Essential role for EGFR tyrosine kinase and ER stress in myocardial infarction in type 2 diabetes

EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice

(2016) Weixin Li et al.   Scientific Reports

Crosstalk Between MAPK/ERK and PI3K/AKT Signal Pathways During Brain Ischemia/Reperfusion

(2015) Jing Zhou et al.   ASN Neuro

EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse model

(2015) Dandan Liang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Inhibition of Src Kinase Blocks High Glucose-Induced EGFR Transactivation and Collagen Synthesis in Mesangial Cells and Prevents Diabetic Nephropathy in Mice

(2013) K. Taniguchi et al.   DIABETES

Enhanced NF- B Activity Impairs Vascular Function Through PARP-1-, SP-1-, and COX-2-Dependent Mechanisms in Type 2 Diabetes

(2013) M. Kassan et al.   DIABETES

A Novel Role for Epidermal Growth Factor Receptor Tyrosine Kinase and Its Downstream Endoplasmic Reticulum Stress in Cardiac Damage and Microvascular Dysfunction in Type 1 Diabetes Mellitus

(2012) Maria Galán et al.   HYPERTENSION

Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury

(2012) Saghir Akhtar et al.   PLoS One

Chronic Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase and Extracellular Signal-Regulated Kinases 1 and 2 (ERK1/2) Augments Vascular Response to Limb Ischemia in Type 2 Diabetic Mice

(2011) Soo-Kyoung Choi et al.   AMERICAN JOURNAL OF PATHOLOGY

Deficiency in TIMP-3 increases cardiac rupture and mortality post-myocardial infarction via EGFR signaling: beneficial effects of cetuximab

(2011) Lamis Hammoud et al.   BASIC RESEARCH IN CARDIOLOGY

Activation of epidermal growth factor receptor mediates reperfusion arrhythmias in anaesthetized rats

(2011) Mei Feng et al.   CARDIOVASCULAR RESEARCH

Differences in myocardial PTEN expression and Akt signalling in type 2 diabetic and nondiabetic patients undergoing coronary bypass surgery

(2011) Baohua Wang et al.   CLINICAL ENDOCRINOLOGY

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice

(2011) Ali Amin et al.   JOURNAL OF PATHOLOGY

Endoplasmic Reticulum Stress in Diabetic Hearts Abolishes Erythropoietin-Induced Myocardial Protection by Impairment of Phospho–Glycogen Synthase Kinase-3β–Mediated Suppression of Mitochondrial Permeability Transition

(2009) Takayuki Miki et al.   DIABETES

Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase

(2009) Khalid Matrougui   DIABETES-METABOLISM RESEARCH AND REVIEWS

Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: Role in leptin-induced hypertension

(2008) Anna Jamroz-Wiśniewska et al.   BIOCHEMICAL PHARMACOLOGY

Elevated Epidermal Growth Factor Receptor Phosphorylation Induces Resistance Artery Dysfunction in Diabetic db/db Mice

(2008) S. Belmadani et al.   DIABETES