HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway
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Title
HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2017, Issue -, Pages 1-10
Publisher
Hindawi Limited
Online
2017-05-03
DOI
10.1155/2017/3160360
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- (2016) Yanlan Chen et al. Oxidative Medicine and Cellular Longevity
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- (2016) Himakarnika Alluri et al. PLoS One
- Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death
- (2015) Eran Schmukler et al. Oncotarget
- Ras inhibition enhances autophagy, which partially protects cells from death
- (2015) Eran Schmukler et al. Oncotarget
- HIV-1 Tat C phosphorylates VE-cadherin complex and increases human brain microvascular endothelial cell permeability
- (2014) Ritu Mishra et al. BMC NEUROSCIENCE
- HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-β/Smad signaling
- (2014) Ibolya E. András et al. EXPERIMENTAL CELL RESEARCH
- Differential Effects of Tat Proteins Derived from HIV-1 Subtypes B and Recombinant CRF02_AG on Human Brain Microvascular Endothelial Cells: Implications for Blood–Brain Barrier Dysfunction
- (2014) Shawna M Woollard et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- PPAR Agonist-Mediated Protection against HIV Tat-Induced Cerebrovascular Toxicity is Enhanced in MMP-9-Deficient Mice
- (2014) Wen Huang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders
- (2014) F. Niu et al. JOURNAL OF NEUROSCIENCE
- HIV-1/Cocaine Induced Oxidative Stress Disrupts Tight Junction Protein-1 in Human Pulmonary Microvascular Endothelial Cells: Role of Ras/ERK1/2 Pathway
- (2014) Pranjali Dalvi et al. PLoS One
- Therapeutic effect of farnesylthiosalicylic acid on adjuvant-induced arthritis through suppressed release of inflammatory cytokines
- (2013) E. Aizman et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Contributions of Degradation and Brain-to-blood Elimination Across the Blood—Brain Barrier to Cerebral Clearance of Human Amyloid-β Peptide(1-40) in Mouse Brain
- (2013) Shingo Ito et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Endolysosome involvement in HIV-1 transactivator protein-induced neuronal amyloid beta production
- (2013) Xuesong Chen et al. NEUROBIOLOGY OF AGING
- HIV-1 Tat Interacts with and Regulates the Localization and Processing of Amyloid Precursor Protein
- (2013) Jiyoung Kim et al. PLoS One
- Nf1 Loss and Ras Hyperactivation in Oligodendrocytes Induce NOS-Driven Defects in Myelin and Vasculature
- (2013) Debra A. Mayes et al. Cell Reports
- Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells
- (2012) Ibolya E. András et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Amyloid beta accumulation in HIV-1-infected brain: The role of the blood brain barrier
- (2012) Ibolya E. András et al. IUBMB LIFE
- Cell Surface Expression of the Major Amyloid-β Peptide (Aβ)-degrading Enzyme, Neprilysin, Depends on Phosphorylation by Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK) and Dephosphorylation by Protein Phosphatase 1a
- (2012) Naomasa Kakiya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Breaking down the barrier: The effects of HIV-1 on the blood–brain barrier
- (2011) Marianne Strazza et al. BRAIN RESEARCH
- HIV-1 gp120-Induced Axonal Injury Detected by Accumulation of β-Amyloid Precursor Protein in Adult Rat Corpus Callosum
- (2011) Jingdong Zhang et al. Journal of Neuroimmune Pharmacology
- HIV-1 Tat neurotoxicity: A model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes
- (2011) Lokesh Agrawal et al. NEUROBIOLOGY OF DISEASE
- Peripheral Delivery of a CNS Targeted, Metalo-Protease Reduces Aβ Toxicity in a Mouse Model of Alzheimer's Disease
- (2011) Brian Spencer et al. PLoS One
- HIV proteins (gp120 and Tat) and methamphetamine in oxidative stress-induced damage in the brain: Potential role of the thiol antioxidant N-acetylcysteine amide
- (2010) Atrayee Banerjee et al. FREE RADICAL BIOLOGY AND MEDICINE
- Salirasib in the treatment of pancreatic cancer
- (2010) Ernesto Bustinza-Linares et al. Future Oncology
- HIV-1 protein-mediated amyloidogenesis in rat hippocampal cell cultures
- (2010) M.Y. Aksenov et al. NEUROSCIENCE LETTERS
- PPARα and PPARγ attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities
- (2009) Wen Huang et al. FASEB JOURNAL
- Down-regulation of neprilysin (EC3.4.24.11) expression in vascular endothelial cells by laminar shear stress involves NADPH oxidase-dependent ROS production
- (2009) Paul A. Fitzpatrick et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Intact Lipid Rafts Regulate HIV-1 Tat Protein-Induced Activation of the Rho Signaling and Upregulation of P-Glycoprotein in Brain Endothelial Cells
- (2009) Yu Zhong et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients
- (2009) Cristian L. Achim et al. Journal of Neuroimmune Pharmacology
- HIV-1-induced amyloid beta accumulation in brain endothelial cells is attenuated by simvastatin
- (2009) Ibolya E. András et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Caveolin-1 Regulates Human Immunodeficiency Virus-1 Tat-Induced Alterations of Tight Junction Protein Expression via Modulation of the Ras Signaling
- (2008) Y. Zhong et al. JOURNAL OF NEUROSCIENCE
- Simvastatin Protects against Amyloid and HIV-1 Tat-Induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells
- (2008) I. E. Andras et al. MOLECULAR PHARMACOLOGY
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