The role of macrophages in hypertension and its complications

Fate Mapping and Quantitation of Hematopoiesis In Vivo

(2016) Thomas Höfer et al.   Annual Review of Immunology

Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron

(2016) Jiandong Zhang et al.   Cell Metabolism

Global Disparities of Hypertension Prevalence and ControlClinical Perspective

(2016) Katherine T. Mills et al.   CIRCULATION

Interactions Between the Immune and the Renin–Angiotensin Systems in Hypertension

(2016) Nathan P. Rudemiller et al.   HYPERTENSION

Angiotensin II Regulation of Proliferation, Differentiation, and Engraftment of Hematopoietic Stem Cells

(2016) Seungbum Kim et al.   HYPERTENSION

Macrophages come to mind as keys to cognitive decline

(2016) D.G. Harrison et al.   JOURNAL OF CLINICAL INVESTIGATION

Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension

(2016) Giuseppe Faraco et al.   JOURNAL OF CLINICAL INVESTIGATION

Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI

(2016) J. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

(2015) S M Krishnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

(2015) Jonathan Jantsch et al.   Cell Metabolism

High salt primes a specific activation state of macrophages, M(Na)

(2015) Wu-Chang Zhang et al.   CELL RESEARCH

The Good and the Bad

(2015) Meredith Hay   CIRCULATION RESEARCH

Inflammation, Immunity, and Hypertensive End-Organ Damage

(2015) W. G. McMaster et al.   CIRCULATION RESEARCH

Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in HypertensionNovelty and Significance

(2015) Kandarp H. Shah et al.   CIRCULATION RESEARCH

NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy

(2015) Koumei Shirasuna et al.   ENDOCRINOLOGY

Microglia Participate in Neurogenic Regulation of HypertensionNovelty and Significance

(2015) Xiao Z. Shen et al.   HYPERTENSION

Inhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertension

(2015) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

High salt reduces the activation of IL-4– and IL-13–stimulated macrophages

(2015) Katrina J. Binger et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune Mechanisms in Arterial Hypertension

(2015) U. Wenzel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Magnetic resonance–determined sodium removal from tissue stores in hemodialysis patients

(2015) Anke Dahlmann et al.   KIDNEY INTERNATIONAL

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Mohammad H Forouzanfar et al.   LANCET

Tumor Necrosis Factor - Alpha Is Essential for Angiotensin II-Induced Ventricular Remodeling: Role for Oxidative Stress

(2015) Srinivas Sriramula et al.   PLoS One

Sodium balance is not just a renal affair

(2014) Jens Titze   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

5TNF-α and IL-1β Neutralization Ameliorates Angiotensin II-Induced Cardiac Damage in Male Mice

(2014) Yueli Wang et al.   ENDOCRINOLOGY

Tumor Necrosis Factor-α Produced in the Kidney Contributes to Angiotensin II–dependent Hypertension

(2014) Jiandong Zhang et al.   HYPERTENSION

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Inflammatory Monocytes Determine Endothelial Nitric-oxide Synthase Uncoupling and Nitro-oxidative Stress Induced by Angiotensin II

(2014) Sabine Kossmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor–mediated kidney fibrosis

(2014) Jian-dong Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

23 Na Magnetic Resonance Imaging-Determined Tissue Sodium in Healthy Subjects and Hypertensive Patients

(2013) Christoph Kopp et al.   HYPERTENSION

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

(2013) Helge Wiig et al.   JOURNAL OF CLINICAL INVESTIGATION

Infliximab, a TNF-α inhibitor, reduces 24-h ambulatory blood pressure in rheumatoid arthritis patients

(2013) S Yoshida et al.   JOURNAL OF HUMAN HYPERTENSION

Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania

(2013) Djalma S Lima-Junior et al.   NATURE MEDICINE

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

(2012) Paul M Ridker et al.   CIRCULATION

A Novel Role for Type 1 Angiotensin Receptors on T Lymphocytes to Limit Target Organ Damage in Hypertension

(2012) Jian-dong Zhang et al.   CIRCULATION RESEARCH

Essential Role of MicroRNA-155 in Regulating Endothelium-Dependent Vasorelaxation by Targeting Endothelial Nitric Oxide Synthase

(2012) Hai-Xiang Sun et al.   HYPERTENSION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

(2011) Paul M Ridker et al.   AMERICAN HEART JOURNAL

Lysozyme M–Positive Monocytes Mediate Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2011) Philip Wenzel et al.   CIRCULATION

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α

(2011) Leslie A Bruggeman et al.   LABORATORY INVESTIGATION

Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

(2010) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Brain Microglial Cytokines in Neurogenic Hypertension

(2010) Peng Shi et al.   HYPERTENSION

Mononuclear Phagocyte System Depletion Blocks Interstitial Tonicity-Responsive Enhancer Binding Protein/Vascular Endothelial Growth Factor C Expression and Induces Salt-Sensitive Hypertension in Rats

(2010) Agnes Machnik et al.   HYPERTENSION

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure

(2010) Petra Kleinbongard et al.   PHARMACOLOGY & THERAPEUTICS

Tumor Necrosis Factor-α Antagonists Improve Aortic Stiffness in Patients With Inflammatory Arthropathies

(2009) Kristin Angel et al.   HYPERTENSION

A Role for Angiotensin II Type 1 Receptors on Bone Marrow-Derived Cells in the Pathogenesis of Angiotensin II–Dependent Hypertension

(2009) Steven D. Crowley et al.   HYPERTENSION

TNF-α drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice

(2009) Peter Baluk et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

(2009) Agnes Machnik et al.   NATURE MEDICINE

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system

(2009) J. Stegbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Involvement of Tumor Necrosis Factor-α in Angiotensin II–Mediated Effects on Salt Appetite, Hypertension, and Cardiac Hypertrophy

(2008) Srinivas Sriramula et al.   HYPERTENSION

Role of Inflammation in the Development of Renal Damage and Dysfunction in Angiotensin II–Induced Hypertension

(2008) Tang-Dong Liao et al.   HYPERTENSION

Macrophage diversity in renal injury and repair

(2008) Sharon D. Ricardo et al.   JOURNAL OF CLINICAL INVESTIGATION

Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells

(2008) Hideki Kato et al.   LABORATORY INVESTIGATION