Does agricultural use of azole fungicides contribute to resistance in the human pathogen Aspergillus fumigatus ?

Fungicides induced triazole-resistance in Aspergillus fumigatus associated with mutations of TR46/Y121F/T289A and its appearance in agricultural fields

(2017) Jingbei Ren et al.   JOURNAL OF HAZARDOUS MATERIALS

Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? A mini review

(2016) Aícha Daniela Ribas e Ribas et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Demethylase Inhibitor Fungicide Resistance in Pyrenophora teres f. sp. teres Associated with Target Site Modification and Inducible Overexpression of Cyp51

(2016) Wesley J. Mair et al.   Frontiers in Microbiology

Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

(2016) Joel D. A. Tyndall et al.   PLoS One

Azole Resistance inAspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

(2015) Paul E. Verweij et al.   CLINICAL INFECTIOUS DISEASES

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) fromAspergillus fumigatusand Molecular Basis for the Development of Antifungal Drugs

(2015) Tatiana Y. Hargrove et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First Detection of TR46/Y121F/T289A and TR34/L98H Alterations in Aspergillus fumigatus Isolates from Azole-Naive Patients in Denmark despite Negative Findings in the Environment

(2014) K. M. T. Astvad et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Development of cross-resistance by Aspergillus fumigatus to clinical azoles following exposure to prochloraz, an agricultural azole

(2014) Isabel Faria-Ramos et al.   BMC MICROBIOLOGY

Paralog Re-Emergence: A Novel, Historically Contingent Mechanism in the Evolution of Antimicrobial Resistance

(2014) Nichola J. Hawkins et al.   MOLECULAR BIOLOGY AND EVOLUTION

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus 

(2013) Marcin G. Fraczek et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Characterization of the sterol 14α-demethylases ofFusarium graminearumidentifies a novel genus-specific CYP51 function

(2013) Jieru Fan et al.   NEW PHYTOLOGIST

Environmental fungicides and triazole resistance inAspergillus

(2013) Paul Bowyer et al.   PEST MANAGEMENT SCIENCE

Assessment of selection and resistance risk for demethylation inhibitor fungicides inAspergillus fumigatusin agriculture and medicine: a critical review

(2013) Ulrich Gisi   PEST MANAGEMENT SCIENCE

Constraints on the evolution of azole resistance in plant pathogenic fungi

(2013) H. J. Cools et al.   PLANT PATHOLOGY

Correction: Emergence of Azole-Resistant Aspergillus fumigatus Strains due to Agricultural Azole Use Creates an Increasing Threat to Human Health

(2013) Anuradha Chowdhary et al.   PLoS Pathogens

High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates

(2012) A. Buied et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Triazole fungicides and the selection of resistance to medical triazoles in the opportunistic mouldAspergillus fumigatus

(2012) Paul E Verweij et al.   PEST MANAGEMENT SCIENCE

Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus

(2012) Eveline Snelders et al.   PLoS One

Azole Resistance in Aspergillus fumigatus Isolates from the ARTEMIS Global Surveillance Study Is Primarily Due to the TR/L98H Mutation in thecyp51AGene

(2011) Shawn R. Lockhart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evidence for genetic differentiation and variable recombination rates among Dutch populations of the opportunistic human pathogenAspergillus fumigatus

(2011) CORNÉ H. W. KLAASSEN et al.   MOLECULAR ECOLOGY

Molecular Modelling of the Emergence of Azole Resistance in Mycosphaerella graminicola

(2011) Jonathan G. L. Mullins et al.   PLoS One

Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-  Demethylase (CYP51) Isoenzymes A and B

(2010) A. G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14 -Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B

(2010) C. M. Martel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Possible Environmental Origin of Resistance of Aspergillus fumigatus to Medical Triazoles

(2009) E. Snelders et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus

(2008) Céline M. O’Gorman et al.   NATURE

Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism

(2008) Eveline Snelders et al.   PLOS MEDICINE