hua Ma, Hong-Peng Sun, Yong Xu, Chen-Wei Pan
DIABETOLOGY & METABOLIC SYNDROME
(2020)
Article
Ophthalmology
Chaofu Ke, Hua Xu, Qin Chen, Hua Zhong, Chen-Wei Pan
Summary: This study identified 20 metabolic biomarkers as potential serum biomarkers for high myopia, and found metabolic pathways related to high myopia, such as increased energy metabolism and increased oxidative stress. These findings could provide valuable insights for improving the understanding of disease pathogenesis and developing new therapeutic measures.
Article
Health Care Sciences & Services
Ruxu You, Jinyu Liu, Zhihao Yang, Chenwei Pan, Qinghua Ma, Nan Luo
HEALTH AND QUALITY OF LIFE OUTCOMES
(2020)
Article
Ophthalmology
Chen-Wei Pan, Chaofu Ke, Qin Chen, Yi-Jin Tao, Xu Zha, Yuan-Ping Zhang, Hua Zhong
Article
Public, Environmental & Occupational Health
Chen-Wei Pan, Hua Zhong, Jun Li, Chen Suo, Pei Wang
Article
Public, Environmental & Occupational Health
Wei Shen, Qing Cun, Hua Zhong, Chen-Wei Pan, Jun Li, Qin Chen
Article
Health Care Sciences & Services
Chen-Wei Pan, Ruo-Yu Zhang, Nan Luo, Jun-Yi He, Rui-Jie Liu, Xiao-Hua Ying, Pei Wang
QUALITY OF LIFE RESEARCH
(2020)
Article
Environmental Sciences
Chenwei Pan, Huijuan Zhao, Qiaoling Du, Yong Xu, Dajun Tian, Shuo Xiao, Haiyin Wang, Xiao Wei, Chunfeng Wu, Yuanyuan Ruan, Chunhua Zhao, Gonghua Tao, Weiwei Zheng
Summary: Exposure to PCB28 can directly increase the risk of cognitive impairment in older Chinese females, according to the results of the Weitang Geriatric Diseases study. This finding is important for understanding the impact of PCBs on human cognition.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Biochemistry & Molecular Biology
Xiao-Wen Hou, Ying Wang, Chao-Fu Ke, Mei-Yan Li, Chen-Wei Pan
Summary: This study discusses the metabolic changes in neovascular diseases involving the retina and provides insights into the progress of the study from the perspective of metabolomics design and analysis. The study suggests a comparative strategy based on existing research, which aims to optimize the performance of newly identified biomarkers and provide additional reference for new biomarker discovery. Additionally, the study describes the metabolic mechanisms of retinal and choroidal neovascularization, offering potential opportunities for new therapeutic approaches.
Article
Endocrinology & Metabolism
Xue-Jiao Yang, Shun Tian, Qing-Hua Ma, Hong-Peng Sun, Yong Xu, Chen-Wei Pan