Impaired lysosomal activity mediated autophagic flux disruption by graphite carbon nanofibers induce apoptosis in human lung epithelial cells through oxidative stress and energetic impairment
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Title
Impaired lysosomal activity mediated autophagic flux disruption by graphite carbon nanofibers induce apoptosis in human lung epithelial cells through oxidative stress and energetic impairment
Authors
Keywords
Graphite carbon nanofibers (GCNF), Autophagy, Apoptosis, Mitochondrial damage, Destabilization of lysosomes, ATP loss, Reactive oxygen species (ROS), Genotoxicity
Journal
Particle and Fibre Toxicology
Volume 14, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-04-28
DOI
10.1186/s12989-017-0194-4
References
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Related references
Note: Only part of the references are listed.- mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
- (2016) Claudia Manzoni et al. Scientific Reports
- Broad Family of Carbon Nanoallotropes: Classification, Chemistry, and Applications of Fullerenes, Carbon Dots, Nanotubes, Graphene, Nanodiamonds, and Combined Superstructures
- (2015) Vasilios Georgakilas et al. CHEMICAL REVIEWS
- Electrospun Carbon Nanofibers Decorated with Ag–Pt Bimetallic Nanoparticles for Selective Detection of Dopamine
- (2014) Yunpeng Huang et al. ACS Applied Materials & Interfaces
- Toxicity of carboxylated carbon nanotubes in endothelial cells is attenuated by stimulation of the autophagic flux with the release of nanomaterial in autophagic vesicles
- (2014) Martina Orecna et al. Nanomedicine-Nanotechnology Biology and Medicine
- Autophagy Controls the Kinetics and Extent of Mitochondrial Apoptosis by Regulating PUMA Levels
- (2014) Jacqueline Thorburn et al. Cell Reports
- Pulmonary toxicity of carbon nanotubes and asbestos — Similarities and differences
- (2013) Ken Donaldson et al. ADVANCED DRUG DELIVERY REVIEWS
- Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons
- (2013) Anna A. Shvedova et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Intracellular reactive oxidative stress, cell proliferation and apoptosis of Schwann cells on carbon nanofibrous substrates
- (2013) Shilpee Jain et al. BIOMATERIALS
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells
- (2013) Andrew M. Hau et al. PLoS One
- Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages
- (2013) Bin Wan et al. TOXICOLOGY LETTERS
- Occupational Nanosafety Considerations for Carbon Nanotubes and Carbon Nanofibers
- (2012) Vincent Castranova et al. ACCOUNTS OF CHEMICAL RESEARCH
- Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials
- (2012) Fernando Torres Andón et al. ACCOUNTS OF CHEMICAL RESEARCH
- Cerium Dioxide Nanoparticles Induce Apoptosis and Autophagy in Human Peripheral Blood Monocytes
- (2012) Salik Hussain et al. ACS Nano
- The end of autophagic cell death?
- (2012) Shensi Shen et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Uptake of fluorescent nano beads into BY2-cells involves clathrin-dependent and clathrin-independent endocytosis
- (2012) Vera Bandmann et al. FEBS LETTERS
- Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos
- (2012) Ashley R Murray et al. Particle and Fibre Toxicology
- Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
- (2012) Stephan T Stern et al. Particle and Fibre Toxicology
- Ninety-Day Inhalation Toxicity Study With A Vapor Grown Carbon Nanofiber in Rats
- (2012) Michael P. DeLorme et al. TOXICOLOGICAL SCIENCES
- Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress
- (2012) Anna A. Shvedova et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Toxicity Evaluation of Carbon Nanotubes in Normal Human Bronchial Epithelial Cells
- (2011) Sandeep Mittal et al. Journal of Biomedical Nanotechnology
- Force- and Ca2+-dependent internalization of integrins in cultured endothelial cells
- (2011) D. Kiyoshima et al. JOURNAL OF CELL SCIENCE
- Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1
- (2011) Tridib Bhowmick et al. JOURNAL OF CONTROLLED RELEASE
- Inhibition of MTOR Disrupts Autophagic Flux in Podocytes
- (2011) D. P. Cina et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The Role of Autophagy in Cancer: Therapeutic Implications
- (2011) Z. J. Yang et al. MOLECULAR CANCER THERAPEUTICS
- Alpha-alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response
- (2011) Haiyan Li et al. Nature Nanotechnology
- Nanoparticle exposure at nanotechnology workplaces: A review
- (2011) Thomas AJ Kuhlbusch et al. Particle and Fibre Toxicology
- Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos?
- (2011) E.R. Kisin et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling
- (2011) H-L Liu et al. Cell Death & Disease
- Toxicity assessment of nanomaterials: methods and challenges
- (2010) Alok Dhawan et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Pathophysiology of neuropathic lysosomal storage disorders
- (2010) Cinzia Maria Bellettato et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Rapid translocation of nanoparticles from the lung airspaces to the body
- (2010) Hak Soo Choi et al. NATURE BIOTECHNOLOGY
- Chemical modulators of autophagy as biological probes and potential therapeutics
- (2010) Angeleen Fleming et al. Nature Chemical Biology
- Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes
- (2010) Robert R Mercer et al. Particle and Fibre Toxicology
- Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction
- (2010) Denise N. Johnson-Lyles et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Carbon nanofibers and carbon nanotubes in regenerative medicine
- (2009) Phong A. Tran et al. ADVANCED DRUG DELIVERY REVIEWS
- Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystal
- (2009) Qiang Zhang et al. Autophagy
- Multiple roles of the cytoskeleton in autophagy
- (2009) Iryna Monastyrska et al. BIOLOGICAL REVIEWS
- Life and death partners: apoptosis, autophagy and the cross-talk between them
- (2009) A Eisenberg-Lerner et al. CELL DEATH AND DIFFERENTIATION
- Inhaled carbon nanotubes reach the subpleural tissue in mice
- (2009) Jessica P. Ryman-Rasmussen et al. Nature Nanotechnology
- Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
- (2008) S Sarkar et al. CELL DEATH AND DIFFERENTIATION
- Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies
- (2008) Jingkun Jiang et al. JOURNAL OF NANOPARTICLE RESEARCH
- In silico studies with human DNA topoisomerase-II alpha to unravel the mechanism of in vitro genotoxicity of benzene and its metabolites
- (2008) Alok Kumar Pandey et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
- (2008) Andrea Williams et al. Nature Chemical Biology
- Autophagic cell death: the story of a misnomer
- (2008) Guido Kroemer et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lysosomal membrane permeabilization in cell death
- (2008) P Boya et al. ONCOGENE
- Graphitic carbon nanofiber-poly(acrylate) polymer brushes as gas sensors
- (2008) Lang Li et al. SENSORS AND ACTUATORS B-CHEMICAL
- Induction of Autophagy in Porcine Kidney Cells by Quantum Dots: A Common Cellular Response to Nanomaterials?
- (2008) Stephan T. Stern et al. TOXICOLOGICAL SCIENCES
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