Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology

Nuclear membrane R-type calcium channels mediate cytosolic ET-1-induced increase of nuclear calcium in human vascular smooth muscle cells

(2015) Ghassan Bkaily et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

An Adaptive Association Test for Multiple Phenotypes with GWAS Summary Statistics

(2015) Junghi Kim et al.   GENETIC EPIDEMIOLOGY

Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval

(2015) Claudia Tamar Silva et al.   HUMAN GENETICS

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

(2015)   NATURE NEUROSCIENCE

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics

(2015) Sung Jin Park et al.   Scientific Reports

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Clinical pharmacogenetics implementation: Approaches, successes, and challenges

(2014) Kristin W. Weitzel et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Trafficking mechanisms and regulation of TRPC channels

(2014) Lorena Brito de Souza et al.   CELL CALCIUM

Pitx2, an Atrial Fibrillation Predisposition Gene, Directly Regulates Ion Transport and Intercalated Disc Genes

(2014) Y. Tao et al.   Circulation-Cardiovascular Genetics

Using pharmacogenetics in real time to guide therapy: the warfarin example

(2014) F. Aminkeng   CLINICAL GENETICS

The emerging era of pharmacogenomics: current successes, future potential, and challenges

(2014) J.W. Lee et al.   CLINICAL GENETICS

Diuretics in the treatment of hypertension. Part 1: thiazide and thiazide-like diuretics

(2014) Juan Tamargo et al.   EXPERT OPINION ON PHARMACOTHERAPY

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

(2014) Dan E Arking et al.   NATURE GENETICS

Selection bias in rheumatic disease research

(2014) Hyon K. Choi et al.   Nature Reviews Rheumatology

Generalized estimating equations for genome-wide association studies using longitudinal phenotype data

(2014) Colleen M. Sitlani et al.   STATISTICS IN MEDICINE

GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation

(2014) Dongjun Chung et al.   PLoS Genetics

A Multi-Trait, Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature, Fatness and Reproduction in Beef Cattle

(2014) Sunduimijid Bolormaa et al.   PLoS Genetics

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Missense Mutations in Plakophilin-2 Cause Sodium Current Deficit and Associate With a Brugada Syndrome Phenotype

(2013) Marina Cerrone et al.   CIRCULATION

QT interval prolongation and the risk of torsades de pointes: essentials for clinicians

(2013) Katy E. Trinkley et al.   CURRENT MEDICAL RESEARCH AND OPINION

Gene-Environment and Gene-Treatment Interactions in Type 2 Diabetes: Progress, pitfalls, and prospects

(2013) P. W. Franks et al.   DIABETES CARE

Genomic Association Analysis of Common Variants Influencing Antihypertensive Response to Hydrochlorothiazide

(2013) Stephen T. Turner et al.   HYPERTENSION

Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics

(2013) Caitrin W. McDonough et al.   JOURNAL OF HYPERTENSION

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

(2013) Minoli A Perera et al.   LANCET

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

Validation of a population-based method to assess drug-induced alterations in the QT interval: a self-controlled crossover study

(2013) Carlos Iribarren et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Drug–gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

(2013) C L Avery et al.   PHARMACOGENOMICS JOURNAL

Pharmacogenomics, ancestry and clinical decision making for global populations

(2013) E Ramos et al.   PHARMACOGENOMICS JOURNAL

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

(2013) J L Del-Aguila et al.   PHARMACOGENOMICS JOURNAL

Functional characterization of 32 CYP2C9 allelic variants

(2013) Y Niinuma et al.   PHARMACOGENOMICS JOURNAL

Gene–environment interactions in common mental disorders: an update and strategy for a genome-wide search

(2013) Rudolf Uher   SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY

Trends in Antihypertensive Medication Use and Blood Pressure Control Among United States Adults With Hypertension

(2012) Qiuping Gu et al.   CIRCULATION

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression

(2012) J D Duarte et al.   PHARMACOGENOMICS JOURNAL

QT-Interval Duration and Mortality Rate

(2011) Yiyi Zhang   ARCHIVES OF INTERNAL MEDICINE

Interaction of ACE and CYP11B2 Genes on Blood Pressure Response to Hydrochlorothiazide in Han Chinese Hypertensive Patients

(2011) Yun Li et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Genetic epidemiology with a Capital E, ten years after

(2011) Muin J. Khoury et al.   GENETIC EPIDEMIOLOGY

Transethnic meta-analysis of genomewide association studies

(2011) Andrew P. Morris   GENETIC EPIDEMIOLOGY

Genetics and Variable Drug Response

(2011) Russell A. Wilke et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Stanniocalcin 2 Is a Negative Modulator of Store-Operated Calcium Entry

(2011) W. Zeiger et al.   MOLECULAR AND CELLULAR BIOLOGY

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients

(2011) Kelly A. Birdwell et al.   Pharmacogenetics and Genomics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Modulators of normal electrocardiographic intervals identified in a large electronic medical record

(2010) Andrea H. Ramirez et al.   HEART RHYTHM

ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C

(2010) Jacques Fellay et al.   NATURE

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Gene–environment-wide association studies: emerging approaches

(2010) Duncan Thomas   NATURE REVIEWS GENETICS

ConsensusPathDB: toward a more complete picture of cell biology

(2010) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

Clinical Correlates and Heritability of QT Interval Duration in Blacks

(2009) Ermeg L. Akylbekova et al.   Circulation-Arrhythmia and Electrophysiology

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

Association of NOS1AP Genetic Variants With QT Interval Duration in Families From the Diabetes Heart Study

(2008) A. B. Lehtinen et al.   DIABETES

Genomic Association Analysis Suggests Chromosome 12 Locus Influencing Antihypertensive Response to Thiazide Diuretic

(2008) Stephen T. Turner et al.   HYPERTENSION

ConsensusPathDB—a database for integrating human functional interaction networks

(2008) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH